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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1965 2
1966 4
1967 4
1968 12
1969 19
1970 19
1971 27
1972 45
1973 27
1974 8
1975 13
1976 16
1977 16
1978 32
1979 15
1980 9
1981 11
1982 20
1983 17
1984 18
1985 21
1986 22
1987 22
1988 41
1989 38
1990 44
1991 69
1992 95
1993 106
1994 130
1995 157
1996 136
1997 130
1998 146
1999 169
2000 167
2001 173
2002 196
2003 193
2004 240
2005 238
2006 239
2007 266
2008 242
2009 244
2010 226
2011 226
2012 235
2013 220
2014 210
2015 245
2016 233
2017 213
2018 192
2019 207
2020 210
2021 152
2022 135
2023 108
2024 27

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6,113 results

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Page 1
Effect of Folic Acid and Zinc Supplementation in Men on Semen Quality and Live Birth Among Couples Undergoing Infertility Treatment: A Randomized Clinical Trial.
Schisterman EF, Sjaarda LA, Clemons T, Carrell DT, Perkins NJ, Johnstone E, Lamb D, Chaney K, Van Voorhis BJ, Ryan G, Summers K, Hotaling J, Robins J, Mills JL, Mendola P, Chen Z, DeVilbiss EA, Peterson CM, Mumford SL. Schisterman EF, et al. JAMA. 2020 Jan 7;323(1):35-48. doi: 10.1001/jama.2019.18714. JAMA. 2020. PMID: 31910279 Free PMC article. Clinical Trial.
DESIGN, SETTING, AND PARTICIPANTS: The Folic Acid and Zinc Supplementation Trial was a multicenter randomized clinical trial. ...A statistically significant increase in DNA fragmentation was observed with folic acid and zinc supplementation (mean of 29 …
DESIGN, SETTING, AND PARTICIPANTS: The Folic Acid and Zinc Supplementation Trial was a multicenter randomized clinical trial. …
Effects of maternal folic acid supplementation during the second and third trimesters of pregnancy on neurocognitive development in the child: an 11-year follow-up from a randomised controlled trial.
Caffrey A, McNulty H, Rollins M, Prasad G, Gaur P, Talcott JB, Witton C, Cassidy T, Marshall B, Dornan J, Moore AJ, Ward M, Strain JJ, Molloy AM, McLaughlin M, Lees-Murdock DJ, Walsh CP, Pentieva K. Caffrey A, et al. BMC Med. 2021 Mar 10;19(1):73. doi: 10.1186/s12916-021-01914-9. BMC Med. 2021. PMID: 33750355 Free PMC article. Clinical Trial.
BACKGROUND: Maternal folic acid (FA) supplementation before and in early pregnancy prevents neural tube defects (NTD), but it is uncertain whether continuing FA after the first trimester has benefits on offspring health. ...METHODS: Follow-up investigation of 11-yea …
BACKGROUND: Maternal folic acid (FA) supplementation before and in early pregnancy prevents neural tube defects (NTD), but it …
Efficacy of folic acid therapy in primary prevention of stroke among adults with hypertension in China: the CSPPT randomized clinical trial.
Huo Y, Li J, Qin X, Huang Y, Wang X, Gottesman RF, Tang G, Wang B, Chen D, He M, Fu J, Cai Y, Shi X, Zhang Y, Cui Y, Sun N, Li X, Cheng X, Wang J, Yang X, Yang T, Xiao C, Zhao G, Dong Q, Zhu D, Wang X, Ge J, Zhao L, Hu D, Liu L, Hou FF; CSPPT Investigators. Huo Y, et al. JAMA. 2015 Apr 7;313(13):1325-35. doi: 10.1001/jama.2015.2274. JAMA. 2015. PMID: 25771069 Clinical Trial.
IMPORTANCE: Uncertainty remains about the efficacy of folic acid therapy for the primary prevention of stroke because of limited and inconsistent data. ...RESULTS: During a median treatment duration of 4.5 years, compared with the enalapril alone group, the enalapri …
IMPORTANCE: Uncertainty remains about the efficacy of folic acid therapy for the primary prevention of stroke because of limit …
Effect of continued folic acid supplementation beyond the first trimester of pregnancy on cognitive performance in the child: a follow-up study from a randomized controlled trial (FASSTT Offspring Trial).
McNulty H, Rollins M, Cassidy T, Caffrey A, Marshall B, Dornan J, McLaughlin M, McNulty BA, Ward M, Strain JJ, Molloy AM, Lees-Murdock DJ, Walsh CP, Pentieva K. McNulty H, et al. BMC Med. 2019 Oct 31;17(1):196. doi: 10.1186/s12916-019-1432-4. BMC Med. 2019. PMID: 31672132 Free PMC article. Clinical Trial.
BACKGROUND: Periconceptional folic acid prevents neural tube defects (NTDs), but it is uncertain whether there are benefits for offspring neurodevelopment arising from continued maternal folic acid supplementation beyond the first trimester. We investi …
BACKGROUND: Periconceptional folic acid prevents neural tube defects (NTDs), but it is uncertain whether there are benefits fo …
Folic Acid Supplementation Mitigates Alzheimer's Disease by Reducing Inflammation: A Randomized Controlled Trial.
