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203 results

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Page 1
Alcohol-impregnated caps and ambulatory central-line-associated bloodstream infections (CLABSIs): A randomized clinical trial.
Milstone AM, Rosenberg C, Yenokyan G, Koontz DW, Miller MR; CCLIP Authorship Group. Milstone AM, et al. Infect Control Hosp Epidemiol. 2021 Apr;42(4):431-439. doi: 10.1017/ice.2020.467. Epub 2020 Oct 12. Infect Control Hosp Epidemiol. 2021. PMID: 33040755 Free PMC article. Clinical Trial.
INTERVENTION: Usual ambulatory central-line care per each institution using 70% isopropyl alcohol-impregnated caps at home compared to usual ambulatory central-line care in each institution without using 70% isopropyl alcohol-impregnated caps. ...Large …
INTERVENTION: Usual ambulatory central-line care per each institution using 70% isopropyl alcohol-impregnated caps at home com …
Skin Antisepsis before Surgical Fixation of Extremity Fractures.
PREP-IT Investigators; Sprague S, Slobogean G, Wells JL, O'Hara NN, Thabane L, Mullins CD, Harris AD, Wood A, Viskontas D, Apostle KL, O'Toole RV, Joshi M, Johal H, Al-Asiri J, Hymes RA, Gaski GE, Pilson HT, Carroll EA, Babcock S, Halvorson JJ, Romeo NM, Matson CA, Higgins TF, Marchand LS, Bergin PF, Morellato J, Van Demark RE 3rd, Potter GD, Gitajn IL, Chang G, Phelps KD, Kempton LB, Karunakar M, Jaeblon T, Demyanovich HK, Domes CM, Kuhn GR, Reilly RM, Gage MJ, Weaver MJ, von Keudell AG, Heng M, McTague MF, Alnasser A, Mehta S, Donegan DJ, Natoli RM, Szatkowski J, Scott AN, Shannon SF, Jeray KJ, Tanner SL, Marmor MT, Matityahu A, Fowler JT, Pierrie SN, Beltran MJ, Thomson CG, Lin CA, Moon CN, Scolaro JA, Amirhekmat A, Leonard J, Pogorzelski D, Bzovsky S, Heels-Ansdell D, Szasz OP, Gallant JL, Della Rocca GJ, Zura RD, Hebden JN, Patterson JT, Lee C, O'Hara LM, Marvel D, Palmer JE, Friedrich J, D'Alleyrand JG, Rivera JC, Mossuto F, Schrank GM, Guyatt G, Devereaux PJ, Bhandari M; The PREP-IT Investigators. PREP-IT Investigators, et al. N Engl J Med. 2024 Feb 1;390(5):409-420. doi: 10.1056/NEJMoa2307679. N Engl J Med. 2024. PMID: 38294973 Clinical Trial.
METHODS: In a cluster-randomized, crossover trial at 25 hospitals in the United States and Canada, we randomly assigned hospitals to use a solution of 0.7% iodine povacrylex in 74% isopropyl alcohol (iodine group) or 2% chlorhexidine gluconate in 70% isopropyl
METHODS: In a cluster-randomized, crossover trial at 25 hospitals in the United States and Canada, we randomly assigned hospitals to use a s …
Chlorhexidine-Alcohol versus Povidone-Iodine for Surgical-Site Antisepsis.
Darouiche RO, Wall MJ Jr, Itani KM, Otterson MF, Webb AL, Carrick MM, Miller HJ, Awad SS, Crosby CT, Mosier MC, Alsharif A, Berger DH. Darouiche RO, et al. N Engl J Med. 2010 Jan 7;362(1):18-26. doi: 10.1056/NEJMoa0810988. N Engl J Med. 2010. PMID: 20054046 Free article. Clinical Trial.
We hypothesized that preoperative skin cleansing with chlorhexidine-alcohol is more protective against infection than is povidone-iodine. METHODS: We randomly assigned adults undergoing clean-contaminated surgery in six hospitals to preoperative skin preparation with eithe …
We hypothesized that preoperative skin cleansing with chlorhexidine-alcohol is more protective against infection than is povidone-iod …
Use of alcohol containing caps for preventing bloodstream infections: A randomized controlled trial.
Taşdelen Öğülmen D, Ateş S. Taşdelen Öğülmen D, et al. J Vasc Access. 2021 Nov;22(6):920-925. doi: 10.1177/1129729820952961. Epub 2020 Aug 27. J Vasc Access. 2021. PMID: 32854563 Clinical Trial.
