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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1976 26
1978 3
1979 3
1980 4
1981 4
1982 12
1983 14
1984 9
1985 12
1986 17
1987 25
1988 40
1989 35
1990 62
1991 58
1992 49
1993 68
1994 55
1995 68
1996 71
1997 56
1998 64
1999 55
2000 62
2001 102
2002 103
2003 76
2004 72
2005 71
2006 77
2007 77
2008 77
2009 85
2010 79
2011 81
2012 76
2013 64
2014 61
2015 72
2016 69
2017 61
2018 70
2019 71
2020 57
2021 54
2022 50
2023 24
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2,305 results
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Page 1
Role of gemfibrozil as an inhibitor of CYP2C8 and membrane transporters.
Tornio A, Neuvonen PJ, Niemi M, Backman JT. Tornio A, et al. Expert Opin Drug Metab Toxicol. 2017 Jan;13(1):83-95. doi: 10.1080/17425255.2016.1227791. Epub 2016 Aug 31. Expert Opin Drug Metab Toxicol. 2017. PMID: 27548563 Review.
This effect is due to mechanism-based inhibition of CYP2C8 by gemfibrozil 1-O-beta-glucuronide. In vivo, gemfibrozil is a fairly selective CYP2C8 inhibitor, which lacks significant inhibitory effect on other CYP enzymes. ...Moreover, gemfibrozil could be used …
This effect is due to mechanism-based inhibition of CYP2C8 by gemfibrozil 1-O-beta-glucuronide. In vivo, gemfibrozil is a fair …
Gemfibrozil.
[No authors listed] [No authors listed] IARC Monogr Eval Carcinog Risks Hum. 1996;66:427-44. IARC Monogr Eval Carcinog Risks Hum. 1996. PMID: 9097130 Free PMC article. Review. No abstract available.
Gemfibrozil-induced myopathy.
Magarian GJ, Lucas LM, Colley C. Magarian GJ, et al. Arch Intern Med. 1991 Sep;151(9):1873-4. Arch Intern Med. 1991. PMID: 1888257 Review.
A particularly severe form, often accompanied by rhabdomyolysis, has been reported with the use of lovastatin and gemfibrozil; however, as far as we know, no case has been documented with use of gemfibrozil alone. Herein, we report the first case (to our knowledge o …
A particularly severe form, often accompanied by rhabdomyolysis, has been reported with the use of lovastatin and gemfibrozil; howeve …
Gemfibrozil-lovastatin-associated myalgia.
Rosenson RS. Rosenson RS. Am J Cardiol. 1993 Feb 15;71(5):497. doi: 10.1016/0002-9149(93)90481-q. Am J Cardiol. 1993. PMID: 8498994 No abstract available.
Inhibition of CYP2C8 by Acyl Glucuronides of Gemfibrozil and Clopidogrel: Pharmacological Significance, Progress and Challenges.
Shah MB. Shah MB. Biomolecules. 2022 Sep 1;12(9):1218. doi: 10.3390/biom12091218. Biomolecules. 2022. PMID: 36139056 Free PMC article. Review.
The lipid-regulating drug gemfibrozil is a useful medication for reducing high cholesterol and triglycerides in the blood. ...It is not clear how an acyl glucuronide metabolite of the drug gemfibrozil or clopidogrel interacts in the active site of CYP2C8 and selecti …
The lipid-regulating drug gemfibrozil is a useful medication for reducing high cholesterol and triglycerides in the blood. ...It is n …
Gemfibrozil in Combination with Statins-Is It Really Contraindicated?
Wiggins BS, Saseen JJ, Morris PB. Wiggins BS, et al. Curr Atheroscler Rep. 2016 Apr;18(4):18. doi: 10.1007/s11883-016-0571-8. Curr Atheroscler Rep. 2016. PMID: 26932225 Review.
Gemfibrozil is a lipid-modifying agent that belongs to the fibric acid derivative class. ...However, despite these concerns, there are situations in which the use of gemfibrozil in combination with a statin may be necessary. Understanding the metabolism of gemfib …
Gemfibrozil is a lipid-modifying agent that belongs to the fibric acid derivative class. ...However, despite these concerns, there ar …
Gemfibrozil-induced impotence.
Pizarro S, Bargay J, D'Agosto P. Pizarro S, et al. Lancet. 1990 Nov 3;336(8723):1135. doi: 10.1016/0140-6736(90)92618-r. Lancet. 1990. PMID: 1978015 No abstract available.
Gemfibrozil-induced impotence.
Figueras A, Castel JM, LaPorte JR, Capellà D. Figueras A, et al. Ann Pharmacother. 1993 Jul-Aug;27(7-8):982. doi: 10.1177/106002809302700737. Ann Pharmacother. 1993. PMID: 8364294 No abstract available.
Gemfibrozil-induced headache.
Alvarez-Sabin J, Codina A, Rodríguez C, Laporte JR. Alvarez-Sabin J, et al. Lancet. 1988 Nov 26;2(8622):1246. doi: 10.1016/s0140-6736(88)90830-6. Lancet. 1988. PMID: 2903970 No abstract available.
Gemfibrozil-induced impotence.
Bain SC, Lemon M, Jones AF. Bain SC, et al. Lancet. 1990 Dec 1;336(8727):1389. doi: 10.1016/0140-6736(90)92954-g. Lancet. 1990. PMID: 1978207 No abstract available.
2,305 results