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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1977 1
1980 1
1981 14
1982 4
1983 19
1984 14
1985 14
1986 14
1987 40
1988 27
1989 27
1990 28
1991 32
1992 30
1993 23
1994 29
1995 32
1996 14
1997 31
1998 22
1999 18
2000 34
2001 31
2002 28
2003 31
2004 18
2005 23
2006 28
2007 21
2008 20
2009 21
2010 20
2011 14
2012 17
2013 18
2014 9
2015 22
2016 8
2017 11
2018 11
2019 6
2020 10
2021 7
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820 results
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Page 1
Isosorbide Mononitrate in Heart Failure with Preserved Ejection Fraction.
Redfield MM, Anstrom KJ, Levine JA, Koepp GA, Borlaug BA, Chen HH, LeWinter MM, Joseph SM, Shah SJ, Semigran MJ, Felker GM, Cole RT, Reeves GR, Tedford RJ, Tang WH, McNulty SE, Velazquez EJ, Shah MR, Braunwald E; NHLBI Heart Failure Clinical Research Network. Redfield MM, et al. N Engl J Med. 2015 Dec 10;373(24):2314-24. doi: 10.1056/NEJMoa1510774. Epub 2015 Nov 8. N Engl J Med. 2015. PMID: 26549714 Free PMC article. Clinical Trial.
BACKGROUND: Nitrates are commonly prescribed to enhance activity tolerance in patients with heart failure and a preserved ejection fraction. We compared the effect of isosorbide mononitrate or placebo on daily activity in such patients. ...During all dose regimens, …
BACKGROUND: Nitrates are commonly prescribed to enhance activity tolerance in patients with heart failure and a preserved ejection fraction. …
Long-acting isosorbide mononitrate.
Prakash A, Markham A. Prakash A, et al. Drugs. 1999 Jan;57(1):93-9; discussion 100. doi: 10.2165/00003495-199957010-00008. Drugs. 1999. PMID: 9951954 Review.
The antianginal effects of once-daily isosorbide mononitrate EL 50 to 100mg were generally similar to those of conventional isosorbide mononitrate or isosorbide dinitrate 10 to 20mg twice or 3 times daily, or sustained-release nifedipine 20mg tw …
The antianginal effects of once-daily isosorbide mononitrate EL 50 to 100mg were generally similar to those of conventional …
Comparative analysis of cost-effectiveness between isosorbide-5-mononitrate and isosorbide: a retrospective real-world evaluation.
Zhang G, Liu X, Xu J, Cheng G, Xu J. Zhang G, et al. J Comp Eff Res. 2020 Apr;9(6):405-412. doi: 10.2217/cer-2019-0099. Epub 2020 Apr 17. J Comp Eff Res. 2020. PMID: 32301331
Aim: The cost-effectiveness of isosorbide-5-mononitrate (5-ISMN) and isosorbide dinitrate (ISDN) in real-world use in patients with coronary heart disease (CHD; either angina pectoris or myocardial infarction) was retrospectively compared …
Aim: The cost-effectiveness of isosorbide-5-mononitrate (5-ISMN) and isosorbide dinitrate (ISDN) in real- …
Intravaginal administration of isosorbide mononitrate for cervical ripening in prolonged pregnancy: a randomised clinical trial.
Mirteimouri M, Pourali L, Najaf Najafi M, Ghaffarian Omid M. Mirteimouri M, et al. J Obstet Gynaecol. 2020 Aug;40(6):792-796. doi: 10.1080/01443615.2019.1669546. Epub 2019 Dec 18. J Obstet Gynaecol. 2020. PMID: 31852287 Clinical Trial.
This study was performed to evaluate the efficacy of intravaginal isosorbide mononitrate (IMN) for cervical ripening in prolonged pregnancies. 122 pregnant women were recruited. ...According to results of the current study; using isosorbide mononitrate
This study was performed to evaluate the efficacy of intravaginal isosorbide mononitrate (IMN) for cervical ripening in prolon …
Pharmacokinetics of isosorbide mononitrate.
Abshagen UW. Abshagen UW. Am J Cardiol. 1992 Nov 27;70(17):61G-66G. doi: 10.1016/0002-9149(92)90028-w. Am J Cardiol. 1992. PMID: 1449102 Review.
Pharmacokinetic studies show that isosorbide mononitrate is rapidly absorbed after oral administration, reaches peak concentrations within an hour, undergoes no significant first-pass metabolism, and is virtually 100% bioavailable. ...Only 1-2% of an orally administ …
Pharmacokinetic studies show that isosorbide mononitrate is rapidly absorbed after oral administration, reaches peak concentra …
Meta-analysis: isosorbide-mononitrate alone or with either beta-blockers or endoscopic therapy for the management of oesophageal varices.
Gluud LL, Langholz E, Krag A. Gluud LL, et al. Aliment Pharmacol Ther. 2010 Oct;32(7):859-71. doi: 10.1111/j.1365-2036.2010.04418.x. Aliment Pharmacol Ther. 2010. PMID: 20839387 Free article. Review.
BACKGROUND: The evidence concerning the use of isosorbide-mononitrate (IsMn) for oesophageal varices is equivocal. ...The effect of IsMn plus beta-blockers on mortality in secondary prevention was not confirmed in trial sequential analysis. CONCLUSIONS: Is
BACKGROUND: The evidence concerning the use of isosorbide-mononitrate (IsMn) for oesophageal varices is equivocal. ...T …
Isosorbide mononitrate versus alendronate for postmenopausal osteoporosis.
Nabhan AF, Rabie NH. Nabhan AF, et al. Int J Gynaecol Obstet. 2008 Dec;103(3):213-6. doi: 10.1016/j.ijgo.2008.07.011. Epub 2008 Sep 21. Int J Gynaecol Obstet. 2008. PMID: 18805524 Clinical Trial.
OBJECTIVE: To compare the effectiveness, safety, and affordability of isosorbide mononitrate with alendronate for postmenopausal osteoporosis. ...A 10.8% and 12.1% change in BMD after 12 months was seen for isosorbide mononitrate and alendronate, respe …
OBJECTIVE: To compare the effectiveness, safety, and affordability of isosorbide mononitrate with alendronate for postmenopaus …
Isosorbide 5-mononitrate kinetics.
Major RM, Taylor T, Chasseaud LF, Darragh A, Lambe RF. Major RM, et al. Clin Pharmacol Ther. 1984 May;35(5):653-9. doi: 10.1038/clpt.1984.90. Clin Pharmacol Ther. 1984. PMID: 6713775
The kinetics of isosorbide 5-mononitrate (5-ISMN) were studied in 12 healthy subjects after intravenous infusion and oral doses of 20 mg. ...At the end of intravenous infusion of 5-ISMN at a rate of 8 mg/hr for 2.5 hr, mean plasma drug co …
The kinetics of isosorbide 5-mononitrate (5-ISMN) were studied in 12 healthy subjects after intravenous infusion …
Nitrates: why and how should they be used today? Current status of the clinical usefulness of nitroglycerin, isosorbide dinitrate and isosorbide-5-mononitrate.
Silber S. Silber S. Eur J Clin Pharmacol. 1990;38 Suppl 1:S35-51. doi: 10.1007/BF01417564. Eur J Clin Pharmacol. 1990. PMID: 2113003 Review.
Similarly, tolerance to isosorbide-5-mononitrate also does not develop when it is ingested once daily. ...The prolonged duration of action of once-daily high-dosage administration of sustained-release formulations, the improved patient compliance with a singl …
Similarly, tolerance to isosorbide-5-mononitrate also does not develop when it is ingested once daily. ...The prolonged …
820 results