Isopropyl alcohol-containing caps were used for protecting the needle-free connectors closing the hubs of the central venous catheters in the intervention group. ...The risk of infection in the control group was 13.7 times higher than the risk of infection in the in
Isopropyl alcohol-containing caps were used for protecting the needle-free connectors closing the hubs of the central venous c
Skin antisepsis with chlorhexidine-alcohol versus povidone iodine-alcohol, with and without skin scrubbing, for prevention of intravascular-catheter-related infection (CLEAN): an open-label, multicentre, randomised, controlled, two-by-two factorial trial.
Mimoz O, Lucet JC, Kerforne T, Pascal J, Souweine B, Goudet V, Mercat A, Bouadma L, Lasocki S, Alfandari S, Friggeri A, Wallet F, Allou N, Ruckly S, Balayn D, Lepape A, Timsit JF; CLEAN trial investigators. Mimoz O, et al. Lancet. 2015 Nov 21;386(10008):2069-2077. doi: 10.1016/S0140-6736(15)00244-5. Epub 2015 Sep 18. Lancet. 2015. PMID: 26388532 Clinical Trial.
Before catheter insertion, we randomly assigned (1:1:1:1) patients via a secure web-based random-number generator (permuted blocks of eight, stratified by centre) to have all intravascular catheters prepared with 2% chlorhexidine-70% isopropyl alcohol (chlorhexidine …
Before catheter insertion, we randomly assigned (1:1:1:1) patients via a secure web-based random-number generator (permuted blocks of eight, …
Alcohol-based decontamination of gloved hands: A randomized controlled trial.
Thom KA, Rock C, Robinson GL, Reisinger HRS, Baloh J, Chasco E, Liang Y, Li S, Diekema DJ, Herwaldt LA, Johnson JK, Harris AD, Perencevich EN. Thom KA, et al. Infect Control Hosp Epidemiol. 2024 Apr;45(4):467-473. doi: 10.1017/ice.2023.243. Epub 2023 Nov 23. Infect Control Hosp Epidemiol. 2024. PMID: 37994538 Free PMC article. Clinical Trial.
OBJECTIVE: The gold standard for hand hygiene (HH) while wearing gloves requires removing gloves, performing HH, and donning new gloves between WHO moments. The novel strategy of applying alcohol-based hand rub (ABHR) directly to gloved hands might be effective and efficie …
OBJECTIVE: The gold standard for hand hygiene (HH) while wearing gloves requires removing gloves, performing HH, and donning new gloves betw …
A comparison of chlorhexidine and povidone-iodine solutions in neonatal intensive care units.
Kucuker H, Cakir SC, Koksal N, Ozkan H, Kocael F, Dorum BA, Sivrikaya Yildirim C, Celebi S, Hacimustafaoglu M. Kucuker H, et al. Pediatr Int. 2023 Jan-Dec;65(1):e15552. doi: 10.1111/ped.15552. Pediatr Int. 2023. PMID: 37350581 Clinical Trial.
BACKGROUND: Povidone-iodine (10%; PI) and 2% chlorhexidine in 70% isopropyl alcohol (CHG-IA) solutions are among the most widely used disinfectants in the neonatal intensive care units. ...
BACKGROUND: Povidone-iodine (10%; PI) and 2% chlorhexidine in 70% isopropyl alcohol (CHG-IA) solutions are among the most wide …
2% chlorhexidine gluconate aqueous versus 2% chlorhexidine gluconate in 70% isopropyl alcohol for skin disinfection prior to percutaneous central venous catheterisation: the ARCTIC randomised controlled feasibility trial.
Clarke P, Soe A, Nichols A, Harizaj H, Webber MA, Linsell L, Bell JL, Tremlett C, Muthukumar P, Pattnayak S, Partlett C, King A, Juszczak E, Heath PT. Clarke P, et al. Arch Dis Child Fetal Neonatal Ed. 2024 Feb 19;109(2):202-210. doi: 10.1136/archdischild-2023-325871. Arch Dis Child Fetal Neonatal Ed. 2024. PMID: 37907266 Free PMC article. Clinical Trial.
INTERVENTIONS: Skin disinfection with either 2% chlorhexidine gluconate (CHG)-aqueous or 2% CHG-70% isopropyl alcohol (IPA) before PCVC insertion and at removal. PRIMARY OUTCOME: Proportion in the 2% CHG-70% IPA arm with a colonised catheter at removal. ...
INTERVENTIONS: Skin disinfection with either 2% chlorhexidine gluconate (CHG)-aqueous or 2% CHG-70% isopropyl alcohol (IPA) be …
203 results