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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1967 1
1968 1
1969 2
1970 6
1971 3
1972 5
1973 16
1974 8
1975 14
1976 14
1977 14
1978 23
1979 31
1980 25
1981 16
1982 11
1983 29
1984 36
1985 30
1986 33
1987 30
1988 26
1989 27
1990 47
1991 43
1992 42
1993 33
1994 43
1995 42
1996 38
1997 44
1998 44
1999 40
2000 69
2001 45
2002 48
2003 49
2004 59
2005 49
2006 61
2007 58
2008 76
2009 64
2010 55
2011 69
2012 64
2013 67
2014 54
2015 53
2016 72
2017 94
2018 85
2019 78
2020 76
2021 90
2022 65
2023 44

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2,173 results

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Page 1
Ibuprofen versus paracetamol for treating fever in preschool children in Nigeria: a randomized clinical trial of effectiveness and safety.
Alaje EO, Udoh EE, Akande PA, Odey FA, Meremikwu MM. Alaje EO, et al. Pan Afr Med J. 2020 Aug 26;36:350. doi: 10.11604/pamj.2020.36.350.21393. eCollection 2020. Pan Afr Med J. 2020. PMID: 33224416 Free PMC article. Clinical Trial.
INTRODUCTION: fever is the primary symptom of most childhood illnesses and a cause of concern to their caregivers. The antipyretics commonly used to treat fever are ibuprofen and paracetamol. Most studies on the effectiveness of ibuprofen and paracetamol in treating …
INTRODUCTION: fever is the primary symptom of most childhood illnesses and a cause of concern to their caregivers. The antipyretics commonly …
Expectant Management or Early Ibuprofen for Patent Ductus Arteriosus.
Hundscheid T, Onland W, Kooi EMW, Vijlbrief DC, de Vries WB, Dijkman KP, van Kaam AH, Villamor E, Kroon AA, Visser R, Mulder-de Tollenaer SM, De Bisschop B, Dijk PH, Avino D, Hocq C, Zecic A, Meeus M, de Baat T, Derriks F, Henriksen TB, Kyng KJ, Donders R, Nuytemans DHGM, Van Overmeire B, Mulder AL, de Boode WP; BeNeDuctus Trial Investigators. Hundscheid T, et al. N Engl J Med. 2023 Mar 16;388(11):980-990. doi: 10.1056/NEJMoa2207418. Epub 2022 Dec 6. N Engl J Med. 2023. PMID: 36477458 Clinical Trial.
METHODS: In this multicenter, noninferiority trial, we randomly assigned infants with echocardiographically confirmed PDA (diameter, >1.5 mm, with left-to-right shunting) who were extremely preterm (<28 weeks' gestational age) to receive either expectant management or early …
METHODS: In this multicenter, noninferiority trial, we randomly assigned infants with echocardiographically confirmed PDA (diameter, >1.5 …
Pharmacokinetics and Bioavailability of a Fixed-Dose Combination of Ibuprofen and Paracetamol after Intravenous and Oral Administration.
Atkinson HC, Stanescu I, Frampton C, Salem II, Beasley CP, Robson R. Atkinson HC, et al. Clin Drug Investig. 2015 Oct;35(10):625-32. doi: 10.1007/s40261-015-0320-8. Clin Drug Investig. 2015. PMID: 26334726 Free PMC article. Clinical Trial.
Serial plasma samples were assayed for both paracetamol and ibuprofen concentrations, using validated liquid chromatography-tandem mass spectrometry methods. ...CONCLUSION: Concomitant administration of 3 mg/mL ibuprofen and 10 mg/mL paracetamol in a fixed-dose IV c …
Serial plasma samples were assayed for both paracetamol and ibuprofen concentrations, using validated liquid chromatography-tandem ma …
Paracetamol plus ibuprofen for the treatment of fever in children (PITCH): randomised controlled trial.
Hay AD, Costelloe C, Redmond NM, Montgomery AA, Fletcher M, Hollinghurst S, Peters TJ. Hay AD, et al. BMJ. 2008 Sep 2;337:a1302. doi: 10.1136/bmj.a1302. BMJ. 2008. PMID: 18765450 Free PMC article. Clinical Trial.
For less time with fever over 24 hours, paracetamol plus ibuprofen were superior to paracetamol (4.4 hours, 2.4 to 6.3; P<0.001) and to ibuprofen (2.5 hours, 0.6 to 4.4; P=0.008). ...CONCLUSION: Parents, nurses, pharmacists, and doctors wanting to use medicines t …
For less time with fever over 24 hours, paracetamol plus ibuprofen were superior to paracetamol (4.4 hours, 2.4 to 6.3; P<0.001) a …
Efficacy and safety of Curcuma domestica extracts compared with ibuprofen in patients with knee osteoarthritis: a multicenter study.
