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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1967 1
1968 1
1969 2
1970 6
1971 3
1972 5
1973 16
1974 8
1975 14
1976 14
1977 14
1978 23
1979 31
1980 25
1981 16
1982 11
1983 29
1984 36
1985 30
1986 33
1987 30
1988 26
1989 27
1990 47
1991 43
1992 42
1993 33
1994 43
1995 42
1996 38
1997 44
1998 44
1999 40
2000 69
2001 45
2002 48
2003 49
2004 59
2005 49
2006 61
2007 58
2008 76
2009 64
2010 55
2011 69
2012 64
2013 67
2014 54
2015 53
2016 72
2017 94
2018 85
2019 78
2020 75
2021 64
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2,061 results
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Page 1
Ibuprofen versus paracetamol for treating fever in preschool children in Nigeria: a randomized clinical trial of effectiveness and safety.
Alaje EO, Udoh EE, Akande PA, Odey FA, Meremikwu MM. Alaje EO, et al. Pan Afr Med J. 2020 Aug 26;36:350. doi: 10.11604/pamj.2020.36.350.21393. eCollection 2020. Pan Afr Med J. 2020. PMID: 33224416 Free PMC article. Clinical Trial.
INTRODUCTION: fever is the primary symptom of most childhood illnesses and a cause of concern to their caregivers. The antipyretics commonly used to treat fever are ibuprofen and paracetamol. Most studies on the effectiveness of ibuprofen and paracetamol in treating …
INTRODUCTION: fever is the primary symptom of most childhood illnesses and a cause of concern to their caregivers. The antipyretics commonly …
Pharmacokinetics and Bioavailability of a Fixed-Dose Combination of Ibuprofen and Paracetamol after Intravenous and Oral Administration.
Atkinson HC, Stanescu I, Frampton C, Salem II, Beasley CP, Robson R. Atkinson HC, et al. Clin Drug Investig. 2015 Oct;35(10):625-32. doi: 10.1007/s40261-015-0320-8. Clin Drug Investig. 2015. PMID: 26334726 Free PMC article. Clinical Trial.
Serial plasma samples were assayed for both paracetamol and ibuprofen concentrations, using validated liquid chromatography-tandem mass spectrometry methods. ...CONCLUSION: Concomitant administration of 3 mg/mL ibuprofen and 10 mg/mL paracetamol in a fixed-dose IV c …
Serial plasma samples were assayed for both paracetamol and ibuprofen concentrations, using validated liquid chromatography-tandem ma …
Paracetamol plus ibuprofen for the treatment of fever in children (PITCH): randomised controlled trial.
Hay AD, Costelloe C, Redmond NM, Montgomery AA, Fletcher M, Hollinghurst S, Peters TJ. Hay AD, et al. BMJ. 2008 Sep 2;337:a1302. doi: 10.1136/bmj.a1302. BMJ. 2008. PMID: 18765450 Free PMC article. Clinical Trial.
For less time with fever over 24 hours, paracetamol plus ibuprofen were superior to paracetamol (4.4 hours, 2.4 to 6.3; P<0.001) and to ibuprofen (2.5 hours, 0.6 to 4.4; P=0.008). ...CONCLUSION: Parents, nurses, pharmacists, and doctors wanting to use medicines t …
For less time with fever over 24 hours, paracetamol plus ibuprofen were superior to paracetamol (4.4 hours, 2.4 to 6.3; P<0.001) a …
Efficacy and safety of Curcuma domestica extracts compared with ibuprofen in patients with knee osteoarthritis: a multicenter study.
Kuptniratsaikul V, Dajpratham P, Taechaarpornkul W, Buntragulpoontawee M, Lukkanapichonchut P, Chootip C, Saengsuwan J, Tantayakom K, Laongpech S. Kuptniratsaikul V, et al. Clin Interv Aging. 2014 Mar 20;9:451-8. doi: 10.2147/CIA.S58535. eCollection 2014. Clin Interv Aging. 2014. PMID: 24672232 Free PMC article. Clinical Trial.
METHODS: 367 primary knee osteoarthritis patients with a pain score of 5 or higher were randomized to receive ibuprofen 1,200 mg/day or C. domestica extracts 1,500 mg/day for 4 weeks. ...However, the number of events of abdominal pain/discomfort was significantly higher in …
METHODS: 367 primary knee osteoarthritis patients with a pain score of 5 or higher were randomized to receive ibuprofen 1,200 mg/day …
Efficacy and safety of a fixed-dose combination of ibuprofen and caffeine in the management of moderate to severe dental pain after third molar extraction.
Weiser T, Richter E, Hegewisch A, Muse DD, Lange R. Weiser T, et al. Eur J Pain. 2018 Jan;22(1):28-38. doi: 10.1002/ejp.1068. Epub 2017 Aug 14. Eur J Pain. 2018. PMID: 28805281 Free PMC article. Clinical Trial.
