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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1963 2
1964 37
1965 56
1966 55
1967 68
1968 80
1969 98
1970 72
1971 80
1972 71
1973 100
1974 108
1975 120
1976 110
1977 112
1978 128
1979 133
1980 153
1981 189
1982 216
1983 250
1984 273
1985 314
1986 355
1987 442
1988 428
1989 544
1990 551
1991 570
1992 595
1993 586
1994 624
1995 640
1996 613
1997 581
1998 621
1999 551
2000 597
2001 545
2002 546
2003 621
2004 675
2005 647
2006 637
2007 701
2008 616
2009 695
2010 766
2011 783
2012 769
2013 818
2014 874
2015 861
2016 890
2017 960
2018 968
2019 1131
2020 1191
2021 1199
2022 1324
2023 1322
2024 1513
2025 1689
2026 1088

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Search Results

32,497 results

Results by year

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Page 1
The anomalous pharmacology of fentanyl.
Kelly E, Sutcliffe K, Cavallo D, Ramos-Gonzalez N, Alhosan N, Henderson G. Kelly E, et al. Br J Pharmacol. 2023 Apr;180(7):797-812. doi: 10.1111/bph.15573. Epub 2021 Jul 2. Br J Pharmacol. 2023. PMID: 34030211 Free article. Review.
A number of factors have been suggested to contribute to fentanyl's lethality, including rapid onset of action, in vivo potency, ligand bias, induction of muscle rigidity and reduced sensitivity to reversal by naloxone. Some of these factors can be considered to rep …
A number of factors have been suggested to contribute to fentanyl's lethality, including rapid onset of action, in vivo potenc …
Fentanyl Absorption, Distribution, Metabolism, and Excretion: Narrative Review and Clinical Significance Related to Illicitly Manufactured Fentanyl.
Bird HE, Huhn AS, Dunn KE. Bird HE, et al. J Addict Med. 2023 Sep-Oct 01;17(5):503-508. doi: 10.1097/ADM.0000000000001185. Epub 2023 May 17. J Addict Med. 2023. PMID: 37788600 Free PMC article. Review.
OBJECTIVES: This narrative review summarizes literature on pharmaceutical fentanyl's absorption, distribution, metabolism, and excretion patterns to inform research on illicitly manufactured fentanyl (IMF). ...Fentanyl has a long terminal elimination, …
OBJECTIVES: This narrative review summarizes literature on pharmaceutical fentanyl's absorption, distribution, metabolism, and …
The fentanyl story.
Stanley TH. Stanley TH. J Pain. 2014 Dec;15(12):1215-26. doi: 10.1016/j.jpain.2014.08.010. J Pain. 2014. PMID: 25441689 Free article.
Fentanyl, introduced more than 50 years ago, has become the most often used opioid for intraoperative analgesia. ...The purpose of this article is to describe why this opioid has become so important in the treatment of pain in modern clinical practice. The data indicate th …
Fentanyl, introduced more than 50 years ago, has become the most often used opioid for intraoperative analgesia. ...The purpose of th …
Fentanyl Overdose.
Walter K. Walter K. JAMA. 2023 Jan 10;329(2):184. doi: 10.1001/jama.2022.22462. JAMA. 2023. PMID: 36459152
This JAMA Patient Page describes fentanyl and illicit fentanyl analogues, and the common signs and symptoms of fentanyl overdose, its treatment, and overdose prevention measures....
This JAMA Patient Page describes fentanyl and illicit fentanyl analogues, and the common signs and symptoms of fentanyl …
[Fentanyl].
Vestergaard SV, Nielsen AVA, Hollingdal M, Andersen CU, Bach A, Sædder EA, Krogh ML. Vestergaard SV, et al. Ugeskr Laeger. 2025 Aug 18;187(34):V01250023. doi: 10.61409/V01250023. Ugeskr Laeger. 2025. PMID: 40910385 Free article. Review. Danish.
Fentanyl is an opioid used for acute pain relief, but its slow elimination may lead to prolonged respiratory depression and sedation. As fatty tissue serves as fentanyl storage and prolongs its elimination, fentanyl should be dosed based on estimated ideal bo …
Fentanyl is an opioid used for acute pain relief, but its slow elimination may lead to prolonged respiratory depression and sedation. …
The rise of illicit fentanyls, stimulants and the fourth wave of the opioid overdose crisis.
Ciccarone D. Ciccarone D. Curr Opin Psychiatry. 2021 Jul 1;34(4):344-350. doi: 10.1097/YCO.0000000000000717. Curr Opin Psychiatry. 2021. PMID: 33965972 Free PMC article. Review.
RECENT FINDINGS: Overdose due to illicit synthetic opioids (e.g. fentanyl and fentanyl analogs) continues to rise in the US both preceding and during the COVID-19 pandemic. Fentanyl-related overdose is rising in new geographic areas e.g. the western USA. Stim …
RECENT FINDINGS: Overdose due to illicit synthetic opioids (e.g. fentanyl and fentanyl analogs) continues to rise in the US bo …
Caring for Hospitalized Adults With Opioid Use Disorder in the Era of Fentanyl: A Review.
Englander H, Thakrar AP, Bagley SM, Rolley T, Dong K, Hyshka E. Englander H, et al. JAMA Intern Med. 2024 Jun 1;184(6):691-701. doi: 10.1001/jamainternmed.2023.7282. JAMA Intern Med. 2024. PMID: 38683591 Review.
OBSERVATIONS: Clinical best practices include managing acute withdrawal and pain, initiating medication for OUD, integrating harm reduction principles and practices, addressing in-hospital substance use, and supporting hospital-to-community care transitions. Fentanyl compl …
OBSERVATIONS: Clinical best practices include managing acute withdrawal and pain, initiating medication for OUD, integrating harm reduction …
Fentanyl.
Stanley TH. Stanley TH. J Pain Symptom Manage. 2005 May;29(5 Suppl):S67-71. doi: 10.1016/j.jpainsymman.2005.01.009. J Pain Symptom Manage. 2005. PMID: 15907648 Free article.
Fentanyl, a potent lipid-soluble opioid which was first synthesized more than 40 years ago, is still the most popular opioid used in the perioperative period throughout the world. Fentanyl's introduction, versatility, and popularity have resulted in its use i …
Fentanyl, a potent lipid-soluble opioid which was first synthesized more than 40 years ago, is still the most popular opioid used in …
High-dose fentanyl.
[No authors listed] [No authors listed] Lancet. 1979 Jan;1(8107):81-2. Lancet. 1979. PMID: 84132 No abstract available.
Intravenous fentanyl kinetics.
McClain DA, Hug CC Jr. McClain DA, et al. Clin Pharmacol Ther. 1980 Jul;28(1):106-14. doi: 10.1038/clpt.1980.138. Clin Pharmacol Ther. 1980. PMID: 7389247
We examined fentanyl kinetics and excretion in 7 healthy male subjects who were given a 3.2- or 6.4-micrograms/kg dose of 3H-fentanyl intravenously. ...Eighty-five percent of the dose was recovered in urine and feces in 72 hr; less than 8% was recovered as unchanged …
We examined fentanyl kinetics and excretion in 7 healthy male subjects who were given a 3.2- or 6.4-micrograms/kg dose of 3H-fenta …
32,497 results
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