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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1965 3
1966 2
1967 2
1968 4
1969 4
1970 6
1971 3
1972 6
1973 4
1974 5
1975 7
1976 12
1977 13
1978 28
1979 23
1980 19
1981 31
1982 37
1983 42
1984 39
1985 56
1986 67
1987 107
1988 118
1989 125
1990 163
1991 195
1992 194
1993 186
1994 251
1995 263
1996 272
1997 268
1998 271
1999 243
2000 274
2001 236
2002 234
2003 259
2004 275
2005 250
2006 246
2007 278
2008 237
2009 239
2010 273
2011 233
2012 231
2013 251
2014 237
2015 246
2016 219
2017 192
2018 177
2019 186
2020 178
2021 173
2022 209
2023 63

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7,966 results

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Page 1
Influence of St. John's Wort on Intravenous Fentanyl Pharmacokinetics, Pharmacodynamics, and Clinical Effects: A Randomized Clinical Trial.
Loughren MJ, Kharasch ED, Kelton-Rehkopf MC, Syrjala KL, Shen DD. Loughren MJ, et al. Anesthesiology. 2020 Mar;132(3):491-503. doi: 10.1097/ALN.0000000000003065. Anesthesiology. 2020. PMID: 31794512 Free PMC article. Clinical Trial.
RESULTS: St. John's wort did not alter fentanyl pharmacokinetics. Clearance (l/min) before and after St. ...St. John's wort also did not affect fentanyl pharmacodynamics as measured by pupil constriction after fixed-dose and tailored fentanyl in …
RESULTS: St. John's wort did not alter fentanyl pharmacokinetics. Clearance (l/min) before and after St. ...St. John's …
Polymorphisms associated with fentanyl pharmacokinetics, pharmacodynamics and adverse effects.
Saiz-Rodríguez M, Ochoa D, Herrador C, Belmonte C, Román M, Alday E, Koller D, Zubiaur P, Mejía G, Hernández-Martínez M, Abad-Santos F. Saiz-Rodríguez M, et al. Basic Clin Pharmacol Toxicol. 2019 Mar;124(3):321-329. doi: 10.1111/bcpt.13141. Epub 2018 Oct 30. Basic Clin Pharmacol Toxicol. 2019. PMID: 30281924 Free article. Clinical Trial.
In order to study whether pharmacogenetics explains some of the variability in the response to fentanyl, several genes related to fentanyl receptors, transporters and metabolic enzymes have been analysed. ...CYP3A5*3, ABCB1 C3435T and ABCB1 G2677T/A were not associa …
In order to study whether pharmacogenetics explains some of the variability in the response to fentanyl, several genes related to …
Spinal and epidural sufentanil and fentanyl in early labour.
Väänänen A, Kuukasjärvi M, Tekay A, Ahonen J. Väänänen A, et al. Acta Anaesthesiol Scand. 2019 Nov;63(10):1413-1418. doi: 10.1111/aas.13450. Epub 2019 Jul 23. Acta Anaesthesiol Scand. 2019. PMID: 31286476 Clinical Trial.

At 20 minutes after spinal sufentanil, epidural sufentanil, spinal fentanyl or epidural fentanyl, the maximum VAS was 19 (7-31), 45 (32-59), 25 (10-39) or 52 (40-63) mm, respectively (P < .01 spin vs epid groups). There were no differences in efficacy between spi

