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1943 2
1945 1
1946 1
1948 1
1949 1
1951 1
1952 2
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1954 3
1955 2
1956 3
1957 2
1958 1
1959 2
1961 2
1962 1
1964 3
1965 8
1966 2
1967 6
1968 4
1969 8
1970 9
1971 3
1972 1
1973 5
1974 2
1975 7
1976 3
1977 4
1978 7
1979 3
1980 7
1981 7
1982 10
1983 4
1984 5
1985 3
1986 6
1987 12
1988 1
1989 7
1990 5
1991 13
1992 7
1993 7
1994 12
1995 9
1996 7
1997 8
1998 14
1999 16
2000 12
2001 10
2002 12
2003 10
2004 7
2005 16
2006 17
2007 11
2008 14
2009 14
2010 15
2011 13
2012 18
2013 10
2014 15
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599 results

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Page 1
Hyoscyamine.
[No authors listed] [No authors listed] 2017 Jul 7. LiverTox: Clinical and Research Information on Drug-Induced Liver Injury [Internet]. Bethesda (MD): National Institute of Diabetes and Digestive and Kidney Diseases; 2012–. 2017 Jul 7. LiverTox: Clinical and Research Information on Drug-Induced Liver Injury [Internet]. Bethesda (MD): National Institute of Diabetes and Digestive and Kidney Diseases; 2012–. PMID: 31644177 Free Books & Documents. Review.
Hyoscyamine as a natural plant alkaloid derivative and anticholinergic that is used to treat mild to moderate nausea, motion sickness, hyperactive bladder and allergic rhinitis. Hyoscyamine has not been implicated in causing liver enzyme elevations or clinically app …
Hyoscyamine as a natural plant alkaloid derivative and anticholinergic that is used to treat mild to moderate nausea, motion sickness …
Nightshade Vegetables: A Dietary Trigger for Worsening Inflammatory Bowel Disease and Irritable Bowel Syndrome?
Kuang R, Levinthal DJ, Ghaffari AA, Del Aguila de Rivers CR, Tansel A, Binion DG. Kuang R, et al. Dig Dis Sci. 2023 Jul;68(7):2853-2860. doi: 10.1007/s10620-023-07955-9. Epub 2023 May 19. Dig Dis Sci. 2023. PMID: 37202602 Review.
Many pharmacologically active compounds used in traditional medicine, including atropine and hyoscyamine, are derived from Nightshades. In addition to these beneficial pharmacologic agents, Nightshade-derived glycoalkaloid compounds, a key defense mechanism against predati …
Many pharmacologically active compounds used in traditional medicine, including atropine and hyoscyamine, are derived from Nightshade …
Antiemetic Agents.
[No authors listed] [No authors listed] 2018 Jan 15. LiverTox: Clinical and Research Information on Drug-Induced Liver Injury [Internet]. Bethesda (MD): National Institute of Diabetes and Digestive and Kidney Diseases; 2012–. 2018 Jan 15. LiverTox: Clinical and Research Information on Drug-Induced Liver Injury [Internet]. Bethesda (MD): National Institute of Diabetes and Digestive and Kidney Diseases; 2012–. PMID: 31643401 Free Books & Documents. Review.
Nevertheless, some anticholinergics are used alone or in combination with other agents for mild nausea and vomiting, including scopolamine and hyoscyamine. Phenothiazines, which are typically used as antipsychotic medications, also have antiemetic effects and several minor …
Nevertheless, some anticholinergics are used alone or in combination with other agents for mild nausea and vomiting, including scopolamine a …
Nocturnal enuresis.
Kiddoo D. Kiddoo D. BMJ Clin Evid. 2011 Jan 31;2011:0305. BMJ Clin Evid. 2011. PMID: 21477399 Free PMC article. Review.
CONCLUSIONS: In this systematic review we present information relating to the effectiveness and safety of the following interventions: acupuncture, anticholinergics (oxybutynin, tolterodine, hyoscyamine), desmopressin, dry bed training, enuresis alarm, hypnotherapy, standa …
CONCLUSIONS: In this systematic review we present information relating to the effectiveness and safety of the following interventions: acupu …
Engineered Microbes for Producing Anticholinergics.
