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1983 1
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546 results

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Page 1
Oral famotidine versus placebo in non-hospitalised patients with COVID-19: a randomised, double-blind, data-intense, phase 2 clinical trial.
Brennan CM, Nadella S, Zhao X, Dima RJ, Jordan-Martin N, Demestichas BR, Kleeman SO, Ferrer M, von Gablenz EC, Mourikis N, Rubin ME, Adnani H, Lee H, Ha T, Prum S, Schleicher CB, Fox SS, Ryan MG, Pili C, Goldberg G, Crawford JM, Goodwin S, Zhang X, Preall JB, Costa ASH, Conigliaro J, Masci JR, Yang J, Tuveson DA, Tracey KJ, Janowitz T. Brennan CM, et al. Gut. 2022 May;71(5):879-888. doi: 10.1136/gutjnl-2022-326952. Epub 2022 Feb 10. Gut. 2022. PMID: 35144974 Free PMC article. Clinical Trial.
Differences were independent of patient sex, race or ethnicity. Five self-limiting adverse events occurred (famotidine, n=2 (40%); placebo, n=3 (60%)). On day 7, fewer patients on famotidine had detectable interferon alpha plasma levels (p=0.04). ...Famotidine
Differences were independent of patient sex, race or ethnicity. Five self-limiting adverse events occurred (famotidine, n=2 (40%); pl …
A randomized clinical trial comparing the efficacy of ranitidine and famotidine on intragastric acidity in critically ill pediatric patients.
Aanpreung P, Vanprapar N, Susiva C, Parkpreaw C, Boonyachart C. Aanpreung P, et al. J Med Assoc Thai. 1998 Mar;81(3):185-9. J Med Assoc Thai. 1998. PMID: 9623009 Clinical Trial.
Three cases in the famotidine group had successful prophylaxis with total time pH > or = 4 more than 80 per cent. Famotidine appeared to have a trend toward increasing intragastric pH in critically ill pediatric patients....
Three cases in the famotidine group had successful prophylaxis with total time pH > or = 4 more than 80 per cent. Famotidine
Effect of famotidine on cognitive and behavioral dysfunctions induced in post-COVID-19 infection: A randomized, double-blind, and placebo-controlled study.
Momtazmanesh S, Ansari S, Izadi Z, Shobeiri P, Vatankhah V, Seifi A, Ghiasvand F, Bahrami M, Salehi M, Noorbala AA, Akhondzadeh S. Momtazmanesh S, et al. J Psychosom Res. 2023 Sep;172:111389. doi: 10.1016/j.jpsychores.2023.111389. Epub 2023 May 31. J Psychosom Res. 2023. PMID: 37327698 Free PMC article. Clinical Trial.

Regarding the MoCA scale, the famotidine group had a significantly higher score at weeks 6 and 12 (p = 0.001, p < 0.001, respectively). ...CONCLUSION: Our study supports safety and efficacy of famotidine in treating cognitive impairment, depression and anxiety sy

Regarding the MoCA scale, the famotidine group had a significantly higher score at weeks 6 and 12 (p = 0.001, p < 0.001, respectiv

