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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1965 9
1966 6
1967 15
1968 30
1969 32
1970 40
1971 36
1972 36
1973 37
1974 41
1975 48
1976 61
1977 40
1978 60
1979 46
1980 51
1981 49
1982 58
1983 57
1984 79
1985 92
1986 90
1987 85
1988 113
1989 113
1990 115
1991 115
1992 114
1993 140
1994 207
1995 203
1996 208
1997 235
1998 242
1999 229
2000 237
2001 224
2002 261
2003 235
2004 321
2005 318
2006 316
2007 301
2008 264
2009 252
2010 275
2011 310
2012 299
2013 313
2014 333
2015 302
2016 257
2017 225
2018 195
2019 186
2020 187
2021 158
2022 154
2023 128
2024 71

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8,407 results

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Page 1
Modified-Release Hydrocortisone in Congenital Adrenal Hyperplasia.
Merke DP, Mallappa A, Arlt W, Brac de la Perriere A, Lindén Hirschberg A, Juul A, Newell-Price J, Perry CG, Prete A, Rees DA, Reisch N, Stikkelbroeck N, Touraine P, Maltby K, Treasure FP, Porter J, Ross RJ. Merke DP, et al. J Clin Endocrinol Metab. 2021 Apr 23;106(5):e2063-e2077. doi: 10.1210/clinem/dgab051. J Clin Endocrinol Metab. 2021. PMID: 33527139 Free PMC article. Clinical Trial.
CONTEXT: Standard glucocorticoid therapy in congenital adrenal hyperplasia (CAH) regularly fails to control androgen excess, causing glucocorticoid overexposure and poor health outcomes. OBJECTIVE: We investigated whether modified-release hydrocortisone (MR-HC), which mimi …
CONTEXT: Standard glucocorticoid therapy in congenital adrenal hyperplasia (CAH) regularly fails to control androgen excess, causing glucoco …
Effect of treatment with low doses of hydrocortisone and fludrocortisone on mortality in patients with septic shock.
Annane D, Sébille V, Charpentier C, Bollaert PE, François B, Korach JM, Capellier G, Cohen Y, Azoulay E, Troché G, Chaumet-Riffaud P, Bellissant E. Annane D, et al. JAMA. 2002 Aug 21;288(7):862-71. doi: 10.1001/jama.288.7.862. JAMA. 2002. PMID: 12186604 Clinical Trial.
INTERVENTION: Patients were randomly assigned to receive either hydrocortisone (50-mg intravenous bolus every 6 hours) and fludrocortisone (50- micro g tablet once daily) (n = 151) or matching placebos (n = 149) for 7 days. ...CONCLUSION: In our trial, a 7-day treatment wi …
INTERVENTION: Patients were randomly assigned to receive either hydrocortisone (50-mg intravenous bolus every 6 hours) and fludrocort …
Effect of early low-dose hydrocortisone on survival without bronchopulmonary dysplasia in extremely preterm infants (PREMILOC): a double-blind, placebo-controlled, multicentre, randomised trial.
Baud O, Maury L, Lebail F, Ramful D, El Moussawi F, Nicaise C, Zupan-Simunek V, Coursol A, Beuchée A, Bolot P, Andrini P, Mohamed D, Alberti C; PREMILOC trial study group. Baud O, et al. Lancet. 2016 Apr 30;387(10030):1827-36. doi: 10.1016/S0140-6736(16)00202-6. Epub 2016 Feb 23. Lancet. 2016. PMID: 26916176 Clinical Trial.
In this study, we aimed to assess whether low-dose hydrocortisone improved survival without bronchopulmonary dysplasia in extremely preterm infants. ...FINDINGS: 1072 neonates were screened between May 25, 2008, and Jan 31, 2014, of which 523 were randomly assigned (256 …
In this study, we aimed to assess whether low-dose hydrocortisone improved survival without bronchopulmonary dysplasia in extremely p …
Effects of hydrocortisone combined with vitamin C and vitamin B1 versus hydrocortisone alone on microcirculation in septic shock patients: A pilot study.
Wang J, Song Q, Yang S, Wang H, Meng S, Huang L, Li Q, Xu J, Xie J, Huang Y. Wang J, et al. Clin Hemorheol Microcirc. 2023;84(2):111-123. doi: 10.3233/CH-221444. Clin Hemorheol Microcirc. 2023. PMID: 36911931 Free PMC article. Clinical Trial.
OBJECTIVE: To investigate the effects of hydrocortisone combined with vitamin C and vitamin B1 versus hydrocortisone on sublingual microcirculation in septic shock patients. ...We randomly assigned the enrolled patients to the treatment group (hydrocortisone
OBJECTIVE: To investigate the effects of hydrocortisone combined with vitamin C and vitamin B1 versus hydrocortisone on sublin …
Hippocampal Mechanisms Support Cortisol-Induced Memory Enhancements.
