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A stability indicating RP-HPLC-UV assay method for the simultaneous determination of hydroquinone, tretinoin, hydrocortisone, butylated hydroxytoluene and parabens in pharmaceutical creams.
Khairy MA, Hamad A, Hamed M, Locatelli M, Mansour FR. Khairy MA, et al. J Pharm Biomed Anal. 2024 May 15;242:116021. doi: 10.1016/j.jpba.2024.116021. Epub 2024 Feb 8. J Pharm Biomed Anal. 2024. PMID: 38354540 Free article.
In this work, a stability indicating assay method was developed and validated (according to the ICH International Guidelines) for the simultaneous determination of hydroquinone (HQ), tretinoin (TRT), hydrocortisone (HCA), butylated hydroxytoluene (BHT), methy …
In this work, a stability indicating assay method was developed and validated (according to the ICH International Guidelines) for the simult …
A New HPLC-DAD Method for the Concurrent Determination of Hydroquinone, Hydrocortisone Acetate and Tretinoin in Different Pharmaceuticals for Melasma Treatment.
Ibrahim F, Sharaf El-Din MK, El-Deen AK, Shimizu K. Ibrahim F, et al. J Chromatogr Sci. 2019 Jul 1;57(6):495-501. doi: 10.1093/chromsci/bmz020. J Chromatogr Sci. 2019. PMID: 30941396
A new simple and robust HPLC-DAD method was developed for the concurrent analysis of hydroquinone (HQ), hydrocortisone acetate (HCA) and tretinoin (TRN) triple combination for the first time using an Inertsil ODS 3-C18 column (150 mm 4.6 mm, 5 mum particle si …
A new simple and robust HPLC-DAD method was developed for the concurrent analysis of hydroquinone (HQ), hydrocortisone acetate …
Efficacy of combination of glycolic acid peeling with topical regimen in treatment of melasma.
Chaudhary S, Dayal S. Chaudhary S, et al. J Drugs Dermatol. 2013 Oct;12(10):1149-53. J Drugs Dermatol. 2013. PMID: 24085051 Clinical Trial.
OBJECTIVE: To assess the efficacy of combination of topical regimen (2% hydroquinone, 1% hydrocortisone and 0.05% tretinoin) with serial glycolic acid peeling in the treatment of melasma in Indian patients. ...One Group i.e. peel group received topical regime …
OBJECTIVE: To assess the efficacy of combination of topical regimen (2% hydroquinone, 1% hydrocortisone and 0.05% tretinoin …
Intermittent therapy for melasma in Asian patients with combined topical agents (retinoic acid, hydroquinone and hydrocortisone): clinical and histological studies.
Kang WH, Chun SC, Lee S. Kang WH, et al. J Dermatol. 1998 Sep;25(9):587-96. doi: 10.1111/j.1346-8138.1998.tb02463.x. J Dermatol. 1998. PMID: 9798345 Clinical Trial.
In the present study, we evaluated the efficacy of a new formula containing 0.1% tretinoin, 5% hydroquinone, and 1% hydrocortisone (RHQ) in Korean patients with melasma. ...
In the present study, we evaluated the efficacy of a new formula containing 0.1% tretinoin, 5% hydroquinone, and 1% hydroco …
Effects of all-trans retinoic acid on melanogenesis in pigmented skin equivalents and monolayer culture of melanocytes.
Yoshimura K, Tsukamoto K, Okazaki M, Virador VM, Lei TC, Suzuki Y, Uchida G, Kitano Y, Harii K. Yoshimura K, et al. J Dermatol Sci. 2001 Aug;27 Suppl 1:S68-75. doi: 10.1016/s0923-1811(01)00116-5. J Dermatol Sci. 2001. PMID: 11514127
The purpose of this study was to determine the effects of RA on melanogenesis in the pigmented skin equivalent as well as in monolayer culture of melanocytes, and to determine whether RA, hydroquinone (HQ), and hydrocortisone (HC) show synergistic depigmenting effec …
The purpose of this study was to determine the effects of RA on melanogenesis in the pigmented skin equivalent as well as in monolayer cultu …
A new formula for depigmenting human skin.
