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Page 1
Levetiracetam.
Howard P, Remi J, Remi C, Charlesworth S, Whalley H, Bhatia R, Hitchens M, Mihalyo M, Wilcock A. Howard P, et al. J Pain Symptom Manage. 2018 Oct;56(4):645-649. doi: 10.1016/j.jpainsymman.2018.07.012. Epub 2018 Jul 21. J Pain Symptom Manage. 2018. PMID: 30036676 Free article. Review.
Levetiracetam for Seizure Prophylaxis in Neurocritical Care: A Systematic Review and Meta-analysis.
Fang T, Valdes E, Frontera JA. Fang T, et al. Neurocrit Care. 2022 Feb;36(1):248-258. doi: 10.1007/s12028-021-01296-z. Epub 2021 Jul 20. Neurocrit Care. 2022. PMID: 34286461
The coprimary meta-analyses examined first seizure events in (1) levetiracetam versus no antiseizure medication and (2) levetiracetam versus other antiseizure medications in all ICH, TBI, SAH, and supratentorial neurosurgery populations. ...Levetiracetam may …
The coprimary meta-analyses examined first seizure events in (1) levetiracetam versus no antiseizure medication and (2) levetirace …
Initial Management of Seizure in Adults.
Smith PEM. Smith PEM. N Engl J Med. 2021 Jul 15;385(3):251-263. doi: 10.1056/NEJMcp2024526. N Engl J Med. 2021. PMID: 34260837 Review. No abstract available.
Behavioral adverse events with brivaracetam, levetiracetam, perampanel, and topiramate: A systematic review.
Steinhoff BJ, Klein P, Klitgaard H, Laloyaux C, Moseley BD, Ricchetti-Masterson K, Rosenow F, Sirven JI, Smith B, Stern JM, Toledo M, Zipfel PA, Villanueva V. Steinhoff BJ, et al. Epilepsy Behav. 2021 May;118:107939. doi: 10.1016/j.yebeh.2021.107939. Epub 2021 Apr 8. Epilepsy Behav. 2021. PMID: 33839453 Free article. Review.
PURPOSE: To understand the currently available post-marketing real-world evidence of the incidences of and discontinuations due to the BAEs of irritability, anger, and aggression in people with epilepsy (PWE) treated with the anti-seizure medications (ASMs) brivaracetam (BRV), …
PURPOSE: To understand the currently available post-marketing real-world evidence of the incidences of and discontinuations due to the BAEs …
Levetiracetam vs Lamotrigine as First-Line Antiseizure Medication in Female Patients With Idiopathic Generalized Epilepsy.
Cerulli Irelli E, Cocchi E, Morano A, Gesche J, Caraballo RH, Lattanzi S, Strigaro G, Catania C, Ferlazzo E, Pascarella A, Casciato S, Quarato P, Pizzanelli C, Pulitano P, Giuliano L, Viola V, Mostacci B, Fortunato F, Marini C, Di Gennaro G, Gambardella A, Labate A, Operto FF, Giallonardo AT, Baykan B, Beier CP, Di Bonaventura C; Women With Epilepsy Treatment Options and Research (WETOR) Study Group. Cerulli Irelli E, et al. JAMA Neurol. 2023 Nov 1;80(11):1174-1181. doi: 10.1001/jamaneurol.2023.3400. JAMA Neurol. 2023. PMID: 37782485 Free PMC article.
OBJECTIVE: To compare the effectiveness and safety of levetiracetam and lamotrigine as initial monotherapy in female patients of childbearing age with IGE. ...EXPOSURES: Levetiracetam or lamotrigine as initial monotherapy. MAIN OUTCOMES AND MEASURES: Inverse probabi …
OBJECTIVE: To compare the effectiveness and safety of levetiracetam and lamotrigine as initial monotherapy in female patients of chil …
Status epilepticus in pregnancy: a literature review and a protocol proposal.
