Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My Custom Filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1965 1
1968 1
1969 1
1970 2
1975 1
1977 1
1980 1
1981 3
1982 2
1985 1
1990 1
1992 1
1993 1
1997 1
1998 3
1999 5
2001 1
2002 2
2006 1
2007 1
2008 1
2014 1
2022 1
2024 1

Publication date

Text availability

Article attribute

Article type

Additional filters

Article Language

Species

Sex

Age

Other

Search Results

35 results

Results by year

Filters applied: . Clear all
Page 1
Effect of Open-label Placebo on Children and Adolescents With Functional Abdominal Pain or Irritable Bowel Syndrome: A Randomized Clinical Trial.
Nurko S, Saps M, Kossowsky J, Zion SR, Di Lorenzo C, Vaz K, Hawthorne K, Wu R, Ciciora S, Rosen JM, Kaptchuk TJ, Kelley JM. Nurko S, et al. JAMA Pediatr. 2022 Apr 1;176(4):349-356. doi: 10.1001/jamapediatrics.2021.5750. JAMA Pediatr. 2022. PMID: 35099543 Free PMC article. Clinical Trial.
A standardized method for explaining the OLP was used, and the interaction with clinicians had the same duration and style for both time periods. Hyoscyamine was allowed as a rescue medication. MAIN OUTCOMES AND MEASURES: The primary outcome was the mean daily pain score d …
A standardized method for explaining the OLP was used, and the interaction with clinicians had the same duration and style for both time per …
A controlled trial of glycopyrronium and l-hyoscyamine in the long-term treatment of duodenal ulcer.
Kaye MD, Rhodes J, Beck P, Sweetnam PM, Davies GT, Evans KT. Kaye MD, et al. Gut. 1970 Jul;11(7):559-66. doi: 10.1136/gut.11.7.559. Gut. 1970. PMID: 4916211 Free PMC article. Clinical Trial.
They received either glycopyrronium, or 1-hyoscyamine in a sustained-release form, or inert tablets for one year. Progress was judged on the basis of frequency and severity of symptoms, monthly assessments by patients, antacid consumption, and radiology. By all criteria, g …
They received either glycopyrronium, or 1-hyoscyamine in a sustained-release form, or inert tablets for one year. Progress was judged …
Intramuscular atropine in healthy volunteers: a pharmacokinetic and pharmacodynamic study.
Kentala E, Kaila T, Iisalo E, Kanto J. Kentala E, et al. Int J Clin Pharmacol Ther Toxicol. 1990 Sep;28(9):399-404. Int J Clin Pharmacol Ther Toxicol. 1990. PMID: 2228327 Clinical Trial.
The absorption rate and the elimination rate of dl-hyoscyamine and l-hyoscyamine were comparable (tmax = 8.40 vs 8.67 min, t1/2el = 2.95 vs 2.43 h, dose 0.02 mg/kg) but the mean maximum plasma concentration of dl-hyoscyamine was 2.9 times and the mean AUC val …
The absorption rate and the elimination rate of dl-hyoscyamine and l-hyoscyamine were comparable (tmax = 8.40 vs 8.67 min, t1/ …
Sublingual L-hyoscyamine for duodenal antimotility during ERCP: a prospective randomized double-blinded study.
Lynch CR, Khandekar S, Lynch SM, Disario JA. Lynch CR, et al. Gastrointest Endosc. 2007 Oct;66(4):748-52. doi: 10.1016/j.gie.2007.02.052. Gastrointest Endosc. 2007. PMID: 17905018 Clinical Trial.
OBJECTIVE: Demonstrate whether pre-ERCP sublingual L-hyoscyamine reduces the amount of glucagon required to complete ERCP. DESIGN: Randomized, double-blinded clinical trial of 200 participants assigned to receive L-hyoscyamine 0.5 mg or a placebo sublingually before …
OBJECTIVE: Demonstrate whether pre-ERCP sublingual L-hyoscyamine reduces the amount of glucagon required to complete ERCP. DESIGN: Ra …
Sublingual hyoscyamine for patient comfort during screening sigmoidoscopy: a randomized, double-blind, placebo-controlled clinical trial.
Dumot JA, Verzola E, Nicol S, Easley KA, Vargo JJ, van Stolk RU. Dumot JA, et al. Gastrointest Endosc. 1998 Sep;48(3):283-6. doi: 10.1016/s0016-5107(98)70192-0. Gastrointest Endosc. 1998. PMID: 9744605 Clinical Trial.