Kligman AM, Willis I. Kligman AM, et al. Arch Dermatol. 1975 Jan;111(1):40-8. Arch Dermatol. 1975. PMID: 1119822
Complete depigmentation of the noraml skin of adult male blacks was procured by the daily application for five to seven weeks of a formula consisting of 0.1% tretinoin, 5.0% hydroquinone, 0.1% dexamethasone, and hydrophilic ointment. Depigmentation was not attainabl …
Complete depigmentation of the noraml skin of adult male blacks was procured by the daily application for five to seven weeks of a formula c …
Mathematical filtration of quaternary mixture to the zero order spectra of its individual components.
Fahmy NM, Hesham K, Tawakkol SM, AbdelAziz L, Abdelrahman MH. Fahmy NM, et al. Spectrochim Acta A Mol Biomol Spectrosc. 2021 Nov 15;261:119999. doi: 10.1016/j.saa.2021.119999. Epub 2021 May 25. Spectrochim Acta A Mol Biomol Spectrosc. 2021. PMID: 34091362
Simple accurate and precise validated UV spectrophotometric methods have been described here for the simultaneous determination of Tretinoin (TN) Eusolex (EX) Hydroquinone (HQ) & Hydrocortisone acetate (HC) in their dosage form. ...
Simple accurate and precise validated UV spectrophotometric methods have been described here for the simultaneous determination of Tretin …
A Treatment Combination of Peels, Oral Antioxidants, and Topical Therapy for Refractory Melasma: A Report of 4 Cases.
Piquero-Casals J, Granger C, Piquero-Casals V, Garre A, Mir-Bonafé JF. Piquero-Casals J, et al. Clin Cosmet Investig Dermatol. 2020 Mar 4;13:209-213. doi: 10.2147/CCID.S242180. eCollection 2020. Clin Cosmet Investig Dermatol. 2020. PMID: 32161485 Free PMC article.
PATIENTS AND METHODS: We present four cases of patients with melasma, who, despite multiple treatments including hydroquinone, showed no improvement. We initiated a 16-week protocol involving 3 in-clinic peels (4 weeks apart) and a daily home treatment. ...The home treatme …
PATIENTS AND METHODS: We present four cases of patients with melasma, who, despite multiple treatments including hydroquinone, showed …
Resurfacing of pitted facial scars with a pulsed Er:YAG laser.
Kye YC. Kye YC. Dermatol Surg. 1997 Oct;23(10):880-3. doi: 10.1111/j.1524-4725.1997.tb00740.x. Dermatol Surg. 1997. PMID: 9357495
All patients were skin type III and IV. All patients were instructed to use tretinoin cream 0.05% nightly for 2-4 weeks prior to the laser treatment. The pulsed Er:YAG laser with 2-mm handpiece at the setting of 500 mJ/pulse, 3.5-4.5 W was used. Two weeks after laser treat …
All patients were skin type III and IV. All patients were instructed to use tretinoin cream 0.05% nightly for 2-4 weeks prior to the …
The combination of glycolic acid peels with a topical regimen in the treatment of melasma in dark-skinned patients: a comparative study.
Sarkar R, Kaur C, Bhalla M, Kanwar AJ. Sarkar R, et al. Dermatol Surg. 2002 Sep;28(9):828-32; discussion 832. doi: 10.1046/j.1524-4725.2002.02034.x. Dermatol Surg. 2002. PMID: 12269877 Clinical Trial.
BACKGROUND: Melasma continues to be a difficult condition to treat, especially in dark-skinned patients, although various topical modalities including hydroquinone, tretinoin, and/or topical steroids have been used singly or in combination with variable results. OBJ …
BACKGROUND: Melasma continues to be a difficult condition to treat, especially in dark-skinned patients, although various topical modalities …
15 results