…
At 20 minutes after spinal sufentanil, epidural sufentanil, spinal fentanyl or epidural fentanyl, the maximum VAS was 19 (7-31 …
Use of TTS fentanyl as a single opioid for cancer pain relief: a safety and efficacy clinical trial in patients naive to mild or strong opioids.
Mystakidou K, Befon S, Tsilika E, Dardoufas K, Georgaki S, Vlahos L. Mystakidou K, et al. Oncology. 2002;62(1):9-16. doi: 10.1159/000048241. Oncology. 2002. PMID: 11810038 Clinical Trial.
BACKGROUND: Up to now, a transdermal therapeutic system (TTS) of fentanyl has been applied to cancer patients on opioid analgesics previously treated with mild opioids or morphine. ...Data assessments were made at baseline, on days 1, 2 and 3 (during hospitalization) and t …
BACKGROUND: Up to now, a transdermal therapeutic system (TTS) of fentanyl has been applied to cancer patients on opioid analgesics pr …
Pharmacokinetics and safety of fentanyl sublingual spray and fentanyl citrate intravenous: a multiple ascending dose study in opioid-naïve healthy volunteers.
Rauck RL, Oh DA, Singla N, Koch C, Parikh N, Nalamachu S, Wilson D, Yu J, Vetticaden S. Rauck RL, et al. Curr Med Res Opin. 2017 Nov;33(11):1921-1933. doi: 10.1080/03007995.2017.1371681. Epub 2017 Sep 23. Curr Med Res Opin. 2017. PMID: 28942715 Clinical Trial.
Eight subjects in each cohort were randomly assigned (six subjects received fentanyl sublingual spray; two subjects received fentanyl citrate IV). ...Overall, the reported adverse events were consistent with the known safety profile of fentanyl. CONCLUSION: …
Eight subjects in each cohort were randomly assigned (six subjects received fentanyl sublingual spray; two subjects received fenta …
Pharmacokinetics and safety of fentanyl sublingual spray and fentanyl citrate intravenous: a single ascending dose study in opioid-naïve healthy volunteers.
Rauck R, Oh DA, Parikh N, Koch C, Singla N, Yu J, Nalamachu S, Vetticaden S. Rauck R, et al. Curr Med Res Opin. 2017 Nov;33(11):1915-1920. doi: 10.1080/03007995.2017.1352496. Epub 2017 Aug 11. Curr Med Res Opin. 2017. PMID: 28681626 Clinical Trial.
This study evaluated single-dose fentanyl sublingual spray in opioid-naive participants. RESEARCH DESIGN: Participants were randomized to receive single-dose fentanyl sublingual spray (100, 200, 400, 600, 800 mcg) or fentanyl citrate IV in one of five cohorts …
This study evaluated single-dose fentanyl sublingual spray in opioid-naive participants. RESEARCH DESIGN: Participants were randomize …
Transdermal fentanyl: pharmacokinetics and preliminary clinical evaluation.
Plezia PM, Kramer TH, Linford J, Hameroff SR. Plezia PM, et al. Pharmacotherapy. 1989;9(1):2-9. doi: 10.1002/j.1875-9114.1989.tb04096.x. Pharmacotherapy. 1989. PMID: 2646620 Clinical Trial.
The apparent elimination of fentanyl after transdermal administration is prolonged relative to previously reported values. ...Four patients required no additional analgesia. No consistent correlations among fentanyl concentration and any clinical values were observe …
The apparent elimination of fentanyl after transdermal administration is prolonged relative to previously reported values. ...Four pa …
Absolute and relative bioavailability of fentanyl buccal tablet and oral transmucosal fentanyl citrate.
Darwish M, Kirby M, Robertson P Jr, Tracewell W, Jiang JG. Darwish M, et al. J Clin Pharmacol. 2007 Mar;47(3):343-50. doi: 10.1177/0091270006297749. J Clin Pharmacol. 2007. PMID: 17322146 Clinical Trial.
This study assessed the absolute and relative bioavailabilities and transmucosal and gastrointestinal absorbency of fentanyl buccal tablet (FBT) and oral transmucosal fentanyl citrate (OTFC). ...More fentanyl was absorbed transmucosally from FBT than OTFC (48 …
This study assessed the absolute and relative bioavailabilities and transmucosal and gastrointestinal absorbency of fentanyl buccal t …
Subarachnoid morphine and fentanyl for labor analgesia. Efficacy and adverse effects.
Caldwell LE, Rosen MA, Shnider SM. Caldwell LE, et al. Reg Anesth. 1994 Jan-Feb;19(1):2-8. Reg Anesth. 1994. PMID: 8148291 Clinical Trial.
Furthermore, the combination of subarachnoid morphine and fentanyl proved ineffective in providing adequate pain relief for the duration of labor and delivery for the majority of patients. The authors recommend that subarachnoid morphine and fentanyl serve a limited …
Furthermore, the combination of subarachnoid morphine and fentanyl proved ineffective in providing adequate pain relief for the durat …
Alfentanil and recovery.
Sinclair ME, Cooper GM. Sinclair ME, et al. Anaesthesia. 1983 May;38(5):435-7. doi: 10.1111/j.1365-2044.1983.tb14025.x. Anaesthesia. 1983. PMID: 6134481 Free article. Clinical Trial.
7,966 results