Sherman BE, Harris BB, Turk-Browne NB, Sinha R, Goldfarb EV. Sherman BE, et al. J Neurosci. 2023 Oct 25;43(43):7198-7212. doi: 10.1523/JNEUROSCI.0916-23.2023. Epub 2023 Oct 9. J Neurosci. 2023. PMID: 37813570 Free PMC article. Clinical Trial.
Neurally, hydrocortisone led to enhanced functional connectivity between hippocampal subregions, which predicted subsequent memory enhancements for emotional associations. ...In the current study, we combined functional neuroimaging, behavioral tests of memory, and double- …
Neurally, hydrocortisone led to enhanced functional connectivity between hippocampal subregions, which predicted subsequent memory en …
Residual endogenous corticosteroid production in patients with adrenal insufficiency.
Vulto A, Bergthorsdottir R, van Faassen M, Kema IP, Johannsson G, van Beek AP. Vulto A, et al. Clin Endocrinol (Oxf). 2019 Sep;91(3):383-390. doi: 10.1111/cen.14006. Epub 2019 Jun 20. Clin Endocrinol (Oxf). 2019. PMID: 31059146 Free PMC article. Clinical Trial.
PATIENTS AND MEASUREMENTS: Patients with primary adrenal insufficiency were on stable hydrocortisone and fludrocortisone therapy. Patients with secondary adrenal insufficiency received two different doses of hydrocortisone in a randomized crossover study. Main outco …
PATIENTS AND MEASUREMENTS: Patients with primary adrenal insufficiency were on stable hydrocortisone and fludrocortisone therapy. Pat …
Long-term costs and cost-effectiveness of adjunctive corticosteroids for patients with septic shock in New Zealand.
Thompson KJ, Young PJ, Venkatesh B, Cohen J, Finfer SR, Grattan S, Hammond NE, Jan S, Li Q, Di Tanna GL, McArthur C, Myburgh J, Rajbhandari D, Taylor CB. Thompson KJ, et al. Aust Crit Care. 2022 May;35(3):241-250. doi: 10.1016/j.aucc.2021.05.006. Epub 2021 Jul 26. Aust Crit Care. 2022. PMID: 34325975 Clinical Trial.
The mean total costs per patient over 24 months were $143,627 100,890 and $143,772 97,117 for the hydrocortisone and placebo groups, respectively (p = 0.99). Intensive care unit costs for the index admission were $50,492 and $62,288 per patient for the hydrocortisone
The mean total costs per patient over 24 months were $143,627 100,890 and $143,772 97,117 for the hydrocortisone and placebo groups, …
A randomized clinical trial on inhaled ciclesonide for managing acute asthma in the emergency room.
Martins DT, Carlos K, Carvalho LB, Prado LB, Fransolin C, Atallah AN, Prado GFD. Martins DT, et al. Sao Paulo Med J. 2022 May-Jun;140(3):430-438. doi: 10.1590/1516-3180.2021.0542.R1.15092021. Sao Paulo Med J. 2022. PMID: 35508008 Free PMC article. Clinical Trial.
OBJECTIVE: To compare high doses of inhaled ciclesonide with systemic hydrocortisone for managing acute asthma exacerbations in the emergency department. ...Over the course of four hours, one group received 1440 mcg of inhaled ciclesonide plus hydrocortisone-identic …
OBJECTIVE: To compare high doses of inhaled ciclesonide with systemic hydrocortisone for managing acute asthma exacerbations in the e …
Preinterventional hydrocortisone sustains the endothelial glycocalyx in cardiac surgery.
Brettner F, Chappell D, Nebelsiek T, Hauer D, Schelling G, Becker BF, Rehm M, Weis F. Brettner F, et al. Clin Hemorheol Microcirc. 2019;71(1):59-70. doi: 10.3233/CH-180384. Clin Hemorheol Microcirc. 2019. PMID: 29843226 Clinical Trial.
One main pathomechanism leading to the edema is the deterioration of the endothelial glycocalyx, a key component of the vascular barrier. In animal models hydrocortisone has proved to be protective for the glycocalyx. OBJECTIVE: This trial evaluates the effect of hydroc
One main pathomechanism leading to the edema is the deterioration of the endothelial glycocalyx, a key component of the vascular barrier. In …
Pharmacokinetics of oral hydrocortisone - Results and implications from a randomized controlled trial.
Werumeus Buning J, Touw DJ, Brummelman P, Dullaart RPF, van den Berg G, van der Klauw MM, Kamp J, Wolffenbuttel BHR, van Beek AP. Werumeus Buning J, et al. Metabolism. 2017 Jun;71:7-16. doi: 10.1016/j.metabol.2017.02.005. Epub 2017 Feb 13. Metabolism. 2017. PMID: 28521880 Clinical Trial.
CONTEXT AND OBJECTIVE: This study aimed at comparing pharmacokinetics of two different doses of hydrocortisone (HC) in patients with secondary adrenal insufficiency (SAI). ...
CONTEXT AND OBJECTIVE: This study aimed at comparing pharmacokinetics of two different doses of hydrocortisone (HC) in patients with …
8,407 results