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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1968 1
1969 18
1970 47
1971 65
1972 58
1973 70
1974 67
1975 62
1976 51
1977 45
1978 33
1979 35
1980 42
1981 33
1982 39
1983 55
1984 77
1985 73
1986 74
1987 66
1988 86
1989 98
1990 156
1991 216
1992 295
1993 334
1994 345
1995 306
1996 334
1997 405
1998 387
1999 391
2000 368
2001 344
2002 369
2003 345
2004 397
2005 351
2006 410
2007 384
2008 317
2009 343
2010 375
2011 431
2012 404
2013 345
2014 379
2015 372
2016 302
2017 322
2018 313
2019 317
2020 330
2021 288
2022 265
2023 233
2024 107

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11,860 results

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Page 1
Glibenclamide as a neuroprotective antidementia drug.
Zubov A, Muruzheva Z, Tikhomirova M, Karpenko M. Zubov A, et al. Arch Physiol Biochem. 2022 Dec;128(6):1693-1696. doi: 10.1080/13813455.2020.1789170. Epub 2020 Jul 11. Arch Physiol Biochem. 2022. PMID: 32654523 Review.
We are aiming here to review available data on the most widely used hypoglycaemic drug, glibenclamide and find possible relationship of its targets to the pathogenesis of cognitive impairment....
We are aiming here to review available data on the most widely used hypoglycaemic drug, glibenclamide and find possible relationship …
Is glyburide safe in pregnancy?
Kimber-Trojnar Ż, Marciniak B, Patro-Malysza J, Skorzynska-Dziduszko K, Poniedzialek-Czajkowska E, Mierzynski R, Galczynski K, Trojnar M, Leszczynska-Gorzelak B, Oleszczuk J. Kimber-Trojnar Ż, et al. Curr Pharm Biotechnol. 2014;15(1):100-12. doi: 10.2174/1389201015666140330200254. Curr Pharm Biotechnol. 2014. PMID: 24720590 Review.
It is therefore highly desirable to find an effective alternative to insulin. Glyburide (also known as glibenclamide) is currently classified as Category C by the U.S. ...Since the contradictory data primarily concern the transfer of glyburide across the plac …
It is therefore highly desirable to find an effective alternative to insulin. Glyburide (also known as glibenclamide) is curre …
Structural basis of bile salt extrusion and small-molecule inhibition in human BSEP.
Liu H, Irobalieva RN, Kowal J, Ni D, Nosol K, Bang-Sørensen R, Lancien L, Stahlberg H, Stieger B, Locher KP. Liu H, et al. Nat Commun. 2023 Nov 10;14(1):7296. doi: 10.1038/s41467-023-43109-1. Nat Commun. 2023. PMID: 37949847 Free PMC article.
BSEP dysfunction, caused by mutations or induced by drugs, is frequently associated with severe cholestatic liver disease. We report the cryo-EM structure of glibenclamide-bound human BSEP in nanodiscs, revealing the basis of small-molecule inhibition. Glibenclamide
BSEP dysfunction, caused by mutations or induced by drugs, is frequently associated with severe cholestatic liver disease. We report the cry …
Glibenclamide-induced cholestasis.
Del-Val A, Garrigues V, Ponce J, Benages R. Del-Val A, et al. J Hepatol. 1991 Nov;13(3):375. doi: 10.1016/0168-8278(91)90085-p. J Hepatol. 1991. PMID: 1808229 No abstract available.
Targeting of neuroinflammation by glibenclamide in Covid-19: old weapon from arsenal.
Batiha GE, Al-Kuraishy HM, Al-Gareeb AI, Alruwaili M, AlRuwaili R, Albogami SM, Alorabi M, Saad HM, Simal-Gandara J. Batiha GE, et al. Inflammopharmacology. 2023 Feb;31(1):1-7. doi: 10.1007/s10787-022-01087-8. Epub 2022 Nov 23. Inflammopharmacology. 2023. PMID: 36418600 Free PMC article. Review.
Glibenclamide reduces neuroinflammation and associated BBB injury by inhibiting the nod-like receptor pyrin 3 (NLRP3) inflammasome, oxidative stress, and microglial activation. Therefore, glibenclamide through inhibition of NLRP3 inflammasome, microglial activation,
Glibenclamide reduces neuroinflammation and associated BBB injury by inhibiting the nod-like receptor pyrin 3 (NLRP3) inflammasome, o
Neuroprotection of NSC Therapy is Superior to Glibenclamide in Cardiac Arrest-Induced Brain Injury via Neuroinflammation Regulation.
Wang Z, Zhang S, Du J, Lachance BB, Chen S, Polster BM, Jia X. Wang Z, et al. Transl Stroke Res. 2023 Oct;14(5):723-739. doi: 10.1007/s12975-022-01047-y. Epub 2022 Aug 3. Transl Stroke Res. 2023. PMID: 35921049
Neuroinflammation has been a target for two promising but underdeveloped post-CA therapies: neural stem cell (NSC) engrafting and glibenclamide (GBC). It is critical to understand whether one therapy has superior efficacy over the other and to further understand their immu …
Neuroinflammation has been a target for two promising but underdeveloped post-CA therapies: neural stem cell (NSC) engrafting and glibenc
Mechanism of Action of Novel Glibenclamide Derivatives on Potassium and Calcium Channels for Insulin Secretion.
Frederico MJS, Castro AJG, Menegaz D, Murat CB, Mendes CP, Mascarello A, Nunes RJ, Silva FRMB. Frederico MJS, et al. Curr Drug Targets. 2017;18(6):641-650. doi: 10.2174/1389450117666160615084752. Curr Drug Targets. 2017. PMID: 27316908 Review.
Glibenclamide is widely used and remains a cornerstone and an effective antihyperglycemic drug. ...Furthermore, the role of glibenclamide-based novel structures that promise less excitability of beta-cell in a long-term treatment with effectiveness and safety for di
Glibenclamide is widely used and remains a cornerstone and an effective antihyperglycemic drug. ...Furthermore, the role of gliben
[Glibenclamide as a promising agent for prevention and treatment of cerebral edema].
Tsarenko SV, Dzyadz'ko AM, Rybalko SS. Tsarenko SV, et al. Zh Vopr Neirokhir Im N N Burdenko. 2017;81(3):88-93. doi: 10.17116/neiro201781388-93. Zh Vopr Neirokhir Im N N Burdenko. 2017. PMID: 28665392 Free article. Review. Russian.
The article presents a review of the literature on the use of a fundamentally new technique for prevention and treatment of cerebral edema. A drug glibenclamide, which is used to treat type 2 diabetes mellitus, is able to reduce cerebral edema and neuronal damage as eviden …
The article presents a review of the literature on the use of a fundamentally new technique for prevention and treatment of cerebral edema. …
Management of sulfonylurea-treated monogenic diabetes in pregnancy: implications of placental glibenclamide transfer.
Shepherd M, Brook AJ, Chakera AJ, Hattersley AT. Shepherd M, et al. Diabet Med. 2017 Oct;34(10):1332-1339. doi: 10.1111/dme.13388. Epub 2017 Jun 13. Diabet Med. 2017. PMID: 28556992 Free PMC article. Review.
The optimum treatment for HNF1A/HNF4A maturity-onset diabetes of the young and ATP-sensitive potassium (K(ATP) ) channel neonatal diabetes, outside pregnancy, is sulfonylureas, but there is little evidence regarding the most appropriate treatment during pregnancy. Glibenclamid
The optimum treatment for HNF1A/HNF4A maturity-onset diabetes of the young and ATP-sensitive potassium (K(ATP) ) channel neonatal diabetes, …
11,860 results
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