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1,739 results

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Page 1
Netilmicin and gentamicin: comparative pharmacology in humans.
Riff LJ, Moreschi G. Riff LJ, et al. Antimicrob Agents Chemother. 1977 Apr;11(4):609-14. doi: 10.1128/AAC.11.4.609. Antimicrob Agents Chemother. 1977. PMID: 856012 Free PMC article. Clinical Trial.
Thirteen male subjects received 1 mg of either gentamicin or netilmicin per kg, first intramuscularly and then intravenously. After the intramuscular dose, concentrations of gentamicin in the serum were more variable than those of netilmicin. ...Serum clearance of n …
Thirteen male subjects received 1 mg of either gentamicin or netilmicin per kg, first intramuscularly and then intravenously. After t …
Comparative clinical studies of ototoxicity and nephrotoxicity of amikacin and gentamicin.
Lerner SA, Seligsohn R, Matz GJ. Lerner SA, et al. Am J Med. 1977 Jun;62(6):919-23. doi: 10.1016/0002-9343(77)90661-1. Am J Med. 1977. PMID: 868906 Clinical Trial.
A comparative study of the oto- and nephrotoxicity of amikacin and gentamicin was carried out prospectively. Twenty-six gentamicin-treated patients and 27 amikacin-treated patients were monitored for changes in auditory and renal function during and after therapy. . …
A comparative study of the oto- and nephrotoxicity of amikacin and gentamicin was carried out prospectively. Twenty-six gentamicin …
Ophthalmic fluorometholone-gentamicin versus ophthalmic betamethasone-gentamicin following cataract surgery.
Steinbach PD, Bauer J, Sunder Raj P. Steinbach PD, et al. Ocul Immunol Inflamm. 1997 Mar;5(1):51-4. doi: 10.3109/09273949709085050. Ocul Immunol Inflamm. 1997. PMID: 9145693 Clinical Trial.
A prospective, randomised, investigator-masked, parallel-group study was performed to compare fluorometholone-gentamicin eye drops and ointment with betamethasone-gentamicin eyedrops and ointment in the control of ocular inflammation after cataract surgery. ...Both …
A prospective, randomised, investigator-masked, parallel-group study was performed to compare fluorometholone-gentamicin eye drops an …
Assessment of the enzymuria resulting from gentamicin alone and combinations of gentamicin with various beta-lactam antibiotics.
Nix DE, Thomas JK, Symonds WT, Spivey JM, Wilton JH, Gagliardi NC, Schentag JJ. Nix DE, et al. Ann Pharmacother. 1997 Jun;31(6):696-703. doi: 10.1177/106002809703100605. Ann Pharmacother. 1997. PMID: 9184707 Clinical Trial.
Antimicrobial combinations studied included gentamicin plus placebo and gentamicin plus ticarcillin/clavulanate (protocol 1); and gentamicin plus placebo, gentamicin plus piperacillin, and gentamicin plus ceftazidime (protocol 2). ...RESULTS: Th …
Antimicrobial combinations studied included gentamicin plus placebo and gentamicin plus ticarcillin/clavulanate (protocol 1); …
Effect of topical gentamicin in preventing surgical site infection in elective incisional hernia repair in a randomized controlled trial.
Hidalgo NJ, Juvany M, Guillaumes S, Hoyuela C, Vidal Ó, Pera M. Hidalgo NJ, et al. Sci Rep. 2024 Nov 20;14(1):28755. doi: 10.1038/s41598-024-80112-y. Sci Rep. 2024. PMID: 39567596 Free PMC article. Clinical Trial.
The incidence of SSI and other surgical site complications was compared between both groups, and the presence of adverse effects with the use of topical gentamicin. Data from 146 patients were included for analysis: 74 in the gentamicin group and 72 in the saline so …
The incidence of SSI and other surgical site complications was compared between both groups, and the presence of adverse effects with the us …
A randomized comparison of the safety and efficacy of once-daily gentamicin or thrice-daily gentamicin in combination with ticarcillin-clavulanate.