Kuptniratsaikul V, Dajpratham P, Taechaarpornkul W, Buntragulpoontawee M, Lukkanapichonchut P, Chootip C, Saengsuwan J, Tantayakom K, Laongpech S. Kuptniratsaikul V, et al. Clin Interv Aging. 2014 Mar 20;9:451-8. doi: 10.2147/CIA.S58535. eCollection 2014. Clin Interv Aging. 2014. PMID: 24672232 Free PMC article. Clinical Trial.
METHODS: 367 primary knee osteoarthritis patients with a pain score of 5 or higher were randomized to receive ibuprofen 1,200 mg/day or C. domestica extracts 1,500 mg/day for 4 weeks. ...However, the number of events of abdominal pain/discomfort was significantly higher in …
METHODS: 367 primary knee osteoarthritis patients with a pain score of 5 or higher were randomized to receive ibuprofen 1,200 mg/day …
Effects of ibuprofen administration timing on oral surgery pain: A randomized clinical trial.
La Monaca G, Pranno N, Annibali S, Polimeni A, Pompa G, Cristalli MP. La Monaca G, et al. Oral Dis. 2022 Apr;28(3):796-804. doi: 10.1111/odi.13781. Epub 2021 Feb 1. Oral Dis. 2022. PMID: 33486855 Clinical Trial.
OBJECTIVE: This study aimed to compare the analgesic effect of ibuprofen 400 mg given 30 min before or immediately after third molars surgery under local anaesthesia. ...Each patient was undergone to separate surgical sessions for the right and left side, and ibuprofen
OBJECTIVE: This study aimed to compare the analgesic effect of ibuprofen 400 mg given 30 min before or immediately after third molars …
Ibuprofen and Postpartum Blood Pressure in Women With Hypertensive Disorders of Pregnancy: A Randomized Controlled Trial.
Penfield CA, McNulty JA, Oakes MC, Nageotte MP. Penfield CA, et al. Obstet Gynecol. 2019 Dec;134(6):1219-1226. doi: 10.1097/AOG.0000000000003553. Obstet Gynecol. 2019. PMID: 31764732 Clinical Trial.
Postpartum average arterial pressure did not differ between study groups (938 mm Hg for those in the ibuprofen group vs 937 mm Hg in the control group, P=.93). Breakthrough opioid medications were requested by 24% of the participants in the ibuprofen group compared …
Postpartum average arterial pressure did not differ between study groups (938 mm Hg for those in the ibuprofen group vs 937 mm Hg in …
Single-Blind Randomized Controlled Trial: Comparative Efficacy of Dark Chocolate, Coconut Water, and Ibuprofen in Managing Primary Dysmenorrhea.
Nuha K, Rusmil K, Ganiem AR, Permadi W, Diah Herawati DM. Nuha K, et al. Int J Environ Res Public Health. 2023 Aug 21;20(16):6619. doi: 10.3390/ijerph20166619. Int J Environ Res Public Health. 2023. PMID: 37623203 Free PMC article. Clinical Trial.
Various pharmacological and non-pharmacological treatments are available for pain relief, but information on their effectiveness, particularly regarding green coconut water, dark chocolate, and Ibuprofen, remains limited. This study aimed to compare the effectiveness of gr …
Various pharmacological and non-pharmacological treatments are available for pain relief, but information on their effectiveness, particular …
Impact of ibuprofen and peroxisome proliferator-activated receptor gamma on emotion-related neural activation: A randomized, placebo-controlled trial.
Cosgrove KT, Kuplicki R, Savitz J, Burrows K, Simmons WK, Khalsa SS, Teague TK, Aupperle RL, Paulus MP. Cosgrove KT, et al. Brain Behav Immun. 2021 Aug;96:135-142. doi: 10.1016/j.bbi.2021.05.023. Epub 2021 May 27. Brain Behav Immun. 2021. PMID: 34052365 Free PMC article. Clinical Trial.
Nonsteroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen have shown initial promise in producing antidepressant effects. ...Thus, results suggest that ibuprofen and PPARgamma may have independent effects on emotional neurocircuitry. ...
Nonsteroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen have shown initial promise in producing antidepressant effects. ...Th …
Benefits and harm of paracetamol and ibuprofen in combination for post-operative pain: Pre-planned subgroup analyses of the multicenter, randomized PANSAID trial.
Thybo KH, Hägi-Pedersen D, Wetterslev J, Dahl JB, Jakobsen JC, Pedersen NA, Jakobsen K, Bülow HH, Ibsen L, Overgaard S, Mathiesen O. Thybo KH, et al. Acta Anaesthesiol Scand. 2020 Feb;64(2):245-253. doi: 10.1111/aas.13496. Epub 2019 Nov 16. Acta Anaesthesiol Scand. 2020. PMID: 31648374 Clinical Trial.
BACKGROUND: The "Paracetamol and Ibuprofen in Combination" (PANSAID) trial showed that combining paracetamol and ibuprofen resulted in lower opioid consumption than each drug alone and we did not find an increase in risk of harm when using ibuprofen vs parace …
BACKGROUND: The "Paracetamol and Ibuprofen in Combination" (PANSAID) trial showed that combining paracetamol and ibuprofen res …
2,173 results