The possible benefit of a well-tolerated, low-cost antispasmodic medication, sublingual hyoscyamine, used before flexible sigmoidoscopy was assessed in a randomized, double-blinded, placebo-controlled trial. ...CONCLUSIONS: In this study, hyoscyamine administered in …
The possible benefit of a well-tolerated, low-cost antispasmodic medication, sublingual hyoscyamine, used before flexible sigmoidosco …
Antispasmodic drugs to reduce discomfort and colonic spasm during barium enemas: comparison of oral hyoscyamine, i.v. glucagon, and no drug.
Bova JG, Jurdi RA, Bennett WF. Bova JG, et al. AJR Am J Roentgenol. 1993 Nov;161(5):965-8. doi: 10.2214/ajr.161.5.8273637. AJR Am J Roentgenol. 1993. PMID: 8273637 Clinical Trial.
SUBJECTS AND METHODS: A total of 349 adult patients undergoing barium enema examinations were randomly assigned in a prospective fashion to one of four groups: (1) no medication (87 patients); (2) 1 mg of IV glucagon (88 patients); (3) 0.125 mg of oral hyoscyamine sulfate …
SUBJECTS AND METHODS: A total of 349 adult patients undergoing barium enema examinations were randomly assigned in a prospective fashion to …
Systemic bioavailability of ocularly applied 1% atropine eyedrops.
Kaila T, Korte JM, Saari KM. Kaila T, et al. Acta Ophthalmol Scand. 1999 Apr;77(2):193-6. doi: 10.1034/j.1600-0420.1999.770215.x. Acta Ophthalmol Scand. 1999. PMID: 10321537 Free article. Clinical Trial.
The plasma concentrations of the biologically active atropine enantiomer, 1-hyoscyamine, were determined using a muscarinic cholinoceptor binding assay. RESULTS: The mean area under the curve from zero to infinitum (AUC0-infinity) for 1-hyoscyamine was 1.862+/-0.580 …
The plasma concentrations of the biologically active atropine enantiomer, 1-hyoscyamine, were determined using a muscarinic cholinoce …
Sublingual hyoscyamine spray as premedication for colonoscopy: a randomized double-blinded placebo-controlled trial.
Chaptini LA, Janec EM, Seltzer G, Peikin S, Elfant AB. Chaptini LA, et al. Am J Surg. 2008 Jul;196(1):51-5. doi: 10.1016/j.amjsurg.2007.06.030. Epub 2008 Apr 24. Am J Surg. 2008. PMID: 18436182 Clinical Trial.
The aim of this study was to determine the effect of sublingual hyoscyamine spray (IB-Stat, Inkine Pharmaceutical) on the performance of colonoscopy. METHODS: One hundred patients undergoing elective colonoscopy were randomized in a double-blind study to receive .25 mg sub …
The aim of this study was to determine the effect of sublingual hyoscyamine spray (IB-Stat, Inkine Pharmaceutical) on the performance …
Prospective study comparing hyoscyamine, doxazosin, and combination therapy for the treatment of urgency and frequency in women.
Serels S, Stein M. Serels S, et al. Neurourol Urodyn. 1998;17(1):31-6. doi: 10.1002/(sici)1520-6777(1998)17:1<31::aid-nau6>3.0.co;2-e. Neurourol Urodyn. 1998. PMID: 9453690 Clinical Trial.
Between September 1994 and October 1995, 34 women aged 28-91 (mean age, 62) received either 0.375 mg of sustained-release hyoscyamine twice a day or 2 mg doxazosin QHS prior to being crossed over to the other drug and/or the combination. ...By urodynamic evaluation, a grea …
Between September 1994 and October 1995, 34 women aged 28-91 (mean age, 62) received either 0.375 mg of sustained-release hyoscyamine …
Comparison of no medication, placebo, and hyoscyamine for reducing pain during a barium enema.
Bova JG, Bhattacharjee N, Jurdi R, Bennett WF. Bova JG, et al. AJR Am J Roentgenol. 1999 May;172(5):1285-7. doi: 10.2214/ajr.172.5.10227503. AJR Am J Roentgenol. 1999. PMID: 10227503 Clinical Trial.
SUBJECTS AND METHODS: Patients were randomized into three groups: no medication, placebo, and sublingual 1-hyoscyamine sulfate. The placebo or hyoscyamine tablet was placed under the tongue 15-30 min before the examination. ...CONCLUSION: Although safe, hyoscyami …
SUBJECTS AND METHODS: Patients were randomized into three groups: no medication, placebo, and sublingual 1-hyoscyamine sulfate. The p …
35 results