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Year Number of Results
1980 3
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1982 14
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1987 10
1988 9
1989 6
1990 7
1991 4
1992 14
1993 10
1994 19
1995 18
1996 13
1997 18
1998 18
1999 20
2000 15
2001 16
2002 18
2003 16
2004 15
2005 16
2006 20
2007 10
2008 13
2009 22
2010 15
2011 19
2012 13
2013 18
2014 19
2015 14
2016 10
2017 14
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2023 11
2024 8
2025 6

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554 results

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Page 1
Efficacy of Carboplatin and Isotretinoin in Children With High-risk Medulloblastoma: A Randomized Clinical Trial From the Children's Oncology Group.
Leary SES, Packer RJ, Li Y, Billups CA, Smith KS, Jaju A, Heier L, Burger P, Walsh K, Han Y, Embry L, Hadley J, Kumar R, Michalski J, Hwang E, Gajjar A, Pollack IF, Fouladi M, Northcott PA, Olson JM. Leary SES, et al. JAMA Oncol. 2021 Sep 1;7(9):1313-1321. doi: 10.1001/jamaoncol.2021.2224. JAMA Oncol. 2021. PMID: 34292305 Free PMC article. Clinical Trial.
OBJECTIVE: To evaluate therapy intensification with carboplatin as a radiosensitizer and isotretinoin as a proapoptotic agent in children with high-risk medulloblastoma in a randomized clinical trial and, with a correlative biology study, facilitate planned subgroup analys …
OBJECTIVE: To evaluate therapy intensification with carboplatin as a radiosensitizer and isotretinoin as a proapoptotic agent in chil …
Anti-GD2 antibody with GM-CSF, interleukin-2, and isotretinoin for neuroblastoma.
Yu AL, Gilman AL, Ozkaynak MF, London WB, Kreissman SG, Chen HX, Smith M, Anderson B, Villablanca JG, Matthay KK, Shimada H, Grupp SA, Seeger R, Reynolds CP, Buxton A, Reisfeld RA, Gillies SD, Cohn SL, Maris JM, Sondel PM; Children's Oncology Group. Yu AL, et al. N Engl J Med. 2010 Sep 30;363(14):1324-34. doi: 10.1056/NEJMoa0911123. N Engl J Med. 2010. PMID: 20879881 Free PMC article. Clinical Trial.
We conducted a study to determine whether adding ch14.18, GM-CSF, and interleukin-2 to standard isotretinoin therapy after intensive multimodal therapy would improve outcomes in high-risk neuroblastoma. METHODS: Patients with high-risk neuroblastoma who had a response to i …
We conducted a study to determine whether adding ch14.18, GM-CSF, and interleukin-2 to standard isotretinoin therapy after intensive …
Long-Term Follow-up of a Phase III Study of ch14.18 (Dinutuximab) + Cytokine Immunotherapy in Children with High-Risk Neuroblastoma: COG Study ANBL0032.
Yu AL, Gilman AL, Ozkaynak MF, Naranjo A, Diccianni MB, Gan J, Hank JA, Batova A, London WB, Tenney SC, Smith M, Shulkin BL, Parisi M, Matthay KK, Cohn SL, Maris JM, Bagatell R, Park JR, Sondel PM. Yu AL, et al. Clin Cancer Res. 2021 Apr 15;27(8):2179-2189. doi: 10.1158/1078-0432.CCR-20-3909. Epub 2021 Jan 27. Clin Cancer Res. 2021. PMID: 33504555 Free PMC article. Clinical Trial.
PATIENTS AND METHODS: Patients recieved six cycles of isotretinoin with or without five cycles of immunotherapy which consists of dinutuximab with GM-CSF alternating with IL2. ...RESULTS: For 226 eligible randomized patients, 5-year EFS was 56.6 4.7% for patients randomize …
PATIENTS AND METHODS: Patients recieved six cycles of isotretinoin with or without five cycles of immunotherapy which consists of din …
Effect of antihistamine as an adjuvant treatment of isotretinoin in acne: a randomized, controlled comparative study.
Lee HE, Chang IK, Lee Y, Kim CD, Seo YJ, Lee JH, Im M. Lee HE, et al. J Eur Acad Dermatol Venereol. 2014 Dec;28(12):1654-60. doi: 10.1111/jdv.12403. Epub 2014 Feb 21. J Eur Acad Dermatol Venereol. 2014. PMID: 25081735 Clinical Trial.
BACKGROUND: Isotretinoin has been frequently used for acne therapy. However, it has limitation in acceptance because of its adverse effects. ...RESULTS: At week 12, compared with isotretinoin only group, isotretinoin with additional antihistamine group showed …
BACKGROUND: Isotretinoin has been frequently used for acne therapy. However, it has limitation in acceptance because of its adverse e …
Interleukin 2 with anti-GD2 antibody ch14.18/CHO (dinutuximab beta) in patients with high-risk neuroblastoma (HR-NBL1/SIOPEN): a multicentre, randomised, phase 3 trial.
Ladenstein R, Pötschger U, Valteau-Couanet D, Luksch R, Castel V, Yaniv I, Laureys G, Brock P, Michon JM, Owens C, Trahair T, Chan GCF, Ruud E, Schroeder H, Beck Popovic M, Schreier G, Loibner H, Ambros P, Holmes K, Castellani MR, Gaze MN, Garaventa A, Pearson ADJ, Lode HN. Ladenstein R, et al. Lancet Oncol. 2018 Dec;19(12):1617-1629. doi: 10.1016/S1470-2045(18)30578-3. Epub 2018 Nov 12. Lancet Oncol. 2018. PMID: 30442501 Clinical Trial.
In this component of the trial, patients were randomly assigned (1:1) to receive dinutuximab beta (20 mg/m(2) per day as an 8 h infusion for 5 consecutive days) or dinutuximab beta plus subcutaneous IL-2 (6 10(6) IU/m(2) per day on days 1-5 and days 8-12 of each cycle) with the m …
In this component of the trial, patients were randomly assigned (1:1) to receive dinutuximab beta (20 mg/m(2) per day as an 8 h infusion for …
Treatment of Resistant Acne Vulgaris in Adolescents Using Dietary Supplementation with Magnesium, Phosphate and Fatty Acids (Omega 6 and 7): Comparison with 13-Cis-Retinoic Acid.
de Souza Pereira R. de Souza Pereira R. J Diet Suppl. 2023;20(5):706-716. doi: 10.1080/19390211.2022.2100550. Epub 2022 Jul 25. J Diet Suppl. 2023. PMID: 35876008 Clinical Trial.
A single-blind randomized study was conducted in which 257 patients were treated with the above dietary supplementation (group A) and 275 patients with isotretinoin (group B) for 6 months. All patients in group A (100%) reported complete regression of symptoms after 6 mont …
A single-blind randomized study was conducted in which 257 patients were treated with the above dietary supplementation (group A) and 275 pa …
Levels of several inflammatory cytokines in acne patients before and after isotretinoin therapy: a randomized, controlled clinical trial.
Qi W, Wang R, Khasawneh SMS, Hui F, Liu Y. Qi W, et al. J Dermatolog Treat. 2025 Dec;36(1):2540594. doi: 10.1080/09546634.2025.2540594. Epub 2025 Jul 31. J Dermatolog Treat. 2025. PMID: 40739900 Free article. Clinical Trial.

