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Year Number of Results
2001 1
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278 results

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Page 1
Drugs for hypertension.
[No authors listed] [No authors listed] Med Lett Drugs Ther. 2024 May 27;66(1703):81-88. doi: 10.58347/tml.2024.1703a. Med Lett Drugs Ther. 2024. PMID: 38771738 Review. No abstract available.
Effects of Sacubitril/Valsartan Versus Olmesartan on Central Hemodynamics in the Elderly With Systolic Hypertension: The PARAMETER Study.
Williams B, Cockcroft JR, Kario K, Zappe DH, Brunel PC, Wang Q, Guo W. Williams B, et al. Hypertension. 2017 Mar;69(3):411-420. doi: 10.1161/HYPERTENSIONAHA.116.08556. Epub 2017 Jan 16. Hypertension. 2017. PMID: 28093466 Clinical Trial.
The study extended double-blind treatment for 12 to 52 weeks, during which amlodipine (2.5-5 mg) and subsequently hydrochlorothiazide (6.25-25 mg) were added-on for patients not achieving blood pressure target (<140/90). ...After 52 weeks, blood pressure parameters were …
The study extended double-blind treatment for 12 to 52 weeks, during which amlodipine (2.5-5 mg) and subsequently hydrochlorothiazide
Efficacy and safety of olmesartan medoxomil alone and in combination with hydrochlorothiazide.
Punzi HA. Punzi HA. Expert Rev Cardiovasc Ther. 2009 Mar;7(3):229-39. doi: 10.1586/14779072.7.3.229. Expert Rev Cardiovasc Ther. 2009. PMID: 19296759 Review.
In a series of clinical trials, the combination of olmesartan medoxomil, a well-established angiotensin receptor blocker, and hydrochlorothiazide, a thiazide diuretic, has produced greater reductions in systolic BP and diastolic BP and greater proportions of patient …
In a series of clinical trials, the combination of olmesartan medoxomil, a well-established angiotensin receptor blocker, and hydr
Exploring the Effectiveness and Safety of Azilsartan-Medoxomil/Chlorthalidone Versus Olmesartan-Medoxomil/Hydrochlorothiazide in Hypertensive Patients: A Meta-Analysis.
Kumar L, Khuwaja S, Kumar A, Memon UA, Kumar M, Ashok A, Lohana M, Qudoos A, Kashif M, Khatri M, Kumar S, Sapna F, Dass A, Varrassi G. Kumar L, et al. Cureus. 2023 Jun 30;15(6):e41198. doi: 10.7759/cureus.41198. eCollection 2023 Jun. Cureus. 2023. PMID: 37525792 Free PMC article. Review.
This study aims to assess the effectiveness and safety of azilsartan-medoxomil/chlorthalidone (AZI-M/CT) compared to olmesartan-medoxomil/hydrochlorothiazide (OLM/HCTZ) in patients with hypertension. Systematic searches were conducted on PubMed, Google Scholar, and …
This study aims to assess the effectiveness and safety of azilsartan-medoxomil/chlorthalidone (AZI-M/CT) compared to olmesartan-medox …
Pharmacokinetic properties and bioequivalence of olmesartan medoxomil/hydrochlorothiazide in healthy Korean male subjects.
Jin C, Jeon JY, Im YJ, Jung JA, Kim Y, Park K, Choi Y, Chae SW, Kim MG. Jin C, et al. Int J Clin Pharmacol Ther. 2014 Jan;52(1):64-72. doi: 10.5414/CP201991. Int J Clin Pharmacol Ther. 2014. PMID: 24290413 Clinical Trial.
Olmesartan medoxomil inhibits the vasoconstrictor effects of angiotensin II. Hydrochlorothiazide (HCTZ) promotes sodium excretion, resulting in a reduction of plasma volume and peripheral resistance. ...OBJECTIVE: To assess bioequivalence between fixed-dose combinat
Olmesartan medoxomil inhibits the vasoconstrictor effects of angiotensin II. Hydrochlorothiazide (HCTZ) promotes sodium excret
Drug-induced hyponatraemia and possible related signals: Analysis of 659 cases reported to the Spanish Pharmacovigilance System and disproportionality analysis.
