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Year Number of Results
1999 3
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2003 5
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2006 5
2007 2
2008 6
2009 6
2010 5
2011 1
2012 3
2013 5
2014 5
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2019 3
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75 results

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Page 1
Telmisartan and hydrochlorothiazide antihypertensive treatment in high sodium intake population: a randomized double-blind trial.
Zhang P, Wang H, Sun L, Zhang J, Xi Y, Wu Y, Yan LL, Li X, Sun N. Zhang P, et al. J Hypertens. 2017 Oct;35(10):2077-2085. doi: 10.1097/HJH.0000000000001407. J Hypertens. 2017. PMID: 28509725 Clinical Trial.
OBJECTIVES: To compare the blood pressure (BP)-lowering effects of telmisartan 40 mg/day and hydrochlorothiazide (HCTZ) 25 mg/day in high sodium intake patients with mild-to-moderate hypertension in China. ...Telmisartan showed better DBP-lowering effect and …
OBJECTIVES: To compare the blood pressure (BP)-lowering effects of telmisartan 40 mg/day and hydrochlorothiazide (HCTZ) 25 mg/ …
Bioequivalence and Food Effect Assessment of Two Fixed-Dose Combination Formulations of Telmisartan-Hydrochlorothiazide Tablets in Chinese Healthy Subjects.
Hu M, Yang M, Zhang S, Li J, Pang H, Pei Y, Guo C, Wang X. Hu M, et al. Clin Transl Sci. 2025 May;18(5):e70228. doi: 10.1111/cts.70228. Clin Transl Sci. 2025. PMID: 40279189 Free PMC article. Clinical Trial.
This study assessed the bioequivalence and food effect of two fixed-dose combination (FDC) formulations of telmisartan-hydrochlorothiazide tablets (telmisartan 40 mg, hydrochlorothiazide 12.5 mg) in healthy Chinese subjects. ...The pharmacokinetic char …
This study assessed the bioequivalence and food effect of two fixed-dose combination (FDC) formulations of telmisartan-hydrochloro …
Combination treatment with telmisartan and hydrochlorothiazide in black patients with mild to moderate hypertension.
McGill JB, Reilly PA. McGill JB, et al. Clin Cardiol. 2001 Jan;24(1):66-72. doi: 10.1002/clc.4960240111. Clin Cardiol. 2001. PMID: 11195609 Free PMC article. Clinical Trial.

These reductions represented benefits of 13.7/8.7 mmHg over telmisartan 80 mg and 12.3/8.1 mmHg over HCTZ 12.5 mg (p < 0.01). Telmisartan 40 mg/HCTZ 12.5 mg reduced supine trough SBP/DBP by 14.3/10.0 mmHg, amounting to 12.3/3.3 mmHg more than telmisartan 4

…

These reductions represented benefits of 13.7/8.7 mmHg over telmisartan 80 mg and 12.3/8.1 mmHg over HCTZ 12.5 mg (p < 0.01). T