IL-8, IL-36, and TWEAK levels were found to be significantly decreased after 8 weeks of isotretinoin treatment (p < 0.05). There was no correlation found between the severity of acne and inflammatory cytokine levels (p > 0.05). CONCLUSION: The anti-inflammatory effec

…

IL-8, IL-36, and TWEAK levels were found to be significantly decreased after 8 weeks of isotretinoin treatment (p < 0.05). There w

…
Effect of oral doxycycline, azithromycin and isotretinoin on haematological inflammatory markers and interleukin-17A levels in acne vulgaris: a single blinded randomised interventional study.
Agrawal A, Bhardwaj A, Singh S, Budania A, Bains A, Sharma S, Purohit A, Rajan M B, Rajagopal V. Agrawal A, et al. Arch Dermatol Res. 2024 Oct 17;316(10):697. doi: 10.1007/s00403-024-03434-x. Arch Dermatol Res. 2024. PMID: 39417892 Clinical Trial.
Amidst the existing literature on the effect of isotretinoin on serum interleukin-17 levels in acne patients, the effects of oral antibiotics azithromycin and doxycycline on serum interleukin-17 is scarce. ...Baseline Global acne grading scale (GAGS) in doxycycline, azithr …
Amidst the existing literature on the effect of isotretinoin on serum interleukin-17 levels in acne patients, the effects of oral ant …
Efficacy and safety of combined oral isotretinoin and desloratadine vs. isotretinoin alone in acne vulgaris: a comparative study.
El-Ghareeb MI, Kandeel AH, Khayrullah NM. El-Ghareeb MI, et al. Arch Dermatol Res. 2025 Apr 10;317(1):689. doi: 10.1007/s00403-025-04145-7. Arch Dermatol Res. 2025. PMID: 40204949 Clinical Trial.
A combination of desloratadine (DESL) and oral isotretinoin (ISO) may enhance efficacy and reduce the side effects of ISO, particularly those affecting the skin and mucous membranes. ...
A combination of desloratadine (DESL) and oral isotretinoin (ISO) may enhance efficacy and reduce the side effects of ISO, particular …
Chemoprevention of cancer.
van Zandwijk N, Pastorino U, de Vries N. van Zandwijk N, et al. Eur Respir J. 1993 Mar;6(3):322-4. Eur Respir J. 1993. PMID: 8472818 Clinical Trial. No abstract available.
554 results