Estévez Asensio L, García M, Verde Rello Z, Velasco-González V, Fernández-Araque AM, Sainz-Gil M. Estévez Asensio L, et al. Med Clin (Barc). 2024 Dec 27;163(12):600-608. doi: 10.1016/j.medcli.2024.07.021. Epub 2024 Oct 16. Med Clin (Barc). 2024. PMID: 39419657 Free article. English, Spanish.
Regarding new safety signals, the Reporting Odds Ratio (ROR) (95% CI) was found to be statistically significant for valsartan [7.7 (5.1-11.5)], olmesartan [7.3 (4.7-11.1)], amlodipine [3.4 (2.1-5.4)], pregabalin [2.5 (1.4-4.5)], irbesartan [18.6 (9.6-35.9)], paliperidone [ …
Regarding new safety signals, the Reporting Odds Ratio (ROR) (95% CI) was found to be statistically significant for valsartan [7.7 (5.1-11.5 …
Olmesartan medoxomil, amlodipine besylate and hydrochlorothiazide triple combination for hypertension.
Ram CV. Ram CV. Expert Rev Cardiovasc Ther. 2011 Jan;9(1):9-19. doi: 10.1586/erc.10.163. Expert Rev Cardiovasc Ther. 2011. PMID: 21166525 Review.
Recent data suggest that the combination of olmesartan medoxomil, amlodipine and hydrochlorothiazide is a rational treatment option offering safe and effective BP reductions and goal attainment in a greater proportion of patients compared with dual-combination regim …
Recent data suggest that the combination of olmesartan medoxomil, amlodipine and hydrochlorothiazide is a rational treatment o …
Clinical efficacy and safety of olmesartan/hydrochlorothiazide combination therapy in patients with essential hypertension.
Ruilope LM. Ruilope LM. Vasc Health Risk Manag. 2008;4(6):1237-48. doi: 10.2147/vhrm.s3642. Vasc Health Risk Manag. 2008. PMID: 19337537 Free PMC article. Review.
The results presented here demonstrate that olmesartan is effective when added to HCTZ monotherapy or when HCTZ is added to olmesartan monotherapy, both over the short and long term. Moderate to severe hypertension responds well to olmesartan/HCTZ combination …
The results presented here demonstrate that olmesartan is effective when added to HCTZ monotherapy or when HCTZ is added to olmesa
Impact of Sex and Genetic Variation in Relevant Pharmacogenes on the Pharmacokinetics and Safety of Valsartan, Olmesartan and Hydrochlorothiazide.
Soria-Chacartegui P, Zubiaur P, Ochoa D, Navares-Gómez M, Abbes H, Villapalos-García G, de Miguel A, González-Iglesias E, Rodríguez-Lopez A, Mejía-Abril G, Martín-Vilchez S, Luquero-Bueno S, Román M, Abad-Santos F. Soria-Chacartegui P, et al. Int J Mol Sci. 2023 Oct 17;24(20):15265. doi: 10.3390/ijms242015265. Int J Mol Sci. 2023. PMID: 37894954 Free PMC article.
The study population were 64 volunteers from seven bioequivalence trials investigating formulations with valsartan, olmesartan and/or hydrochlorothiazide. Every volunteer was genotyped for 10 genetic variants in different transporters' genes. ...Sex impacted valsart …
The study population were 64 volunteers from seven bioequivalence trials investigating formulations with valsartan, olmesartan and/or …
Interaction and Compatibility Studies in the Development of Olmesartan Medoxomil and Hydrochlorothiazide Formulations under a Real Manufacturing Process.
Murillo-Fernández MA, Montero-Zeledón E, Abdala-Saiz A, Vega-Baudrit JR, Araya-Sibaja AM. Murillo-Fernández MA, et al. Pharmaceutics. 2022 Feb 16;14(2):424. doi: 10.3390/pharmaceutics14020424. Pharmaceutics. 2022. PMID: 35214156 Free PMC article.
A drug-drug and drug-excipient interactions and compatibilities study was conducted for two fixed-dose combination (FDC) products containing olmesartan medoxomil (OLM)/hydrochlorothiazide (HCT) 20/12.5 mg and OLM/HCT 40/12.5 mg during their development including sto …
A drug-drug and drug-excipient interactions and compatibilities study was conducted for two fixed-dose combination (FDC) products containing …
278 results