Gilbert DN, Lee BL, Dworkin RJ, Leggett JL, Chambers HF, Modin G, Täuber MG, Sande MA. Gilbert DN, et al. Am J Med. 1998 Sep;105(3):182-91. doi: 10.1016/s0002-9343(98)00244-7. Am J Med. 1998. PMID: 9753020 Clinical Trial.
CONCLUSIONS: Gentamicin once a day plus TC, gentamicin three times a day plus TC, and TC alone had similar effects in seriously ill hospitalized patients. ...Using a nonvalidated post-hoc analysis, renal function was better preserved in gentamicin once-a-day …
CONCLUSIONS: Gentamicin once a day plus TC, gentamicin three times a day plus TC, and TC alone had similar effects in seriousl …
Double-blind comparison of the nephrotoxicity and auditory toxicity of gentamicin and tobramycin.
Smith CR, Lipsky JJ, Laskin OL, Hellmann DB, Mellits ED, Longstreth J, Lietman PS. Smith CR, et al. N Engl J Med. 1980 May 15;302(20):1106-9. doi: 10.1056/NEJM198005153022002. N Engl J Med. 1980. PMID: 6988713 Clinical Trial.
Auditory toxicity developed in five of 47 (10 per cent) given gentamicin and five of 44 (11 per cent) given tobramycin. Nephrotoxicity developed in 19 of 72 (26 per cent) given gentamicin and nine of 74 (12 per cent) given tobramycin (P less than 0.025). ...We concl …
Auditory toxicity developed in five of 47 (10 per cent) given gentamicin and five of 44 (11 per cent) given tobramycin. Nephrotoxicit …
Once-daily gentamicin versus once-daily netilmicin in patients with serious infections--a randomized clinical trial.
Prins JM, Büller HR, Kuijper EJ, Tange RA, Speelman P. Prins JM, et al. J Antimicrob Chemother. 1994 Apr;33(4):823-35. doi: 10.1093/jac/33.4.823. J Antimicrob Chemother. 1994. PMID: 8056701 Clinical Trial.
Median first serum trough and peak concentrations were 0.4/9.5 mg/L and 0.4/12.2 mg/L, for gentamicin and netilmicin respectively. A good clinical response was observed in 50/54 (92.6%) evaluable patients treated with gentamicin and in 48/52 (92.3%) netilmicin-treat …
Median first serum trough and peak concentrations were 0.4/9.5 mg/L and 0.4/12.2 mg/L, for gentamicin and netilmicin respectively. A …
Ototoxicity and nephrotoxicity of gentamicin vs netilmicin in patients with serious infections. A randomized clinical trial.
Tange RA, Dreschler WA, Prins JM, Büller HR, Kuijper EJ, Speelman P. Tange RA, et al. Clin Otolaryngol Allied Sci. 1995 Apr;20(2):118-23. doi: 10.1111/j.1365-2273.1995.tb00026.x. Clin Otolaryngol Allied Sci. 1995. PMID: 7634515 Clinical Trial.
A good clinical response was observed in 50 of the 54 evaluable patients (92.6%) treated with gentamicin and in 48/52 (92.3%) netilmicin treated patients. Nephrotoxicity developed in 5/72 (6.9%) gentamicin patients and in 10/69 (14.5%) treated with netilmicin. ...We …
A good clinical response was observed in 50 of the 54 evaluable patients (92.6%) treated with gentamicin and in 48/52 (92.3%) netilmi …
Comparative nephrotoxicity of gentamicin and tobramycin: pharmacokinetic and clinical studies in 201 patients.
Schentag JJ, Plaut ME, Cerra FB. Schentag JJ, et al. Antimicrob Agents Chemother. 1981 May;19(5):859-66. doi: 10.1128/AAC.19.5.859. Antimicrob Agents Chemother. 1981. PMID: 7294770 Free PMC article. Clinical Trial.
A total of 201 critically ill patients were studied during 267 courses of gentamicin or tobramycin treatment (139 gentamicin courses and 128 tobramycin courses). Of these 267 courses, pharmacokinetic and clinical data were obtained for 240 (120 gentamicin and …
A total of 201 critically ill patients were studied during 267 courses of gentamicin or tobramycin treatment (139 gentamicin c …
1,739 results