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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1948 1
1949 6
1950 10
1951 39
1952 31
1953 26
1954 18
1955 15
1956 10
1957 15
1958 7
1959 9
1960 15
1961 13
1962 10
1963 23
1964 30
1965 24
1966 15
1967 18
1968 25
1969 19
1970 24
1971 42
1972 30
1973 42
1974 27
1975 61
1976 54
1977 93
1978 81
1979 69
1980 66
1981 92
1982 103
1983 69
1984 82
1985 83
1986 91
1987 116
1988 140
1989 141
1990 180
1991 203
1992 242
1993 280
1994 236
1995 292
1996 265
1997 264
1998 263
1999 281
2000 283
2001 297
2002 324
2003 351
2004 384
2005 407
2006 375
2007 381
2008 421
2009 439
2010 482
2011 502
2012 529
2013 512
2014 524
2015 477
2016 436
2017 415
2018 467
2019 526
2020 585
2021 544
2022 437
2023 378
2024 441
2025 516
2026 249

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14,896 results

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Page 1
Leucovorin (folinic acid) rescue for high-dose methotrexate: A review.
Jiang R, Mei S, Zhao Z. Jiang R, et al. J Clin Pharm Ther. 2022 Sep;47(9):1452-1460. doi: 10.1111/jcpt.13739. Epub 2022 Aug 5. J Clin Pharm Ther. 2022. PMID: 35929573 Review.
There are many strategies to overcome HDMTX-induced toxicities, such as hydration, alkalization, leucovorin rescue, and haemodialysis. Leucovorin rescue is a cornerstone for toxicity prevention in HDMTX treatment. However, the leucovorin dose adjustment and t …
There are many strategies to overcome HDMTX-induced toxicities, such as hydration, alkalization, leucovorin rescue, and haemodialysis …
Cerebral folate receptor autoantibodies in autism spectrum disorder.
Frye RE, Sequeira JM, Quadros EV, James SJ, Rossignol DA. Frye RE, et al. Mol Psychiatry. 2013 Mar;18(3):369-81. doi: 10.1038/mp.2011.175. Epub 2012 Jan 10. Mol Psychiatry. 2013. PMID: 22230883 Free PMC article. Clinical Trial.
Autism spectrum disorders (ASDs) and improvements in ASD symptoms with leucovorin (folinic acid) treatment have been reported in some children with CFD. In children with ASD, the prevalence of FRAs and the response to leucovorin in FRA-positive children has not been …
Autism spectrum disorders (ASDs) and improvements in ASD symptoms with leucovorin (folinic acid) treatment have been reported in some …
Clinical concerns and considerations for leucovorin use in autism spectrum disorder.
Howard C, Mekhail J, Ravikoff LM, Milanaik R. Howard C, et al. Curr Opin Pediatr. 2026 Apr 1;38(2):207-211. doi: 10.1097/MOP.0000000000001547. Epub 2026 Feb 2. Curr Opin Pediatr. 2026. PMID: 41670435 Review.
Certain studies have indicated reductions in communication deficits in nonverbal children with ASD, particularly those with these autoantibodies, following consistent leucovorin use. However, other studies have found no change in symptoms despite leucovorin intake. …
Certain studies have indicated reductions in communication deficits in nonverbal children with ASD, particularly those with these autoantibo …
Autism initiative embraces little-tested vitamin as a treatment.
Vogel G. Vogel G. Science. 2025 Sep 25;389(6767):1282-1283. doi: 10.1126/science.aec5468. Epub 2025 Sep 25. Science. 2025. PMID: 40997185
FDA to approve leucovorin despite questions about whom it might help....
FDA to approve leucovorin despite questions about whom it might help....
Leucovorin.
Betcher DL, Burnham N. Betcher DL, et al. J Pediatr Oncol Nurs. 1989 Jul;6(3):102-4. J Pediatr Oncol Nurs. 1989. PMID: 2604922 No abstract available.
Vincristine overdose.
Barna P. Barna P. Clin Pediatr (Phila). 1980 Jun;19(6):440. doi: 10.1177/000992288001900614. Clin Pediatr (Phila). 1980. PMID: 6966208 No abstract available.
Anything in modulation?
Gray R, Hills R, Stowe R. Gray R, et al. Ann Oncol. 2003 Sep;14(9):1338-9. doi: 10.1093/annonc/mdg381. Ann Oncol. 2003. PMID: 12954571 Free article. No abstract available.
The pharmacology of methotrexate.
Olsen EA. Olsen EA. J Am Acad Dermatol. 1991 Aug;25(2 Pt 1):306-18. doi: 10.1016/0190-9622(91)70199-c. J Am Acad Dermatol. 1991. PMID: 1918470 Review.
With the appropriate knowledge of the importance of urinary excretion of methotrexate and factors that influence this and with the ready availability of leucovorin, toxicity can be avoided in all but the most unusual of circumstances....
With the appropriate knowledge of the importance of urinary excretion of methotrexate and factors that influence this and with the ready ava …
Leucovorin rescue revisited.
Bertino JR. Bertino JR. J Clin Oncol. 1990 Feb;8(2):193-5. doi: 10.1200/JCO.1990.8.2.193. J Clin Oncol. 1990. PMID: 2299365 No abstract available.
Leucovorin-induced hypersensitivity reaction.
Damaske A, Ma N, Williams R. Damaske A, et al. J Oncol Pharm Pract. 2012 Mar;18(1):136-9. doi: 10.1177/1078155210396577. Epub 2011 Jan 19. J Oncol Pharm Pract. 2012. PMID: 21248170
We describe a 53-year-old male, who was started on FOLFOX 6 + bevacizumab who experienced a hypersensitivity reaction to leucovorin. There have been very few cases of leucovorin hypersensitivity reactions reported in the literature. In this case, symptoms include fl …
We describe a 53-year-old male, who was started on FOLFOX 6 + bevacizumab who experienced a hypersensitivity reaction to leucovorin. …
14,896 results
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