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Year Number of Results
1981 1
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1983 3
1984 4
1985 4
1986 8
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1988 31
1989 20
1990 41
1991 28
1992 22
1993 18
1994 23
1995 20
1996 23
1997 14
1998 13
1999 14
2000 14
2001 9
2002 10
2003 10
2004 9
2005 10
2006 8
2007 3
2008 6
2009 7
2010 9
2011 11
2012 12
2013 7
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2015 3
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2017 3
2018 1
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2020 3
2021 2
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433 results
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Page 1
Psychomotor Recovery Following Remimazolam-induced Sedation and the Effectiveness of Flumazenil as an Antidote.
Chen X, Sang N, Song K, Zhong W, Wang H, Jiang J, Huang Y, Hu P. Chen X, et al. Clin Ther. 2020 Apr;42(4):614-624. doi: 10.1016/j.clinthera.2020.02.006. Epub 2020 Mar 13. Clin Ther. 2020. PMID: 32178858 Clinical Trial.
FINDINGS: After bolus infusion, the Bispectral Index score decreased in a concentration-dependent manner with HR-7056, accompanied by a sharp drop of Modified Observer's Assessment of Alertness/Sedation score. The recovery of consciousness was much faster with HR-7056 than …
FINDINGS: After bolus infusion, the Bispectral Index score decreased in a concentration-dependent manner with HR-7056, accompanied by a shar …
Randomized clinical trial to assess the mPADSS scale in recovery and home discharge after endoscopy.
de Benito Sanz M, Martínez de la Torre S, Salvador de Las Heras MªA, Calleja Carbajosa R, Sesma Fernández PV, Pérez Sierra L, García-Alonso FJ, Perez-Miranda M. de Benito Sanz M, et al. Rev Esp Enferm Dig. 2020 Oct;112(10):762-767. doi: 10.17235/reed.2020.6420/2019. Rev Esp Enferm Dig. 2020. PMID: 32954768 Free article. Clinical Trial.
An average of 160 mg of propofol was required per patient, with additional flumazenil and midazolam in 49. There were two episodes of vomiting and three of mild desaturation, all of them in the control group. ...
An average of 160 mg of propofol was required per patient, with additional flumazenil and midazolam in 49. There were two episodes of …
Flumazenil in benzodiazepine antagonism. Actions and clinical use in intoxications and anaesthesiology.
Amrein R, Leishman B, Bentzinger C, Roncari G. Amrein R, et al. Med Toxicol Adverse Drug Exp. 1987 Nov-Dec;2(6):411-29. doi: 10.1007/BF03259876. Med Toxicol Adverse Drug Exp. 1987. PMID: 2893240 Review.
After intoxication with high benzodiazepine doses, the duration of effect of a single dose of flumazenil is not expected to exceed 1 hour. In such cases, the period of wakefulness can be prolonged as necessary by repeated low intravenous doses of flumazenil or by in …
After intoxication with high benzodiazepine doses, the duration of effect of a single dose of flumazenil is not expected to exceed 1 …
Flumazenil: a benzodiazepine antagonist.
Karavokiros KA, Tsipis GB. Karavokiros KA, et al. DICP. 1990 Oct;24(10):976-81. doi: 10.1177/106002809002401013. DICP. 1990. PMID: 2244412 Review.
Flumazenil's short duration of activity is due to its rapid hepatic metabolism and elimination. ...Flumazenil appears to provide a mechanism for the safe and effective reversal of benzodiazepine-induced sedation....
Flumazenil's short duration of activity is due to its rapid hepatic metabolism and elimination. ...Flumazenil appears t …
Anesthesia of growing pigs with tiletamine-zolazepam and reversal with flumazenil.
Lee JY, Kim MC. Lee JY, et al. J Vet Med Sci. 2012 Mar;74(3):335-9. doi: 10.1292/jvms.10-0501. Epub 2011 Nov 8. J Vet Med Sci. 2012. PMID: 22067078 Free article. Clinical Trial.
