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457 results

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Page 1
Comparison of propofol vs. remimazolam on emergence profiles after general anesthesia: A randomized clinical trial.
Oh EJ, Chung YJ, Lee JH, Kwon EJ, Choi EA, On YK, Min JJ. Oh EJ, et al. J Clin Anesth. 2023 Nov;90:111223. doi: 10.1016/j.jclinane.2023.111223. Epub 2023 Jul 26. J Clin Anesth. 2023. PMID: 37506483 Clinical Trial.
STUDY OBJECTIVE: The emergence profiles in patients undergoing total intravenous anesthesia with either propofol or remimazolam with flumazenil reversal were compared. DESIGN: A prospective, double-blind, randomized trial. ...Further studies are needed to determine adequat …
STUDY OBJECTIVE: The emergence profiles in patients undergoing total intravenous anesthesia with either propofol or remimazolam with flum …
Clinical Study of Flumazenil Antagonizing Remimazolam on Nausea and Vomiting After Gynecologic Day Surgery.
Wei Y, Zhu M, Man Y, Xiao H, Dong G, Shi X, Ji F. Wei Y, et al. Drug Des Devel Ther. 2024 Mar 4;18:631-638. doi: 10.2147/DDDT.S444313. eCollection 2024. Drug Des Devel Ther. 2024. PMID: 38465267 Free PMC article. Clinical Trial.
PURPOSE: To evaluate the effect of flumazenil antagonizing remimazolam on postoperative nausea and vomiting (PONV) after gynecologic day surgery. ...Stopping the injection of remimazolam and alfentanil at the end of the operation. Flumazenil 0.2 mg was given to anta …
PURPOSE: To evaluate the effect of flumazenil antagonizing remimazolam on postoperative nausea and vomiting (PONV) after gynecologic …
Randomized clinical trial to assess the mPADSS scale in recovery and home discharge after endoscopy.
de Benito Sanz M, Martínez de la Torre S, Salvador de Las Heras MªA, Calleja Carbajosa R, Sesma Fernández PV, Pérez Sierra L, García-Alonso FJ, Perez-Miranda M. de Benito Sanz M, et al. Rev Esp Enferm Dig. 2020 Oct;112(10):762-767. doi: 10.17235/reed.2020.6420/2019. Rev Esp Enferm Dig. 2020. PMID: 32954768 Free article. Clinical Trial.
An average of 160 mg of propofol was required per patient, with additional flumazenil and midazolam in 49. There were two episodes of vomiting and three of mild desaturation, all of them in the control group. ...
An average of 160 mg of propofol was required per patient, with additional flumazenil and midazolam in 49. There were two episodes of …
Flumazenil in benzodiazepine antagonism. Actions and clinical use in intoxications and anaesthesiology.
Amrein R, Leishman B, Bentzinger C, Roncari G. Amrein R, et al. Med Toxicol Adverse Drug Exp. 1987 Nov-Dec;2(6):411-29. doi: 10.1007/BF03259876. Med Toxicol Adverse Drug Exp. 1987. PMID: 2893240 Review.
After intoxication with high benzodiazepine doses, the duration of effect of a single dose of flumazenil is not expected to exceed 1 hour. In such cases, the period of wakefulness can be prolonged as necessary by repeated low intravenous doses of flumazenil or by in …
After intoxication with high benzodiazepine doses, the duration of effect of a single dose of flumazenil is not expected to exceed 1 …
Efficacy and safety of remimazolam tosilate versus propofol in patients undergoing day surgery: a prospective randomized controlled trial.
Luo W, Sun M, Wan J, Zhang Z, Huang J, Zhang J, Xiong W, Xia L, Xu P, Miao C, Zhang X, Liu M, Zhong J. Luo W, et al. BMC Anesthesiol. 2023 May 26;23(1):182. doi: 10.1186/s12871-023-02092-2. BMC Anesthesiol. 2023. PMID: 37237331 Free PMC article. Clinical Trial.
This study aimed to assess the efficacy and safety of RT with or without flumazenil compared with propofol in general anesthesia for day surgery. METHODS: 115 patients scheduled for day surgery were randomized into three groups: RT (n = 39), RT + flumazenil (n = 38) …
This study aimed to assess the efficacy and safety of RT with or without flumazenil compared with propofol in general anesthesia for …
Remimazolam-flumazenil provides fast recovery from general anesthesia compared to propofol during radiofrequency catheter ablation of atrial fibrillation.
