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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1961 5
1962 1
1963 8
1964 1
1966 4
1967 8
1968 6
1969 15
1970 22
1971 21
1972 19
1973 25
1974 29
1975 51
1976 56
1977 61
1978 72
1979 69
1980 85
1981 114
1982 94
1983 167
1984 130
1985 143
1986 123
1987 146
1988 124
1989 142
1990 130
1991 142
1992 154
1993 127
1994 137
1995 141
1996 92
1997 122
1998 104
1999 77
2000 95
2001 85
2002 90
2003 86
2004 83
2005 130
2006 105
2007 93
2008 71
2009 63
2010 56
2011 61
2012 49
2013 55
2014 50
2015 55
2016 45
2017 42
2018 35
2019 28
2020 29
2021 38
2022 1
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4,318 results
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Page 1
Isosorbide dinitrate.
Vaida A. Vaida A. Minn Med. 1983 Jan;66(1):41-2. Minn Med. 1983. PMID: 6843537 No abstract available.
Isosorbide dinitrate pharmacokinetics.
Taylor T, Chasseaud LF, Doyle E, Bonn R, Darragh A, Lambe RF. Taylor T, et al. Arzneimittelforschung. 1982;32(10):1329-33. Arzneimittelforschung. 1982. PMID: 6891236 No abstract available.
Pharmacokinetics of isosorbide dinitrate and isosorbide-5-mononitrate.
Schaumann W. Schaumann W. Int J Clin Pharmacol Ther Toxicol. 1989 Sep;27(9):445-53. Int J Clin Pharmacol Ther Toxicol. 1989. PMID: 2681004 Review.
Among many organic nitrates developed for this purpose, ISDN became the most prominent. ISDN is metabolized to isosorbide-2-mononitrate (IS-2-MN) and isosorbide-5-mononitrate (IS-5-MN) which are pharmacologically active. ...
Among many organic nitrates developed for this purpose, ISDN became the most prominent. ISDN is metabolized to isosorbide-2-mononitra …
Isosorbide-5-mononitrate and isosorbide dinitrate retard in the treatment of coronary heart disease: a multi-centre study.
Bidoggia H. Bidoggia H. Curr Med Res Opin. 1987;10(9):601-11. doi: 10.1185/03007998709112414. Curr Med Res Opin. 1987. PMID: 3325229 Clinical Trial.
A multi-centre study was carried out in 200 coronary patients to compare the efficacy and tolerance of isosorbide dinitrate retard (40 mg) and isosorbide-5-mononitrate (20 mg) with regard to the frequency of anginal attacks and consumption of sub-lingual (sho …
A multi-centre study was carried out in 200 coronary patients to compare the efficacy and tolerance of isosorbide dinitrate re …
Long-acting isosorbide mononitrate.
Prakash A, Markham A. Prakash A, et al. Drugs. 1999 Jan;57(1):93-9; discussion 100. doi: 10.2165/00003495-199957010-00008. Drugs. 1999. PMID: 9951954 Review.
The antianginal effects of once-daily isosorbide mononitrate EL 50 to 100mg were generally similar to those of conventional isosorbide mononitrate or isosorbide dinitrate 10 to 20mg twice or 3 times daily, or sustained-release nifedipine 20mg twice or …
The antianginal effects of once-daily isosorbide mononitrate EL 50 to 100mg were generally similar to those of conventional isosor
Metabolism of isosorbide dinitrate in the isolated perfused rabbit lung.
Mayer PR, Lubawy WC, McNamara PJ, Kostenbauder HB. Mayer PR, et al. J Pharm Sci. 1983 Jul;72(7):785-9. doi: 10.1002/jps.2600720717. J Pharm Sci. 1983. PMID: 6886987
Concentration versus time profiles from the isolated lung experiments indicate rapid metabolism of isosorbide dinitrate and corresponding increases in the metabolites 5-isosorbide mononitrate, 2-isosorbide mononitrate, and isosorbide. The data s …
Concentration versus time profiles from the isolated lung experiments indicate rapid metabolism of isosorbide dinitrate and co …
Absorption and excretion of isosorbide dinitrate and isosorbide-2-mononitrate in dogs.
Cayen MN, Hicks D, Karounis J, Dvornik D. Cayen MN, et al. J Pharm Pharmacol. 1983 May;35(5):312-6. doi: 10.1111/j.2042-7158.1983.tb02940.x. J Pharm Pharmacol. 1983. PMID: 6134800
In a crossover design four male dogs were given orally or i.v. [14C]isosorbide dinitrate (ISDN) or [14C]isosorbide-2-mononitrate (2-ISMN) at a dose of 1 mg kg-1 (70-80 microCi). ...The profile of serum radioactivity was similar after all drug administrations. …
In a crossover design four male dogs were given orally or i.v. [14C]isosorbide dinitrate (ISDN) or [14C]isosorbide-2-mo …
Comparative effects of nitroglycerin and isosorbide dinitrate on coronary collateral vessels and ischemic myocardium in dogs.
Cohen MV, Sonnenblick EH, Kirk ES. Cohen MV, et al. Am J Cardiol. 1976 Feb;37(2):244-9. doi: 10.1016/0002-9149(76)90319-2. Am J Cardiol. 1976. PMID: 813510 Review.
The contractile force was unchanged in the normal regions. Therefore, isosorbide dinitrate can dilate coronary collateral vessels and improve contractile force in ischemic areas. ...Although isosorbide dinitrate can directly dilate coronary collateral …
The contractile force was unchanged in the normal regions. Therefore, isosorbide dinitrate can dilate coronary collateral vess …
Duration of action of isosorbide dinitrate.
Russell RO Jr, Mantle JA, Rogers WJ, Rackley CE. Russell RO Jr, et al. Chest. 1979 Jan;75(1):2-4. doi: 10.1378/chest.75.1.2. Chest. 1979. PMID: 105835 Review. No abstract available.
Saliva concentrations of isosorbide dinitrate, isosorbide 2-mononitrate and isosorbide 5-mononitrate.
Taylor IW, Major RM, Chasseaud LF, Taylor T. Taylor IW, et al. Br J Clin Pharmacol. 1984 May;17(5):585-7. doi: 10.1111/j.1365-2125.1984.tb02394.x. Br J Clin Pharmacol. 1984. PMID: 6733004 Free PMC article.
Correlations between saliva and plasma concentrations of isosorbide dinitrate (ISDN), and its active metabolites, isosorbide 2-mononitrate (2-ISMN) and isosorbide 5-mononitrate (5-ISMN) were examined. ...
Correlations between saliva and plasma concentrations of isosorbide dinitrate (ISDN), and its active metabolites, isosorbid
4,318 results