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Gastroprotective efficacy and safety of single-tablet ibuprofen/famotidine vs ibuprofen in older persons.
Bello AE, Kent JD, Holt RJ. Bello AE, et al. Phys Sportsmed. 2015 Jul;43(3):193-9. doi: 10.1080/00913847.2015.1066229. Epub 2015 Jul 13. Phys Sportsmed. 2015. PMID: 26165391 Clinical Trial.
This analysis evaluated the gastroprotective efficacy and safety of the single-tablet combination of ibuprofen/famotidine compared with ibuprofen alone on the basis of age and the presence of one or more risk factors for development of upper GI ulcer. ...The …
This analysis evaluated the gastroprotective efficacy and safety of the single-tablet combination of ibuprofen/famotidine comp …
One-year open-label safety evaluation of the fixed combination of ibuprofen and famotidine with a prospective analysis of dyspepsia.
Bello AE, Kent JD, Grahn AY, Ball J, Holt RJ. Bello AE, et al. Curr Med Res Opin. 2015 Mar;31(3):397-405. doi: 10.1185/03007995.2014.999152. Epub 2015 Jan 9. Curr Med Res Opin. 2015. PMID: 25495134 Clinical Trial.
OBJECTIVE: To assess the long-term safety of the single-tablet combination of ibuprofen 800 mg and famotidine 26.6 mg. RESEARCH DESIGN AND METHODS: A phase 3b open-label study (NCT00984815) was conducted in 86 adults requiring daily non-steroidal anti-inflammatory d …
OBJECTIVE: To assess the long-term safety of the single-tablet combination of ibuprofen 800 mg and famotidine 26.6 mg. RESEARC …
One-year safety of ibuprofen/famotidine fixed combination versus ibuprofen alone: pooled analyses of two 24-week randomized, double-blind trials and a follow-on extension.
Bello AE, Grahn AY, Ball J, Kent JD, Holt RJ. Bello AE, et al. Curr Med Res Opin. 2015 Mar;31(3):407-20. doi: 10.1185/03007995.2014.1000086. Epub 2015 Jan 12. Curr Med Res Opin. 2015. PMID: 25516006 Clinical Trial.
Incidence of cardiovascular-related AEs of special interest were 11% (ibuprofen/famotidine) and 2% (ibuprofen) (p=0.06), possibly due to a higher number of rheumatoid arthritis patients in the combination group. Of these, 80% were reports of hypertension (8% …
Incidence of cardiovascular-related AEs of special interest were 11% (ibuprofen/famotidine) and 2% (ibuprofen) (p=0.06) …
Double-blind randomized trials of single-tablet ibuprofen/high-dose famotidine vs. ibuprofen alone for reduction of gastric and duodenal ulcers.
Laine L, Kivitz AJ, Bello AE, Grahn AY, Schiff MH, Taha AS. Laine L, et al. Am J Gastroenterol. 2012 Mar;107(3):379-86. doi: 10.1038/ajg.2011.443. Epub 2011 Dec 20. Am J Gastroenterol. 2012. PMID: 22186979 Free PMC article. Clinical Trial.
OBJECTIVES: We performed two 24-week double-blind trials (REDUCE-1 and -2 (Registration Endoscopic Studies to Determine Ulcer Formation of HZT-501 Compared with Ibuprofen: Efficacy and Safety Studies)) to assess whether double-dose famotidine given in a single-table …
OBJECTIVES: We performed two 24-week double-blind trials (REDUCE-1 and -2 (Registration Endoscopic Studies to Determine Ulcer Formation of H …
Acute phase response in patients undergoing lumbar spinal surgery: modulation by perioperative treatment with naproxen and famotidine.
Muñoz M, García-Vallejo JJ, Sempere JM, Romero R, Olalla E, Sebastián C. Muñoz M, et al. Eur Spine J. 2004 Jul;13(4):367-73. doi: 10.1007/s00586-003-0641-9. Epub 2003 Nov 21. Eur Spine J. 2004. PMID: 14634855 Free PMC article. Clinical Trial.
Accordingly, our objective was to investigate the effects of preoperative treatment with naproxen plus famotidine on the postoperative systemic inflammatory reaction in patients undergoing instrumented lumbar spinal surgery. ...In conclusion, perioperative treatment with n …
Accordingly, our objective was to investigate the effects of preoperative treatment with naproxen plus famotidine on the postoperativ …