Lee S, Lee J, Hwang SY, Ju JW, Nam K, Ahn HJ, Lee SR, Choi EK, Jeon Y, Cho YJ. Lee S, et al. Sci Rep. 2024 Jun 3;14(1):12660. doi: 10.1038/s41598-024-63578-8. Sci Rep. 2024. PMID: 38831029 Free PMC article. Clinical Trial.
We compared the recovery and hemodynamic parameters between the remimazolam-flumazenil and propofol groups during RFCA. Patients were randomized into the remimazolam-flumazenil and propofol groups. ...Fifty-three patients were included in the final analysis (n = 26 …
We compared the recovery and hemodynamic parameters between the remimazolam-flumazenil and propofol groups during RFCA. Patients were …
Prospective Randomized Controlled Trial Comparing Anesthetic Management With Remimazolam Besylate and Flumazenil Versus Propofol During Awake Craniotomy Following an Asleep-awake-asleep Method.
Sato T, Ando T, Ozeki K, Asano I, Kuwatsuka Y, Ando M, Motomura K, Nishiwaki K. Sato T, et al. J Neurosurg Anesthesiol. 2025 Jan 1;37(1):40-46. doi: 10.1097/ANA.0000000000000975. Epub 2024 Jun 5. J Neurosurg Anesthesiol. 2025. PMID: 38836295 Clinical Trial.
METHODS: In a single-institution randomized, prospective study, patients who underwent elective awake craniotomy were randomized to receive remimazolam and reversal with flumazenil (group R) or propofol (group P). The primary end point was time to awaken. Secondary end poi …
METHODS: In a single-institution randomized, prospective study, patients who underwent elective awake craniotomy were randomized to receive …
Flumazenil: US clinical pharmacology studies.
Dunton AW, Schwam E, Pitman V, McGrath J, Hendler J, Siegel J. Dunton AW, et al. Eur J Anaesthesiol Suppl. 1988;2:81-95. Eur J Anaesthesiol Suppl. 1988. PMID: 2842144 Review.
Flumazenil, a benzodiazepine antagonist, blocks the central effects of benzodiazepines by competitive interaction at the receptor site. ...Assessment of sedation, psychomotor performance and recall/recognition were made both before and after the benzodiazepine as well as s …
Flumazenil, a benzodiazepine antagonist, blocks the central effects of benzodiazepines by competitive interaction at the receptor sit …
Comparison of Remimazolam-Flumazenil and Propofol on Psychomotor Function and Emergence Following General Anesthesia in Surgical Abortion: A Randomized Controlled Trial.
Gu J, Liu Y, Lin X, Fu L, Liu J, Sun B, Li X, Lu B. Gu J, et al. Drug Des Devel Ther. 2024 Dec 30;18:6447-6457. doi: 10.2147/DDDT.S486892. eCollection 2024. Drug Des Devel Ther. 2024. PMID: 39758228 Free PMC article. Clinical Trial.
OBJECTIVE: This study aims to compare the recovery profiles of remimazolam combined with flumazenil against those of propofol in patients undergoing painless surgical abortion, focusing on psychomotor function and emergence. ...CONCLUSION: Remimazolam combined with flum …
OBJECTIVE: This study aims to compare the recovery profiles of remimazolam combined with flumazenil against those of propofol in pati …
Comparison of the recovery time of remimazolam besylate and propofol for gastrointestinal endoscopy sedation in elderly patients.
Chen HY, Wang XX, Lu YG, Tang SH, Ding T, Song JC, Chen G. Chen HY, et al. Int J Med Sci. 2024 May 13;21(7):1250-1256. doi: 10.7150/ijms.93045. eCollection 2024. Int J Med Sci. 2024. PMID: 38818475 Free PMC article. Clinical Trial.
Conclusion: Our study demonstrated that remimazolam anesthesia combined with flumazenil antagonism causes a shorter recovery time for elderly patients undergoing gastrointestinal endoscopy compared to propofol. Remimazolam followed by flumazenil antagonism provides …
Conclusion: Our study demonstrated that remimazolam anesthesia combined with flumazenil antagonism causes a shorter recovery time for …
457 results