Why fexofenadine is considered as a truly non-sedating antihistamine with no brain penetration: a systematic review.
Ansotegui IJ, Bousquet J, Canonica GW, Demoly P, Gómez RM, Meltzer EO, Murrieta-Aguttes M, Naclerio RM, Rosario Filho N, Scadding GK.
Ansotegui IJ, et al.
Curr Med Res Opin. 2024 Aug;40(8):1297-1309. doi: 10.1080/03007995.2024.2378172. Epub 2024 Jul 19.
Curr Med Res Opin. 2024.
PMID: 39028636
Free article.
Results of brain H(1)-receptor occupancy (H(1)RO) obtained from PET showed no H(1)RO by fexofenadine, the receptor which is known to cause sedation of H(1) antihistamines. Most studies calculating PIR value as 0 showed fexofenadine to be a non-impairing oral antihis …
Results of brain H(1)-receptor occupancy (H(1)RO) obtained from PET showed no H(1)RO by fexofenadine, the receptor which is known to …