Effect of Folic Acid and Zinc Supplementation in Men on Semen Quality and Live Birth Among Couples Undergoing Infertility Treatment: A Randomized Clinical Trial.
JAMA. 2020 Jan 7;323(1):35-48. doi: 10.1001/jama.2019.18714.
JAMA. 2020.
PMID: 31910279
Free PMC article.
Clinical Trial.
DESIGN, SETTING, AND PARTICIPANTS: The Folic Acid and Zinc Supplementation Trial was a multicenter randomized clinical trial. ...A statistically significant increase in DNA fragmentation was observed with folic acid and zinc supplementation (mean of 29 …
DESIGN, SETTING, AND PARTICIPANTS: The Folic Acid and Zinc Supplementation Trial was a multicenter randomized clinical trial. …