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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1975 1
1976 1
1977 2
1979 1
1980 1
1981 23
1982 5
1983 29
1984 29
1985 24
1986 17
1987 55
1988 33
1989 40
1990 37
1991 42
1992 41
1993 29
1994 41
1995 44
1996 20
1997 38
1998 29
1999 28
2000 40
2001 37
2002 34
2003 39
2004 28
2005 29
2006 33
2007 26
2008 27
2009 27
2010 27
2011 18
2012 26
2013 24
2014 18
2015 30
2016 11
2017 18
2018 21
2019 18
2020 23
2021 18
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1,147 results
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Page 1
Isosorbide Mononitrate in Heart Failure with Preserved Ejection Fraction.
Redfield MM, Anstrom KJ, Levine JA, Koepp GA, Borlaug BA, Chen HH, LeWinter MM, Joseph SM, Shah SJ, Semigran MJ, Felker GM, Cole RT, Reeves GR, Tedford RJ, Tang WH, McNulty SE, Velazquez EJ, Shah MR, Braunwald E; NHLBI Heart Failure Clinical Research Network. Redfield MM, et al. N Engl J Med. 2015 Dec 10;373(24):2314-24. doi: 10.1056/NEJMoa1510774. Epub 2015 Nov 8. N Engl J Med. 2015. PMID: 26549714 Free PMC article. Clinical Trial.
BACKGROUND: Nitrates are commonly prescribed to enhance activity tolerance in patients with heart failure and a preserved ejection fraction. We compared the effect of isosorbide mononitrate or placebo on daily activity in such patients. ...During all dose regimens, …
BACKGROUND: Nitrates are commonly prescribed to enhance activity tolerance in patients with heart failure and a preserved ejection fraction. …
Comparative analysis of cost-effectiveness between isosorbide-5-mononitrate and isosorbide: a retrospective real-world evaluation.
Zhang G, Liu X, Xu J, Cheng G, Xu J. Zhang G, et al. J Comp Eff Res. 2020 Apr;9(6):405-412. doi: 10.2217/cer-2019-0099. Epub 2020 Apr 17. J Comp Eff Res. 2020. PMID: 32301331
Aim: The cost-effectiveness of isosorbide-5-mononitrate (5-ISMN) and isosorbide dinitrate (ISDN) in real-world use in patients with coronary heart disease (CHD; either angina pectoris or myocardial infarction) was retrospectively compared. ...Th …
Aim: The cost-effectiveness of isosorbide-5-mononitrate (5-ISMN) and isosorbide dinitrate (ISDN) in real- …
Long-acting isosorbide mononitrate.
Prakash A, Markham A. Prakash A, et al. Drugs. 1999 Jan;57(1):93-9; discussion 100. doi: 10.2165/00003495-199957010-00008. Drugs. 1999. PMID: 9951954 Review.
The antianginal effects of once-daily isosorbide mononitrate EL 50 to 100mg were generally similar to those of conventional isosorbide mononitrate or isosorbide dinitrate 10 to 20mg twice or 3 times daily, or sustained-release nifedipine 20mg tw …
The antianginal effects of once-daily isosorbide mononitrate EL 50 to 100mg were generally similar to those of conventional …
Intravaginal administration of isosorbide mononitrate for cervical ripening in prolonged pregnancy: a randomised clinical trial.
Mirteimouri M, Pourali L, Najaf Najafi M, Ghaffarian Omid M. Mirteimouri M, et al. J Obstet Gynaecol. 2020 Aug;40(6):792-796. doi: 10.1080/01443615.2019.1669546. Epub 2019 Dec 18. J Obstet Gynaecol. 2020. PMID: 31852287 Clinical Trial.
This study was performed to evaluate the efficacy of intravaginal isosorbide mononitrate (IMN) for cervical ripening in prolonged pregnancies. 122 pregnant women were recruited. ...According to results of the current study; using isosorbide mononitrate
This study was performed to evaluate the efficacy of intravaginal isosorbide mononitrate (IMN) for cervical ripening in prolon …
Isosorbide 5-mononitrate pharmacokinetics.
Chasseaud LF. Chasseaud LF. Cardiology. 1987;74 Suppl 1:6-11. doi: 10.1159/000174255. Cardiology. 1987. PMID: 3300979 Review.
Isosorbide 5-mononitrate differs from other clinically used organic nitrate vasodilators because of its almost complete oral absorption, the low intersubject variability in its plasma concentrations and pharmacokinetic parameters, its relatively long half-lif
Isosorbide 5-mononitrate differs from other clinically used organic nitrate vasodilators because of its almost complete
Pharmacokinetics of isosorbide mononitrate.
Abshagen UW. Abshagen UW. Am J Cardiol. 1992 Nov 27;70(17):61G-66G. doi: 10.1016/0002-9149(92)90028-w. Am J Cardiol. 1992. PMID: 1449102 Review.
Pharmacokinetic studies show that isosorbide mononitrate is rapidly absorbed after oral administration, reaches peak concentrations within an hour, undergoes no significant first-pass metabolism, and is virtually 100% bioavailable. ...Only 1-2% of an orally administ …
Pharmacokinetic studies show that isosorbide mononitrate is rapidly absorbed after oral administration, reaches peak concentra …
Effects of isosorbide-5-mononitrate and isosorbide-2-mononitrate on the contractile and electrical activity and on the content of cyclic nucleotides in isolated heart muscles of the guinea-pig and dog.
Atanassova R, Spassov G, Balansky R, Boev K. Atanassova R, et al. J Pharm Pharmacol. 1992 Aug;44(8):663-6. doi: 10.1111/j.2042-7158.1992.tb05490.x. J Pharm Pharmacol. 1992. PMID: 1359091
Isosorbide-5-mononitrate and isosorbide-2-mononitrate, the metabolites of isosorbide dinitrate, were studied for their effects on the contractile and electrical activity and on the content of cyclic nucleotides in isolated heart muscles o
Isosorbide-5-mononitrate and isosorbide-2-mononitrate, the metabolites of isosorbide dinitrate, we
Meta-analysis: isosorbide-mononitrate alone or with either beta-blockers or endoscopic therapy for the management of oesophageal varices.
Gluud LL, Langholz E, Krag A. Gluud LL, et al. Aliment Pharmacol Ther. 2010 Oct;32(7):859-71. doi: 10.1111/j.1365-2036.2010.04418.x. Aliment Pharmacol Ther. 2010. PMID: 20839387 Free article. Review.
BACKGROUND: The evidence concerning the use of isosorbide-mononitrate (IsMn) for oesophageal varices is equivocal. ...The effect of IsMn plus beta-blockers on mortality in secondary prevention was not confirmed in trial sequential analysis. CONCLUSIONS: Isosorbid
BACKGROUND: The evidence concerning the use of isosorbide-mononitrate (IsMn) for oesophageal varices is equivocal. ...The effe …
Pharmacokinetics of isosorbide dinitrate and isosorbide-5-mononitrate.
Schaumann W. Schaumann W. Int J Clin Pharmacol Ther Toxicol. 1989 Sep;27(9):445-53. Int J Clin Pharmacol Ther Toxicol. 1989. PMID: 2681004 Review.
Among many organic nitrates developed for this purpose, ISDN became the most prominent. ISDN is metabolized to isosorbide-2-mononitrate (IS-2-MN) and isosorbide-5-mononitrate (IS-5-MN) which are pharmacologically active. ...After oral adm …
Among many organic nitrates developed for this purpose, ISDN became the most prominent. ISDN is metabolized to isosorbide-2-mononi
1,147 results