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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1971 5
1972 7
1973 20
1974 14
1975 13
1976 22
1977 19
1978 16
1979 13
1980 17
1981 13
1982 20
1983 34
1984 28
1985 28
1986 26
1987 22
1988 34
1989 31
1990 25
1991 30
1992 26
1993 29
1994 30
1995 32
1996 27
1997 29
1998 33
1999 23
2000 31
2001 22
2002 27
2003 28
2004 39
2005 29
2006 26
2007 30
2008 19
2009 19
2010 19
2011 21
2012 23
2013 23
2014 23
2015 13
2016 11
2017 12
2018 12
2019 11
2020 12
2021 13
2022 1
2023 5
2024 8
2025 8
2026 1

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1,086 results

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Page 1
Comparison of the actions of diazepam and lorazepam.
Dundee JW, McGowan WA, Lilburn JK, McKay AC, Hegarty JE. Dundee JW, et al. Br J Anaesth. 1979 May;51(5):439-46. doi: 10.1093/bja/51.5.439. Br J Anaesth. 1979. PMID: 36117 Free article. Clinical Trial.
Diazepam and lorazepam differ in potency and in the time-course of their action. As a sedative, diazepam 10 mg is equivalent to lorazepam 2-2.5 mg. ...Lorazepam i.v. is followed by a lesser frequency of venous thrombosis....
Diazepam and lorazepam differ in potency and in the time-course of their action. As a sedative, diazepam 10 mg is equivalent to lo …
Effect of Lorazepam With Haloperidol vs Haloperidol Alone on Agitated Delirium in Patients With Advanced Cancer Receiving Palliative Care: A Randomized Clinical Trial.
Hui D, Frisbee-Hume S, Wilson A, Dibaj SS, Nguyen T, De La Cruz M, Walker P, Zhukovsky DS, Delgado-Guay M, Vidal M, Epner D, Reddy A, Tanco K, Williams J, Hall S, Liu D, Hess K, Amin S, Breitbart W, Bruera E. Hui D, et al. JAMA. 2017 Sep 19;318(11):1047-1056. doi: 10.1001/jama.2017.11468. JAMA. 2017. PMID: 28975307 Free PMC article. Clinical Trial.
The lorazepam + haloperidol group required less median rescue neuroleptics (2.0 mg) than the placebo + haloperidol group (4.0 mg) (median difference, -1.0 mg [95% CI, -2.0 to 0]; P = .009) and was perceived to be more comfortable by both blinded caregivers and nurses (care …
The lorazepam + haloperidol group required less median rescue neuroleptics (2.0 mg) than the placebo + haloperidol group (4.0 mg) (me …
Proportional Sedation for Persistent Agitated Delirium in Palliative Care: A Randomized Clinical Trial.
Hui D, De La Rosa A, Tsai JS, Cheng SY, Del Fabbro E, Thomas Kuzhiyil AT, Rowe K, Azhar A, Nguyen T, Tang M, Yao CA, Huang HL, Peng JK, Hu WY, Admane S, Dev R, Chen M, Bramati P, Shete S, Bruera E. Hui D, et al. JAMA Oncol. 2025 Sep 1;11(9):1031-1043. doi: 10.1001/jamaoncol.2025.2212. JAMA Oncol. 2025. PMID: 40742738 Clinical Trial.
OBJECTIVE: To compare the effect of scheduled haloperidol, lorazepam, haloperidol plus lorazepam, and placebo on patients with advanced cancer and delirium and experiencing restlessness and/or agitation in the palliative care setting. ...INTERVENTIONS: Scheduled int …
OBJECTIVE: To compare the effect of scheduled haloperidol, lorazepam, haloperidol plus lorazepam, and placebo on patients with …
Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial.
Pandharipande PP, Pun BT, Herr DL, Maze M, Girard TD, Miller RR, Shintani AK, Thompson JL, Jackson JC, Deppen SA, Stiles RA, Dittus RS, Bernard GR, Ely EW. Pandharipande PP, et al. JAMA. 2007 Dec 12;298(22):2644-53. doi: 10.1001/jama.298.22.2644. JAMA. 2007. PMID: 18073360 Clinical Trial.