Courdavault V, Cassereau J, Papon N. Courdavault V, et al. Chembiochem. 2021 Apr 16;22(8):1368-1370. doi: 10.1002/cbic.202000757. Epub 2020 Dec 17. Chembiochem. 2021. PMID: 33215811 Review.
The tropane alkaloids (TAs) hyoscyamine and scopolamine function as acetylcholine receptor antagonists and are used clinically as parasympatholytics to treat neuromuscular disorders in humans. ...Based on the landmark microbial production of the antimalarial semi-synthetic …
The tropane alkaloids (TAs) hyoscyamine and scopolamine function as acetylcholine receptor antagonists and are used clinically as par …
Nocturnal enuresis.
Kiddoo D. Kiddoo D. BMJ Clin Evid. 2007 Oct 1;2007:0305. BMJ Clin Evid. 2007. PMID: 19450363 Free PMC article. Review.
CONCLUSIONS: In this systematic review we present information relating to the effectiveness and safety of the following interventions: acupuncture, anticholinergics (oxybutynin, tolterodine, hyoscyamine), desmopression, dry bed training, enuresis alarm, hypnotherapy, stand …
CONCLUSIONS: In this systematic review we present information relating to the effectiveness and safety of the following interventions: acupu …
Tropane alkaloid biosynthesis: a centennial review.
Huang JP, Wang YJ, Tian T, Wang L, Yan Y, Huang SX. Huang JP, et al. Nat Prod Rep. 2021 Sep 23;38(9):1634-1658. doi: 10.1039/d0np00076k. Nat Prod Rep. 2021. PMID: 33533391 Review.
Covering: 1917 to 2020Tropane alkaloids (TAs) are a remarkable class of plant secondary metabolites, which are characterized by an 8-azabicyclo[3.2.1]octane (nortropane) ring. Members of this class, such as hyoscyamine, scopolamine, and cocaine, are well known for their lo …
Covering: 1917 to 2020Tropane alkaloids (TAs) are a remarkable class of plant secondary metabolites, which are characterized by an 8-azabicy …
The Evolutionary Pattern of Cocaine and Hyoscyamine Biosynthesis Provides Strategies To Produce Tropane Alkaloids.
Zamar DL, Papon N, Courdavault V. Zamar DL, et al. Chembiochem. 2023 Sep 15;24(18):e202300234. doi: 10.1002/cbic.202300234. Epub 2023 Aug 11. Chembiochem. 2023. PMID: 37249120 Review.
Cocaine and hyoscyamine are two tropane alkaloids (TA) from Erythroxylaceae and Solanaceae, respectively. These famous compounds possess anticholinergic properties that can be used to treat neuromuscular disorders. While the hyoscyamine biosynthetic pathway has been …
Cocaine and hyoscyamine are two tropane alkaloids (TA) from Erythroxylaceae and Solanaceae, respectively. These famous compounds poss …
Biosynthesis of medicinal tropane alkaloids in yeast.
Srinivasan P, Smolke CD. Srinivasan P, et al. Nature. 2020 Sep;585(7826):614-619. doi: 10.1038/s41586-020-2650-9. Epub 2020 Sep 2. Nature. 2020. PMID: 32879484 Free PMC article.
Here we engineered baker's yeast to produce the medicinal alkaloids hyoscyamine and scopolamine, starting from simple sugars and amino acids. We combined functional genomics to identify a missing pathway enzyme, protein engineering to enable the functional expression of an …
Here we engineered baker's yeast to produce the medicinal alkaloids hyoscyamine and scopolamine, starting from simple sugars and amin …
Hyoscyamine induces developmental toxicity by disrupting metabolism in zebrafish embryo (Danio rerio).
Lv Y, Lin Z, Chen J, Jiang K, Wang A, Wang B, Wu Y, Xu Z, Wang J, Yao W. Lv Y, et al. Food Chem Toxicol. 2023 Jul;177:113860. doi: 10.1016/j.fct.2023.113860. Epub 2023 May 30. Food Chem Toxicol. 2023. PMID: 37263572
Hyoscyamine is a kind of tropane alkaloids, which exists in several plants of the family Solanaceae. However, the mechanism underlying such hyoscyamine toxic effects during early development remains unclear. In this study, an untargeted metabolomics approach was use …
Hyoscyamine is a kind of tropane alkaloids, which exists in several plants of the family Solanaceae. However, the mechanism underlyin …
599 results