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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1919 1
1929 1
1941 1
1945 2
1946 2
1947 9
1948 8
1949 9
1950 1
1951 3
1952 6
1953 9
1954 1
1955 5
1956 7
1957 5
1958 7
1959 5
1960 10
1961 17
1962 8
1963 10
1964 22
1965 25
1966 28
1967 35
1968 40
1969 55
1970 55
1971 48
1972 55
1973 38
1974 42
1975 47
1976 53
1977 35
1978 30
1979 45
1980 52
1981 46
1982 51
1983 47
1984 49
1985 79
1986 95
1987 84
1988 89
1989 89
1990 131
1991 147
1992 142
1993 152
1994 149
1995 171
1996 180
1997 159
1998 172
1999 177
2000 190
2001 201
2002 191
2003 196
2004 229
2005 266
2006 267
2007 286
2008 276
2009 291
2010 291
2011 315
2012 311
2013 334
2014 325
2015 294
2016 350
2017 317
2018 299
2019 316
2020 339
2021 361
2022 374
2023 335
2024 164

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9,341 results

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Page 1
Management of hyperpigmentation: Current treatments and emerging therapies.
Nautiyal A, Wairkar S. Nautiyal A, et al. Pigment Cell Melanoma Res. 2021 Nov;34(6):1000-1014. doi: 10.1111/pcmr.12986. Epub 2021 Jun 3. Pigment Cell Melanoma Res. 2021. PMID: 33998768 Review.
The first-line treatment for hyperpigmentation involves topical formulations of conventional agents such as hydroquinone, kojic acid, and glycolic acid followed by oral formulations of therapeutic agents such as tranexamic acid, melatonin, and cysteamine hydrochloride. ...
The first-line treatment for hyperpigmentation involves topical formulations of conventional agents such as hydroquinone, kojic acid, …
Hyperpigmentation: Looking beyond hydroquinone.
Charoo NA. Charoo NA. J Cosmet Dermatol. 2022 Oct;21(10):4133-4145. doi: 10.1111/jocd.14746. Epub 2022 Jan 12. J Cosmet Dermatol. 2022. PMID: 35020267 Review.
Prolonged use of hydroquinone has been associated with cancer risk and exogenous ochronosis. ...Alternative treatment options to hydroquinone in clinical practice are reviewed in this paper with regard to their safety and efficacy vis a vis hydroquinone. ...
Prolonged use of hydroquinone has been associated with cancer risk and exogenous ochronosis. ...Alternative treatment options to h
Hydroquinone: myths and reality.
Searle T, Al-Niaimi F, Ali FR. Searle T, et al. Clin Exp Dermatol. 2021 Jun;46(4):636-640. doi: 10.1111/ced.14480. Epub 2020 Nov 7. Clin Exp Dermatol. 2021. PMID: 33159818 Review.
Hydroquinone has pharmacological uses in disorders of pigmentation because of its ability to competitively inhibit the enzyme tyrosinase. Our contemporary review presents the strongest evidence supporting the use of hydroquinone with the most effective and tolerable
Hydroquinone has pharmacological uses in disorders of pigmentation because of its ability to competitively inhibit the enzyme tyrosin
An update on the safety of hydroquinone.
Shivaram K, Edwards K, Mohammad TF. Shivaram K, et al. Arch Dermatol Res. 2024 Jun 8;316(7):378. doi: 10.1007/s00403-024-02990-6. Arch Dermatol Res. 2024. PMID: 38850450 Review.
Hydroquinone has been used for years for multiple conditions, including melasma, post-inflammatory hyperpigmentation, dyschromia from photoaging, and solar lentigines. ...While there have been prior informative, large-scale reviews on the safety of hydroquinone, new
Hydroquinone has been used for years for multiple conditions, including melasma, post-inflammatory hyperpigmentation, dyschromia from
Hydroquinone.
[No authors listed] [No authors listed] IARC Monogr Eval Carcinog Risks Hum. 1999;71 Pt 2(PT 2):691-719. IARC Monogr Eval Carcinog Risks Hum. 1999. PMID: 10476468 Free PMC article. Review. No abstract available.
The safety of hydroquinone.
Nordlund JJ, Grimes PE, Ortonne JP. Nordlund JJ, et al. J Eur Acad Dermatol Venereol. 2006 Aug;20(7):781-7. doi: 10.1111/j.1468-3083.2006.01670.x. J Eur Acad Dermatol Venereol. 2006. PMID: 16898897 Review.
Hydroquinone is one of the most effective molecules for the treatment of hyperpigmentary disorders, with over 40 years of efficacy and safety data. ...This article reviews the evidence for the safety of hydroquinone in the treatment of hyperpigmentation conditions..
Hydroquinone is one of the most effective molecules for the treatment of hyperpigmentary disorders, with over 40 years of efficacy an
Hydroquinone: environmental pollution, toxicity, and microbial answers.
Enguita FJ, Leitão AL. Enguita FJ, et al. Biomed Res Int. 2013;2013:542168. doi: 10.1155/2013/542168. Epub 2013 Jul 15. Biomed Res Int. 2013. PMID: 23936816 Free PMC article. Review.
Human exposure to hydroquinone can occur by dietary, occupational, and environmental sources. ...Due to the recent research development on hydroquinone, this review underscores not only the mechanisms of hydroquinone biotransformation and the role of microorg …
Human exposure to hydroquinone can occur by dietary, occupational, and environmental sources. ...Due to the recent research developme …
Antimicrobial Mechanism of Hydroquinone.
Ma C, He N, Zhao Y, Xia D, Wei J, Kang W. Ma C, et al. Appl Biochem Biotechnol. 2019 Dec;189(4):1291-1303. doi: 10.1007/s12010-019-03067-1. Epub 2019 Jun 28. Appl Biochem Biotechnol. 2019. PMID: 31254228
The antibacterial mechanism of hydroquinone had been explored by scanning electron microscopy (SEM), alkaline phosphatase (AKP), and bacterial extracellular protein leakage. Results showed that hydroquinone could destroy the bacterial cell wall and membrane, increas …
The antibacterial mechanism of hydroquinone had been explored by scanning electron microscopy (SEM), alkaline phosphatase (AKP), and …
Skin bleaching: highlighting the misuse of cutaneous depigmenting agents.
Dadzie OE, Petit A. Dadzie OE, et al. J Eur Acad Dermatol Venereol. 2009 Jul;23(7):741-50. doi: 10.1111/j.1468-3083.2009.03150.x. Epub 2009 Mar 11. J Eur Acad Dermatol Venereol. 2009. PMID: 19470077 Review.
Hydroquinone and other cutaneous depigmenting agents are widely used by dermatologists to treat pigmentary disorders. ...Thus, this current discussion within the dermatological community on the safety of hydroquinone provides a unique opportunity to raise awareness
Hydroquinone and other cutaneous depigmenting agents are widely used by dermatologists to treat pigmentary disorders. ...Thus, this c
Biophysical radiosensitization.
Vladescu C, Apetroae M. Vladescu C, et al. Radiat Environ Biophys. 1983;22(2):141-8. doi: 10.1007/BF01338892. Radiat Environ Biophys. 1983. PMID: 6611847
Hydroquinone treatment produces a specific inhibition of catalase in the tumor and a higher degree of oxygenation at this level. ...The oxygenation of the hypoxic tumoral tissue is done at non-toxic levels of hydroquinone, through a natural and specific biophysical
Hydroquinone treatment produces a specific inhibition of catalase in the tumor and a higher degree of oxygenation at this level. ...T
9,341 results