Pharmacokinetics and pharmacodynamics of famotidine and ranitidine in critically ill children.
Madani S, Kauffman R, Simpson P, Lehr VT, Lai ML, Sarniak A, Tolia V. Madani S, et al. J Clin Pharmacol. 2014 Feb;54(2):201-5. doi: 10.1002/jcph.219. Epub 2013 Nov 20. J Clin Pharmacol. 2014. PMID: 24258773 Free article. Clinical Trial.
Twenty-four children randomized to either famotidine (n = 12) or ranitidine (n = 12). Sixteen out of twenty-four completed both PK and PD study arms (7/12 famotidine; 4.7 3.4 years; 9/12 ranitidine; 6.6 4.7 years; p = 0.38). ...Ratio of AUC pH to AUC drug concentrat …
Twenty-four children randomized to either famotidine (n = 12) or ranitidine (n = 12). Sixteen out of twenty-four completed both PK an …
Pharmacokinetics and efficacy of intravenous famotidine in adult cattle.
Balcomb CC, Heller MC, Chigerwe M, Knych HK, Meyer AM. Balcomb CC, et al. J Vet Intern Med. 2018 May;32(3):1283-1289. doi: 10.1111/jvim.15080. Epub 2018 Mar 23. J Vet Intern Med. 2018. PMID: 29572958 Free PMC article. Clinical Trial.
HYPOTHESIS AND OBJECTIVES: Intravenous famotidine administered at 0.4 mg/kg will increase the pH of abomasal outflow digesta compared to saline control in adult cattle. The objectives were to assess the effect of famotidine, administered as a single dose and as mult …
HYPOTHESIS AND OBJECTIVES: Intravenous famotidine administered at 0.4 mg/kg will increase the pH of abomasal outflow digesta compared …
Effectiveness of oral famotidine in reducing the hematologic complications of radiotherapy in patients with esophageal and cardia cancers: a randomized controlled trial.
Rostami M, Yelghi O, Moghaddam ZK, Zeraatchi A, Rezaeejam H, Sadeghi A. Rostami M, et al. Radiat Oncol. 2023 May 20;18(1):83. doi: 10.1186/s13014-023-02281-w. Radiat Oncol. 2023. PMID: 37210511 Free PMC article. Clinical Trial.
The purpose of the present study was to examine the effectiveness of oral famotidine on the reduction of hematologic complications of patients with esophageal and gastric cardia cancers undergoing radiotherapy. ...The lymphocyte (P = 0.007) and platelet (P = 0.004) counts …
The purpose of the present study was to examine the effectiveness of oral famotidine on the reduction of hematologic complications of …
Low-dose famotidine and ranitidine as single post-prandial doses: a three-period placebo-controlled comparative trial.
Reilly TG, Singh S, Cottrell J, Mann SG, Stauffer L, Walt RP. Reilly TG, et al. Aliment Pharmacol Ther. 1996 Oct;10(5):749-55. doi: 10.1046/j.1365-2036.1996.50192000.x. Aliment Pharmacol Ther. 1996. PMID: 8899083 Clinical Trial.
METHODS: To investigate the relative abilities of low doses of famotidine and ranitidine to raise intragastric pH after a single post-prandial evening dose, 25 healthy volunteers completed a three-period cross-over trial of famotidine 10 mg, ranitidine elixir 75 mg …
METHODS: To investigate the relative abilities of low doses of famotidine and ranitidine to raise intragastric pH after a single post …
Pharmacodynamics and dose-response relationship of famotidine: a double-blind randomized placebo-controlled trial.
Laskin OL, Patterson PM, Shingo S, Lasseter KC, Shamblen EC. Laskin OL, et al. J Clin Pharmacol. 1993 Jul;33(7):636-9. doi: 10.1002/j.1552-4604.1993.tb04716.x. J Clin Pharmacol. 1993. PMID: 8366188 Clinical Trial.
Each subject received single oral administrations of famotidine 0.5, 2.5, 5.0, and 10.0 mg and placebo in a double-blind, randomized, cross-over fashion. ...There were no significant differences in mean pH seen between famotidine 0.5 mg versus placebo. The range of …
Each subject received single oral administrations of famotidine 0.5, 2.5, 5.0, and 10.0 mg and placebo in a double-blind, randomized, …
Comparison of the acid suppression effects between low-dose esomeprazole and famotidine in healthy subjects.
Kim HY, Hwang JG, Kim JW, Seong CH, Lee JH, Choi YS, Min HJ, Kim HS, Kim HY, Kim YK, Park MK. Kim HY, et al. Int J Clin Pharmacol Ther. 2023 Sep;61(9):377-385. doi: 10.5414/CP204391. Int J Clin Pharmacol Ther. 2023. PMID: 37382329 Clinical Trial.
OBJECTIVE: Famotidine, an H(2) receptor antagonist (H(2)RA), is mainly prescribed to alleviate the early symptoms of gastritis. ...For each period, the subjects were administered one dose of esomeprazole 10 mg or famotidine 20 mg or esomeprazole 20 mg each day. To e …
OBJECTIVE: Famotidine, an H(2) receptor antagonist (H(2)RA), is mainly prescribed to alleviate the early symptoms of gastritis. ...Fo …
Histamine H2-receptor antagonists.
Pounder R. Pounder R. Baillieres Clin Gastroenterol. 1988 Jul;2(3):593-608. doi: 10.1016/s0950-3528(88)80007-1. Baillieres Clin Gastroenterol. 1988. PMID: 2901868 Review.
546 results