Chen H, Liu S, Ji L, Wu T, Ji Y, Zhou Y, Zheng M, Zhang M, Xu W, Huang G. Chen H, et al. Mediators Inflamm. 2016;2016:5912146. doi: 10.1155/2016/5912146. Epub 2016 Jun 2. Mediators Inflamm. 2016. PMID: 27340344 Free PMC article. Clinical Trial.
Both phenomena have been linked to Alzheimer's disease (AD), but the effect of folic acid on AD itself is unclear. We quantified folate supplementation's effect on inflammation and cognitive function in patients with AD over the course of 6 months. ...The Abeta 42/A …
Both phenomena have been linked to Alzheimer's disease (AD), but the effect of folic acid on AD itself is unclear. We quantifi …
Prevention of neural tube defects: results of the Medical Research Council Vitamin Study. MRC Vitamin Study Research Group.
[No authors listed] [No authors listed] Lancet. 1991 Jul 20;338(8760):131-7. Lancet. 1991. PMID: 1677062 Clinical Trial.
A total of 1817 women at high risk of having a pregnancy with a neural tube defect, because of a previous affected pregnancy, were allocated at random to one of four groups--namely, folic acid, other vitamins, both, or neither. 1195 had a completed pregnancy in whic …
A total of 1817 women at high risk of having a pregnancy with a neural tube defect, because of a previous affected pregnancy, were allocated …
Iron and folic acid consumption and changing social norms: cluster randomized field trial, Odisha, India.
Rimal RN, Yilma H, Sedlander E, Mohanty S, Patro L, Pant I, Khuntia SK, Swain M, Behera S. Rimal RN, et al. Bull World Health Organ. 2021 Nov 1;99(11):773-782. doi: 10.2471/BLT.20.278820. Epub 2021 Aug 31. Bull World Health Organ. 2021. PMID: 34737470 Free PMC article. Clinical Trial.
OBJECTIVE: To assess whether improvements in social norms related to iron and folic acid consumption are associated with increased iron and folic acid consumption. METHODS: In a cluster randomized trial in Odisha, India, we implemented an intervention …
OBJECTIVE: To assess whether improvements in social norms related to iron and folic acid consumption are associated with incre …
A placebo-controlled trial of folic acid and betaine in identical twins with Angelman syndrome.
Han J, Bichell TJ, Golden S, Anselm I, Waisbren S, Bacino CA, Peters SU, Bird LM, Kimonis V. Han J, et al. Orphanet J Rare Dis. 2019 Oct 22;14(1):232. doi: 10.1186/s13023-019-1216-0. Orphanet J Rare Dis. 2019. PMID: 31640736 Free PMC article. Clinical Trial.
We treated two sets of male identical twins with class I deletions with a 1 year treatment trial of either betaine and folic acid versus placebo. We found no statistically significant changes in the clinical parameters tested at the end of the 1 year trial, nor did …
We treated two sets of male identical twins with class I deletions with a 1 year treatment trial of either betaine and folic acid
Folic acid supplementation and risk of colorectal neoplasia during long-term follow-up of a randomized clinical trial.
Passarelli MN, Barry EL, Rees JR, Mott LA, Zhang D, Ahnen DJ, Bresalier RS, Haile RW, McKeown-Eyssen G, Snover DC, Cole BF, Baron JA. Passarelli MN, et al. Am J Clin Nutr. 2019 Oct 1;110(4):903-911. doi: 10.1093/ajcn/nqz160. Am J Clin Nutr. 2019. PMID: 31401653 Free PMC article. Clinical Trial.
OBJECTIVE: We conducted secondary analyses to evaluate folic acid effects with additional follow-up after treatment was stopped. ...CONCLUSIONS: Delayed treatment effects were not observed, but folic acid may increase SSA/P risk. This trial was registe …
OBJECTIVE: We conducted secondary analyses to evaluate folic acid effects with additional follow-up after treatment was stoppe …
Folic acid and vitamin B12 supplementation in subjects with type 2 diabetes mellitus: A multi-arm randomized controlled clinical trial.
Satapathy S, Bandyopadhyay D, Patro BK, Khan S, Naik S. Satapathy S, et al. Complement Ther Med. 2020 Sep;53:102526. doi: 10.1016/j.ctim.2020.102526. Epub 2020 Jul 22. Complement Ther Med. 2020. PMID: 33066869 Clinical Trial.
OBJECTIVE: This study was conducted to investigate and compare the effects of add-on folic acid and vitamin B12 supplementation on glycaemic control, insulin resistance and serum lipid profile in subjects with type 2 diabetes mellitus. STUDY DESIGN & INTERVENTIO …
OBJECTIVE: This study was conducted to investigate and compare the effects of add-on folic acid and vitamin B12 supplementatio …
6,113 results