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Diabetische Nephropathie und Anpassung der antidiabetischen Therapie bei Niereninsuffizienz.
Winzeler B, Dickenmann M, Jehle AW. Winzeler B, et al. Ther Umsch. 2015 Mar;72(3):149-55. doi: 10.1024/0040-5930/a000658. Ther Umsch. 2015. PMID: 25722307 Review. German.

The risk for hypoglycemia is particularly high for the sulfonylureas glibenclamide and glimepiride and they are contraindicated once the GFR is < 60 ml/min/1.73 m2. Because of the increased risk of lactic acidosis, metformin requires a dose adjustment if the GFR is <

The risk for hypoglycemia is particularly high for the sulfonylureas glibenclamide and glimepiride and they are contraindicated once …
[Metformin-induced lactic acidosis].
Reeker W, Schneider G, Felgenhauer N, Tempel G, Kochs E. Reeker W, et al. Dtsch Med Wochenschr. 2000 Mar 3;125(9):249-51. doi: 10.1055/s-2007-1024085. Dtsch Med Wochenschr. 2000. PMID: 10742816 Review. German.
She was a diabetic being treated with metformin and glimepiride and was in incipient renal failure (serum creatinine 1.5 mg/dl). She was also in heart failure due to coronary heart disease and was in a debilitated state. ...
She was a diabetic being treated with metformin and glimepiride and was in incipient renal failure (serum creatinine 1.5 mg/dl). She …
Inhibition potential of glimepiride (gli) towards important UDP-glucuronosyltransferase (UGT) isoforms in human liver.
Fu JF, Ren QY, Zhang NY, Gao B, Tu YY, Fu GQ, Li DH, Zhang YS. Fu JF, et al. Pharmazie. 2012 Aug;67(8):715-7. Pharmazie. 2012. PMID: 22957438
The results showed that 100 microM of glimepiride inhibited UGT1A1, UGT1A3, UGT1A6, UGT1A9, UGT2B7 and UGT2B15 by 54.7%, 43.1%, 100%, 70.5%, 32.7 and 37.2%, respectively. Given that glimepiride exhibited strong inhibition towards UGT1A6, further inhibitory kinetic b …
The results showed that 100 microM of glimepiride inhibited UGT1A1, UGT1A3, UGT1A6, UGT1A9, UGT2B7 and UGT2B15 by 54.7%, 43.1%, 100%, …
Fast HPLC method for the determination of glimepiride, glibenclamide, and related substances using monolithic column and flow program.
El Deeb S, Schepers U, Wätzig H. El Deeb S, et al. J Sep Sci. 2006 Jul;29(11):1571-7. doi: 10.1002/jssc.200600056. J Sep Sci. 2006. PMID: 16922272
This work presents a fast method for the simultaneous separation and determination of glimepiride, glibenclamide, and two related substances by RP LC. The separation was performed on a Chromolith Performance (RP-18e, 100 mm x 4.6 mm) column. ...
This work presents a fast method for the simultaneous separation and determination of glimepiride, glibenclamide, and two related sub …
Presentation of glomerulocystic disease in a young onset diabetes: A case report.
Huang WH, Tu KH, Chen TD, Weng CH, Hsu CW. Huang WH, et al. Medicine (Baltimore). 2024 Jan 26;103(4):e36952. doi: 10.1097/MD.0000000000036952. Medicine (Baltimore). 2024. PMID: 38277556 Free PMC article.
DIAGNOSIS: A treatment plan was initiated to stabilize creatinine levels, including medications such as Glimepiride, Glyxambi, Bisoprolol, Amlodipine, and Valsartan. However, despite diligent medication management, proteinuria persisted, prompting further evaluation. ...
DIAGNOSIS: A treatment plan was initiated to stabilize creatinine levels, including medications such as Glimepiride, Glyxambi, Bisopr …
Development and application of an analytical method for curdione quantification in pregnant Sprague-Dawley rats by LC-MS/MS.
Meng X, Zhang T, Li Y, Pan Q, Jiang J, Luo Y, Chong L, Yang Y, Xu S, Zhou L, Sun Z. Meng X, et al. Biomed Chromatogr. 2015 Oct;29(10):1499-505. doi: 10.1002/bmc.3449. Epub 2015 Mar 4. Biomed Chromatogr. 2015. PMID: 25736727
A sensitive analytical method for determining the plasma concentration of curdione was developed and applied in the determination of curdione in pregnant Sprague-Dawley rats as a simulated model. Glimepiride was used as an internal standard and chromatographic separation w …
A sensitive analytical method for determining the plasma concentration of curdione was developed and applied in the determination of curdion …
Liraglutide, a once-daily human GLP-1 analogue, added to a sulphonylurea over 26 weeks produces greater improvements in glycaemic and weight control compared with adding rosiglitazone or placebo in subjects with Type 2 diabetes (LEAD-1 SU).
Marre M, Shaw J, Brändle M, Bebakar WM, Kamaruddin NA, Strand J, Zdravkovic M, Le Thi TD, Colagiuri S; LEAD-1 SU study group. Marre M, et al. Diabet Med. 2009 Mar;26(3):268-78. doi: 10.1111/j.1464-5491.2009.02666.x. Diabet Med. 2009. PMID: 19317822 Free PMC article. Clinical Trial.
AIM: To compare the effects of combining liraglutide (0.6, 1.2 or 1.8 mg/day) or rosiglitazone 4 mg/day (all n >or= 228) or placebo (n = 114) with glimepiride (2-4 mg/day) on glycaemic control, body weight and safety in Type 2 diabetes. ...Main adverse events for all tr …
AIM: To compare the effects of combining liraglutide (0.6, 1.2 or 1.8 mg/day) or rosiglitazone 4 mg/day (all n >or= 228) or placebo (n = …
[Differential type 2 diabetes therapy based on pathophysiological aspects].
Hanefeld M, Fischer S. Hanefeld M, et al. Ther Umsch. 2002 Aug;59(8):393-401. doi: 10.1024/0040-5930.59.8.393. Ther Umsch. 2002. PMID: 12235731 German.
Patients with IFH profit particularly from metformin and long acting sulfonylureas (glimepiride, glibenclamide). Patients with IPH are candidates for prandial antidiabetics (AGI, nateglinide, repaglinide). ...
Patients with IFH profit particularly from metformin and long acting sulfonylureas (glimepiride, glibenclamide). Patients with IPH ar …