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Year Number of Results
1954 1
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1963 1
1964 2
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1975 1
1976 1
1977 3
1979 2
1980 1
1982 3
1983 3
1984 1
1985 4
1986 5
1987 4
1988 3
1989 3
1990 10
1991 8
1992 6
1993 4
1994 8
1995 10
1996 9
1997 13
1998 6
1999 8
2000 8
2001 10
2002 8
2003 11
2004 14
2005 14
2006 11
2007 12
2008 11
2009 19
2010 18
2011 17
2012 18
2013 21
2014 17
2015 19
2016 11
2017 16
2018 7
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2020 11
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2022 14
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419 results

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Page 1
How many carbonic anhydrase inhibition mechanisms exist?
Supuran CT. Supuran CT. J Enzyme Inhib Med Chem. 2016;31(3):345-60. doi: 10.3109/14756366.2015.1122001. Epub 2015 Nov 30. J Enzyme Inhib Med Chem. 2016. PMID: 26619898 Free article. Review.
Sulfonamides and their isosters, most anions, dithiocarbamates and their isosters, carboxylates, and hydroxamates bind in this way; (ii) inhibitors that anchor to the zinc-coordinated water molecule/hydroxide ion (phenols, carboxylates, polyamines, 2-thioxocoumarins …
Sulfonamides and their isosters, most anions, dithiocarbamates and their isosters, carboxylates, and hydroxamates bind in this way; (ii) inh …
The role of the chemical burns caused by hydroxide ion in the toxicity of dermal exposure to tetramethylammonium ion in a rat model.
Wu CL, Su SB, Lien HY, Guo HR. Wu CL, et al. Burns. 2012 Nov;38(7):1051-7. doi: 10.1016/j.burns.2012.02.027. Epub 2012 Jun 13. Burns. 2012. PMID: 22698842
OBJECTIVE: To evaluate the role of the chemical burns caused by hydroxide ion in the fatal effects of tetramethylammonium ion (TMA) in dermal exposure to tetramethylammonium hydroxide (TMAH), we conducted a rat study consisting of two-step treatments with dermal exp …
OBJECTIVE: To evaluate the role of the chemical burns caused by hydroxide ion in the fatal effects of tetramethylammonium ion …
Carbonic anhydrases as targets for medicinal chemistry.
Supuran CT, Scozzafava A. Supuran CT, et al. Bioorg Med Chem. 2007 Jul 1;15(13):4336-50. doi: 10.1016/j.bmc.2007.04.020. Epub 2007 Apr 19. Bioorg Med Chem. 2007. PMID: 17475500 Review.
The catalytic mechanism of the alpha-CAs is understood in detail: the active site consists of a Zn(II) ion co-ordinated by three histidine residues and a water molecule/hydroxide ion. The latter is the active species, acting as a potent nucleophile. For beta- and ga …
The catalytic mechanism of the alpha-CAs is understood in detail: the active site consists of a Zn(II) ion co-ordinated by three histidine r …
419 results