The aim of the present study was to evaluate the anesthetic and cardiorespiratory effects of tiletamine/zolazepam and the effect of flumazenil on the recovery from tiletamine/zolazepam anesthesia in the pig. ...The anesthetic effects induced by tiletamine/zolazepam could b …
The aim of the present study was to evaluate the anesthetic and cardiorespiratory effects of tiletamine/zolazepam and the effect of fluma …
Reduction of aggression during benzodiazepine withdrawal: effects of flumazenil.
Saxon L, Borg S, Hiltunen AJ. Saxon L, et al. Pharmacol Biochem Behav. 2010 Aug;96(2):148-51. doi: 10.1016/j.pbb.2010.04.023. Epub 2010 May 6. Pharmacol Biochem Behav. 2010. PMID: 20451546 Clinical Trial.
The aim was to analyze the effects of flumazenil on hostility and aggression. Ten patients and 10 controls received, on two separate occasions, cumulative doses of flumazenil (0.05, 0.1, 0.25, 0.5 and 1mg at 15min intervals) or placebo. ...The results suggest that s …
The aim was to analyze the effects of flumazenil on hostility and aggression. Ten patients and 10 controls received, on two separate …
Flumazenil: US clinical pharmacology studies.
Dunton AW, Schwam E, Pitman V, McGrath J, Hendler J, Siegel J. Dunton AW, et al. Eur J Anaesthesiol Suppl. 1988;2:81-95. Eur J Anaesthesiol Suppl. 1988. PMID: 2842144 Review.
Flumazenil, a benzodiazepine antagonist, blocks the central effects of benzodiazepines by competitive interaction at the receptor site. ...Assessment of sedation, psychomotor performance and recall/recognition were made both before and after the benzodiazepine as well as s …
Flumazenil, a benzodiazepine antagonist, blocks the central effects of benzodiazepines by competitive interaction at the receptor sit …
A randomised, controlled trial of cognitive and psychomotor recovery from midazolam sedation following reversal with oral flumazenil.
Girdler NM, Lyne JP, Wallace R, Neave N, Scholey A, Wesnes KA, Herman C. Girdler NM, et al. Anaesthesia. 2002 Sep;57(9):868-76. doi: 10.1046/j.1365-2044.2002.02785.x. Anaesthesia. 2002. PMID: 12190751 Free article. Clinical Trial.
Flumazenil is traditionally administered intravenously to reverse the adverse effects of over sedation with benzodiazepines. The aim of this study was to test postoperative cognitive and psychomotor recovery from midazolam conscious sedation, following reversal with orally …
Flumazenil is traditionally administered intravenously to reverse the adverse effects of over sedation with benzodiazepines. The aim …
Flumazenil reversal of sublingual triazolam: a randomized controlled clinical trial.
Hosaka K, Jackson D, Pickrell JE, Heima M, Milgrom P. Hosaka K, et al. J Am Dent Assoc. 2009 May;140(5):559-66. doi: 10.14219/jada.archive.2009.0226. J Am Dent Assoc. 2009. PMID: 19411525 Free PMC article. Clinical Trial.
The authors assessed outcomes by using the Observer's Assessment of Alertness/Sedation (OAA/S) scale, bispectral index (BIS) and physiological monitoring. RESULTS: The OAA/S and BIS scores increased after the flumazenil injection at the 30-minute obser …
The authors assessed outcomes by using the Observer's Assessment of Alertness/Sedation (OAA/S) scale, bispectral index (BIS) a …
Flumazenil improves cognitive and neuromotor emergence and attenuates shivering after halothane-, enflurane- and isoflurane-based anesthesia.
Weinbroum AA, Geller E. Weinbroum AA, et al. Can J Anaesth. 2001 Nov;48(10):963-72. doi: 10.1007/BF03016585. Can J Anaesth. 2001. PMID: 11698314 Clinical Trial.
Reversal of amnesia was superior in the flumazenil group at 60 min and at 24 hr postsurgery, and more flumazenil patients rated recovery as "pleasant". Flumazenil patients shivered less than placebo patients despite their lower core temperature (at 30 min: ha …
Reversal of amnesia was superior in the flumazenil group at 60 min and at 24 hr postsurgery, and more flumazenil patients rate …
433 results