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Year Number of Results
1966 1
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1968 2
1970 3
1973 1
1974 1
1977 6
1978 6
1979 2
1980 3
1981 5
1982 4
1983 3
1984 7
1985 6
1986 12
1987 5
1988 3
1989 8
1990 8
1991 9
1992 4
1993 2
1994 3
1996 4
1997 2
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122 results

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Page 1
Effects of Triamterene in Hospitalized Patients with Heart Failure and Diuretic Resistance: A Randomized Clinical Trial.
Taban-Sadeghi M, Khani E, Khezripour K, Enamzadeh E, Safaei N, Entezari-Maleki T. Taban-Sadeghi M, et al. J Clin Pharmacol. 2023 Dec;63(12):1352-1358. doi: 10.1002/jcph.2321. Epub 2023 Aug 10. J Clin Pharmacol. 2023. PMID: 37493211 Clinical Trial.
Due to the potential benefits of triamterene in diuretic resistance, this study was performed to assess whether triamterene add-on to the standard treatment of heart failure (HF)-related diuretic resistance improves outcomes. ...Patients were randomized to receive e …
Due to the potential benefits of triamterene in diuretic resistance, this study was performed to assess whether triamterene ad …
Clinical experience with a new combination formulation of triamterene and hydrochlorothiazide (Maxzide) in patients with mild to moderate hypertension.
Williams RL, Clark T, Blume CD. Williams RL, et al. Am J Med. 1984 Nov 5;77(5A):62-6. doi: 10.1016/s0002-9343(84)80010-8. Am J Med. 1984. PMID: 6388328 Clinical Trial.
The results of an investigation to assess the clinical responses of patients with mild to moderate hypertension to a new combination formulation containing 75 mg triamterene and 50 mg hydrochlorothiazide are reported. One hundred fifty-six subjects entered the inves …
The results of an investigation to assess the clinical responses of patients with mild to moderate hypertension to a new combination formula …
Effects of triamterene and amiloride on urinary sediment in hypertensive patients taking hydrochlorothiazide.
Spence JD, Wong DG, Lindsay RM. Spence JD, et al. Lancet. 1985 Jul 13;2(8446):73-5. doi: 10.1016/s0140-6736(85)90180-1. Lancet. 1985. PMID: 2861527 Clinical Trial.
In a crossover study of 26 hypertensive patients, the effects of triamterene (50 mg/day) and amiloride (5 mg/day) on urinary sediment were compared. Each drug was given for one month and all patients also received hydrochlorothiazide (50 mg/day). ...In a clinic popu …
In a crossover study of 26 hypertensive patients, the effects of triamterene (50 mg/day) and amiloride (5 mg/day) on urinary sediment …
Double-blind comparison of triamterene plus hydrochlorothiazide and spironolactone plus hydrochlorothiazide in the treatment of hypertension.
Cocke TB, Fisch S, Gilmore HR, Okun R, Tamagna IG, Wipplinger K. Cocke TB, et al. J Clin Pharmacol. 1977 May-Jun;17(5-6):334-8. doi: 10.1002/j.1552-4604.1977.tb04613.x. J Clin Pharmacol. 1977. PMID: 323298 Clinical Trial.
The results from this double-blind, multi-investigator study showed that a combination of 50 mg triamterene plus 25 mg hydrochlorothiazide and a combination of 25 mg spironolactone plus 25 mg hydrochlorothiazide were equally efficacious in lowering blood pres …
The results from this double-blind, multi-investigator study showed that a combination of 50 mg triamterene plus 25 mg hydrochloro …
Bioequivalence study of a new tablet formulation of triamterene and hydrochlorothiazide.
Blume CD, Williams RL, Upton RA, Lin ET, Benet LZ. Blume CD, et al. Am J Med. 1984 Nov 5;77(5A):59-61. doi: 10.1016/s0002-9343(84)80009-1. Am J Med. 1984. PMID: 6496560 Clinical Trial.
A three-treatment, single-dose, crossover bioequivalence study was conducted in healthy volunteers to compare urinary drug recovery following administration of hydrochlorothiazide tablets, the currently marketed capsule formulation of triamterene and hydrochlorot …
A three-treatment, single-dose, crossover bioequivalence study was conducted in healthy volunteers to compare urinary drug recovery followin …
Pharmacokinetics and pharmacodynamics of triamterene and hydrochlorothiazide and their combination in healthy volunteers.
Möhrke W, Knauf H, Mutschler E. Möhrke W, et al. Int J Clin Pharmacol Ther. 1997 Oct;35(10):447-52. Int J Clin Pharmacol Ther. 1997. PMID: 9352394 Clinical Trial.
Moreover, although triamterene is mostly applied concomitantly with thiazide-type diuretics the interaction of triamterene (TA) with hydrochlorothiazide (HCT) is subject to a controversial discussion. Therefore, the aim of this study was to examine the dose l …
Moreover, although triamterene is mostly applied concomitantly with thiazide-type diuretics the interaction of triamterene (TA …
Absorption and disposition of a new low-dose combination formulation of hydrochlorothiazide and triamterene.
Williams RL, Lin ET, Liang-Gee W, Blume CD, Benet LZ. Williams RL, et al. Biopharm Drug Dispos. 1990 Apr;11(3):233-43. doi: 10.1002/bdd.2510110308. Biopharm Drug Dispos. 1990. PMID: 2328310 Clinical Trial.
Two studies are reported that assess the bioequivalence of a new half-strength drug combination containing 25 mg hydrochlorothiazide and 37.5 mg triamterene compared to a full-strength formulation containing 50 mg hydrochlorothiazide and 75 mg triamterene …
Two studies are reported that assess the bioequivalence of a new half-strength drug combination containing 25 mg hydrochlorothiazide …
Blood pressure lowering and potassium conservation by triamterene-hydrochlorothiazide and amiloride-hydrochlorothiazide in hypertension.
Maxwell MH, Brachfeld J, Itskovitz H, Lunn JA, Moser M, Zawada ET. Maxwell MH, et al. Clin Pharmacol Ther. 1985 Jan;37(1):61-5. doi: 10.1038/clpt.1985.12. Clin Pharmacol Ther. 1985. PMID: 3880686 Clinical Trial.
Five subjects receiving amiloride-hydrochlorothiazide (12%) and two subjects receiving triamterene-hydrochlorothiazide (5%) had hypokalemia (serum potassium level less than 3.5 mEq/l) at week 9. ...Weight loss was greater in the amiloride-hydrochlorothiazi …
Five subjects receiving amiloride-hydrochlorothiazide (12%) and two subjects receiving triamterene-hydrochlorothiazide …
Comparative efficacy and bioequivalence of a brand-name and a generic triamterene-hydrochlorothiazide combination product.
Sharoky M, Perkal M, Tabatznik B, Cane RC Jr, Costello K, Goodwin P. Sharoky M, et al. Clin Pharm. 1989 Jul;8(7):496-500. Clin Pharm. 1989. PMID: 2752698 Clinical Trial.
The clinical efficacy, safety, and bioavailability of a generic triamterene-hydrochlorothiazide product were compared with those of Dyazide. Thirty patients who had a diagnosis of nonlabile essential hypertension and who were receiving Dyazide (triamterene 50 …
The clinical efficacy, safety, and bioavailability of a generic triamterene-hydrochlorothiazide product were compared with tho …
122 results