…
Comparison of telmisartan/amlodipine and telmisartan/hydrochlorothiazide in the treatment of Japanese patients with uncontrolled hypertension: the TAT-Kobe study.
Kondo K, Toh R, Ishida T, Mori K, Yasuda T, Hirata K. Kondo K, et al. Blood Press Monit. 2016 Jun;21(3):171-7. doi: 10.1097/MBP.0000000000000172. Blood Press Monit. 2016. PMID: 26719915 Clinical Trial.
OBJECTIVE: The aim of this study was to compare the efficacy and safety of telmisartan plus amlodipine with telmisartan plus hydrochlorothiazide for the treatment of uncontrolled hypertension. ...Treatment with telmisartan/hydrochlorothiazide re …
OBJECTIVE: The aim of this study was to compare the efficacy and safety of telmisartan plus amlodipine with telmisartan plus …
Pharmacokinetic Interaction Among Telmisartan, Amlodipine, and Hydrochlorothiazide After a Single Oral Administration in Healthy Male Subjects.
Moon SJ, Jeon JY, Yu KS, Kim MG. Moon SJ, et al. Clin Ther. 2019 Nov;41(11):2273-2282. doi: 10.1016/j.clinthera.2019.08.020. Epub 2019 Sep 26. Clin Ther. 2019. PMID: 31564513 Clinical Trial.
The objective of this study was to evaluate the pharmacokinetic interaction among telmisartan, amlodipine, and hydrochlorothiazide. METHODS: A randomized, open-label, 3-period, 6-sequence, 3-treatment, single-dose crossover study was conducted in healthy male subjec …
The objective of this study was to evaluate the pharmacokinetic interaction among telmisartan, amlodipine, and hydrochlorothiazide …
Efficacy and tolerability of initial therapy with single-pill combination telmisartan/hydrochlorothiazide 80/25 mg in patients with grade 2 or 3 hypertension: a multinational, randomized, double-blind, active-controlled trial.
Zhu DL, Bays H, Gao P, Mattheus M, Voelker B, Ruilope LM. Zhu DL, et al. Clin Ther. 2012 Jul;34(7):1613-24. doi: 10.1016/j.clinthera.2012.05.007. Epub 2012 Jun 19. Clin Ther. 2012. PMID: 22717420 Clinical Trial.
OBJECTIVES: This study compared the effectiveness and tolerability of a single-pill combination (SPC) of telmisartan/hydrochlorothiazide 80/25 mg (T80/H25) with T80 monotherapy. METHODS: In a Phase IV, multinational, randomized, double-blind, double-dummy, active-co …
OBJECTIVES: This study compared the effectiveness and tolerability of a single-pill combination (SPC) of telmisartan/hydrochloroth …
Multiple-dose pharmacokinetics of telmisartan and of hydrochlorothiazide following concurrent administration in healthy subjects.
Young CL, Dias VC, Stangier J. Young CL, et al. J Clin Pharmacol. 2000 Dec;40(12 Pt 1):1323-30. J Clin Pharmacol. 2000. PMID: 11185630 Clinical Trial.
This open-label, crossover study had two objectives: to compare the steady-state pharmacokinetics of high-dose telmisartan with and without coadministered high-dose hydrochlorothiazide and to compare the steady-state pharmacokinetics of hydrochlorothiazide wi …
This open-label, crossover study had two objectives: to compare the steady-state pharmacokinetics of high-dose telmisartan with and w …
Efficacy and tolerability of a single-pill combination of telmisartan/hydrochlorothiazide 80/25 mg in Chinese and Korean patients with moderate to severe hypertension: a subgroup analysis of a randomized, double-blind, active-controlled trial.
Zhu DL, Gao PJ, Liu SW, Jeong MH, Mattheus M, Birgit V. Zhu DL, et al. Chin Med J (Engl). 2013 Nov;126(21):4072-7. Chin Med J (Engl). 2013. PMID: 24229676 Clinical Trial.
This randomized controlled trial subgroup analysis compared telmisartan 80 mg (T80)/hydrochlorothiazide 25 mg (H25) singlepill combination with T80 monotherapy, specifically in Chinese and Korean patients. METHODS: Patients with grade 2/3 hypertension were randomize …
This randomized controlled trial subgroup analysis compared telmisartan 80 mg (T80)/hydrochlorothiazide 25 mg (H25) singlepill …
Long-term efficacy and tolerability of telmisartan as monotherapy and in combination with other antihypertensive medications.
Neutel JM, Klein C, Meinicke TW, Schumacher H. Neutel JM, et al. Blood Press. 2002;11(5):302-9. doi: 10.1080/080370502320779511. Blood Press. 2002. PMID: 12458653 Free article. Clinical Trial.
This open-label, multicenter, extension study assessed the efficacy and tolerability of telmisartan 80 mg administered alone or with HCTZ and/or other antihypertensive agents over a maximal 1-year treatment period. ...At the final visit, DBP control was achieved in 70.0% ( …
This open-label, multicenter, extension study assessed the efficacy and tolerability of telmisartan 80 mg administered alone or with …
Fixed-dose Combination of Metoprolol, Telmisartan, and Chlorthalidone for Essential Hypertension in Adults with Stable Coronary Artery Disease: Phase III Study.
Sarkar G, Gaikwad VB, Sharma A, Halder SK, Kumar DA, Anand J, Agrawal S, Kumbhar A, Kinholkar B, Mathur R, Doshi M, Bachani D, Mehta S. Sarkar G, et al. Adv Ther. 2022 Feb;39(2):923-942. doi: 10.1007/s12325-021-01971-9. Epub 2021 Dec 17. Adv Ther. 2022. PMID: 34918194 Clinical Trial.
METHODS: In this phase III, open-label, multicenter study, 254 adults with stable CAD having uncontrolled hypertension despite being treated with FDC of metoprolol (25/50 mg) and telmisartan (40 mg) were included. Patients received either of the following FDC for 24 weeks: …
METHODS: In this phase III, open-label, multicenter study, 254 adults with stable CAD having uncontrolled hypertension despite being treated …
75 results