Analysis of SPRID0-8 h demonstrated superior analgesic effects for a single dose of ibuprofen/caffeine versus ibuprofen, caffeine and placebo over 8 h, rescue medication in this stage was requested by more patients on ibuprofen (32.5%) than on ibuprofen
Analysis of SPRID0-8 h demonstrated superior analgesic effects for a single dose of ibuprofen/caffeine versus ibuprofen, caffe …
Efficacy and safety of oral paracetamol versus oral ibuprofen for closure of patent ductus arteriosus in preterm infants: a randomized controlled trial.
El-Farrash RA, El Shimy MS, El-Sakka AS, Ahmed MG, Abdel-Moez DG. El-Farrash RA, et al. J Matern Fetal Neonatal Med. 2019 Nov;32(21):3647-3654. doi: 10.1080/14767058.2018.1470235. Epub 2018 May 9. J Matern Fetal Neonatal Med. 2019. PMID: 29695206 Clinical Trial.
Neonates were randomly assigned to two groups: 30 received oral ibuprofen and 30 received oral paracetamol. With failure of ductal closure, a second course of ibuprofen or paracetamol was given. ...Oral paracetamol was comparable with ibuprofen in terms of th …
Neonates were randomly assigned to two groups: 30 received oral ibuprofen and 30 received oral paracetamol. With failure of ductal cl …
Paracetamol and ibuprofen for the treatment of fever in children: the PITCH randomised controlled trial.
Hay AD, Redmond NM, Costelloe C, Montgomery AA, Fletcher M, Hollinghurst S, Peters TJ. Hay AD, et al. Health Technol Assess. 2009 May;13(27):iii-iv, ix-x, 1-163. doi: 10.3310/hta13270. Health Technol Assess. 2009. PMID: 19454182 Free article. Clinical Trial.
OBJECTIVES: To establish the relative clinical effectiveness and cost-effectiveness of paracetamol plus ibuprofen compared with paracetamol and ibuprofen separately for time without fever, and the relief of fever-associated discomfort in young children who can be ma …
OBJECTIVES: To establish the relative clinical effectiveness and cost-effectiveness of paracetamol plus ibuprofen compared with parac …
Single- and Multiple-Dose Pharmacokinetics of Immediate-Release/Extended-Release Ibuprofen Tablets.
Legg T, Paluch E, Jayawardena S. Legg T, et al. Clin Pharmacol Drug Dev. 2017 Jan;6(1):36-43. doi: 10.1002/cpdd.288. Epub 2016 Sep 22. Clin Pharmacol Drug Dev. 2017. PMID: 27364900 Clinical Trial.
In both studies, the 2 formulations were bioequivalent to each other for the area under the plasma concentration-versus-time curve from time 0 to the last measurable concentration (AUCL), to infinity (AUC() ), and to 12 hours (AUC(0-12) ) and maximum concentration (C(max) ). In s …
In both studies, the 2 formulations were bioequivalent to each other for the area under the plasma concentration-versus-time curve from time …
Effect of preoperative ibuprofen in controlling postendodontic pain with and without low-level laser therapy in single visit endodontics: A randomized clinical study.
Nabi S, Amin K, Masoodi A, Farooq R, Purra AR, Ahangar FA. Nabi S, et al. Indian J Dent Res. 2018 Jan-Feb;29(1):46-50. doi: 10.4103/ijdr.IJDR_327_15. Indian J Dent Res. 2018. PMID: 29442086 Free article. Clinical Trial.
Group D (n = 30) patients were administered no preoperative ibuprofen nor low-level laser irradiation after the endodontic procedure. ...The combination of low-level laser and ibuprofen showed the best results in terms of postoperative pain reduction. ...
Group D (n = 30) patients were administered no preoperative ibuprofen nor low-level laser irradiation after the endodontic procedure. …
A multicenter, randomized, open-label, active-comparator trial to determine the efficacy, safety, and pharmacokinetics of intravenous ibuprofen for treatment of fever in hospitalized pediatric patients.
Khalil SN, Hahn BJ, Chumpitazi CE, Rock AD, Kaelin BA, Macias CG. Khalil SN, et al. BMC Pediatr. 2017 Feb 1;17(1):42. doi: 10.1186/s12887-017-0795-y. BMC Pediatr. 2017. PMID: 28143430 Free PMC article. Clinical Trial.
The main objectives of this randomized controlled study was to evaluate the efficacy and safety of single or multiple doses of intravenous ibuprofen to acetaminophen (oral or suppository) in pediatric patients with fever and to assess plasma ibuprofen concentrations …
The main objectives of this randomized controlled study was to evaluate the efficacy and safety of single or multiple doses of intravenous …
2,061 results