Roberti R, Rocca M, Iannone LF, Gasparini S, Pascarella A, Neri S, Cianci V, Bilo L, Russo E, Quaresima P, Aguglia U, Di Carlo C, Ferlazzo E. Roberti R, et al. Expert Rev Neurother. 2022 Apr;22(4):301-312. doi: 10.1080/14737175.2022.2057224. Epub 2022 Apr 7. Expert Rev Neurother. 2022. PMID: 35317697 Review.
Benzodiazepines are the drugs of choice for SE in pregnancy. Levetiracetam and phenytoin represent the most suitable second-line agents. Valproic acid should be administered only if other ASMs failed and preferably avoided in the first trimester of pregnancy. ...
Benzodiazepines are the drugs of choice for SE in pregnancy. Levetiracetam and phenytoin represent the most suitable second-line agen …
Update on the management of status epilepticus.
Rossetti AO, Alvarez V. Rossetti AO, et al. Curr Opin Neurol. 2021 Apr 1;34(2):172-181. doi: 10.1097/WCO.0000000000000899. Curr Opin Neurol. 2021. PMID: 33664203 Review.
The recently published ESETT trial provides high-level evidence regarding the equivalence of fosphenytoin, valproate, and levetiracetam as a second-line option. Myoclonus or epileptiform transients on electroencephalography occur in up to 1/3 of patients surviving a cardia …
The recently published ESETT trial provides high-level evidence regarding the equivalence of fosphenytoin, valproate, and levetiracetam …
Status epilepticus: review on diagnosis, monitoring and treatment.
Pinto LF, Oliveira JPS, Midon AM. Pinto LF, et al. Arq Neuropsiquiatr. 2022 May;80(5 Suppl 1):193-203. doi: 10.1590/0004-282X-ANP-2022-S113. Arq Neuropsiquiatr. 2022. PMID: 35976303 Free PMC article.
Benzodiazepines are the initial treatment, and should be given fast and an adequate dose. Phenytoin/fosphenytoin, levetiracetam and valproic acid are evidence choices for second line treatment. If SE persists, anesthetic drugs are probably the best option for third line tr …
Benzodiazepines are the initial treatment, and should be given fast and an adequate dose. Phenytoin/fosphenytoin, levetiracetam and v …
Levetiracetam.
Alrabiah H. Alrabiah H. Profiles Drug Subst Excip Relat Methodol. 2019;44:167-204. doi: 10.1016/bs.podrm.2019.02.003. Epub 2019 Mar 25. Profiles Drug Subst Excip Relat Methodol. 2019. PMID: 31029217
A comprehensive profile of levetiracetam is presented in this chapter which includes its description, formula, elemental analysis, appearance, uses and applications. ...
A comprehensive profile of levetiracetam is presented in this chapter which includes its description, formula, elemental analysis, ap …
The SANAD II study of the effectiveness and cost-effectiveness of valproate versus levetiracetam for newly diagnosed generalised and unclassifiable epilepsy: an open-label, non-inferiority, multicentre, phase 4, randomised controlled trial.
Marson A, Burnside G, Appleton R, Smith D, Leach JP, Sills G, Tudur-Smith C, Plumpton C, Hughes DA, Williamson P, Baker GA, Balabanova S, Taylor C, Brown R, Hindley D, Howell S, Maguire M, Mohanraj R, Smith PE; SANAD II collaborators. Marson A, et al. Lancet. 2021 Apr 10;397(10282):1375-1386. doi: 10.1016/S0140-6736(21)00246-4. Lancet. 2021. PMID: 33838758 Free PMC article. Clinical Trial.
For participants aged 12 years or older, the initial advised maintenance doses were 500 mg twice per day for levetiracetam and valproate, and for children aged 5-12 years, the initial daily maintenance doses advised were 25 mg/kg for valproate and 40 mg/kg for levetirac …
For participants aged 12 years or older, the initial advised maintenance doses were 500 mg twice per day for levetiracetam and valpro …
5,928 results