RESULTS: Sedation with dexmedetomidine resulted in more days alive without delirium or coma (median days, 7.0 vs 3.0; P = .01) and a lower prevalence of coma (63% vs 92%; P < .001) than sedation with lorazepam. Patients sedated with dexmedetomidine spent more time withi

…
RESULTS: Sedation with dexmedetomidine resulted in more days alive without delirium or coma (median days, 7.0 vs 3.0; P = .01) and a lower p …
Efficacy of ketamine for initial control of acute agitation in the emergency department: A randomized study.
Lin J, Figuerado Y, Montgomery A, Lee J, Cannis M, Norton VC, Calvo R, Sikand H. Lin J, et al. Am J Emerg Med. 2021 Jun;44:306-311. doi: 10.1016/j.ajem.2020.04.013. Epub 2020 Apr 11. Am J Emerg Med. 2021. PMID: 32340820 Clinical Trial.
Adult patients with combative agitation were randomized to ketamine (4 mg/kg IM or 1 mg/kg IV) or haloperidol/lorazepam (haloperidol 5-10 mg IM or IV + lorazepam 1-2 mg IM or IV). The primary outcome was sedation within 5 min, and secondary outcomes included sedatio …
Adult patients with combative agitation were randomized to ketamine (4 mg/kg IM or 1 mg/kg IV) or haloperidol/lorazepam (haloperidol …
Intranasal Dexmedetomidine for the Management of Preoperative Anxiety-Related Insomnia: A Randomized, Three-Blinded, Clinical Trial Compared with Lorazepam and Placebo.
Yang WY, Huang K, Lin ZJ, Zeng W, Liu X, Liu HB, Zhong ML, Wei J, Liang WD, Wang LF, Chen L. Yang WY, et al. Drug Des Devel Ther. 2024 Dec 17;18:6061-6073. doi: 10.2147/DDDT.S487463. eCollection 2024. Drug Des Devel Ther. 2024. PMID: 39717197 Free PMC article. Clinical Trial.
PURPOSE: To evaluate the efficacy and safety of intranasal dexmedetomidine (Dex), oral lorazepam, and a placebo in managing preoperative anxiety-related insomnia. PATIENTS AND METHODS: A total of 90 patients exhibiting symptoms of preoperative anxiety and insomnia were ran …
PURPOSE: To evaluate the efficacy and safety of intranasal dexmedetomidine (Dex), oral lorazepam, and a placebo in managing preoperat …
Lorazepam vs diazepam for pediatric status epilepticus: a randomized clinical trial.
Chamberlain JM, Okada P, Holsti M, Mahajan P, Brown KM, Vance C, Gonzalez V, Lichenstein R, Stanley R, Brousseau DC, Grubenhoff J, Zemek R, Johnson DW, Clemons TE, Baren J; Pediatric Emergency Care Applied Research Network (PECARN). Chamberlain JM, et al. JAMA. 2014 Apr 23-30;311(16):1652-60. doi: 10.1001/jama.2014.2625. JAMA. 2014. PMID: 24756515 Clinical Trial.
IMPORTANCE: Benzodiazepines are considered first-line therapy for pediatric status epilepticus. Some studies suggest that lorazepam may be more effective or safer than diazepam, but lorazepam is not Food and Drug Administration approved for this indication. ...There …
IMPORTANCE: Benzodiazepines are considered first-line therapy for pediatric status epilepticus. Some studies suggest that lorazepam m …
Comparative trial of intravenous lorazepam and clonazepam im status epilepticus.
Sorel L, Mechler L, Harmant J. Sorel L, et al. Clin Ther. 1981;4(4):326-36. Clin Ther. 1981. PMID: 6120763 Clinical Trial.
The primary use of lorazepam, when administered intravenously (IV), has been in the treatment of acute attacks of anxiety and agitation. ...The present study compared the efficacy and tolerability of lorazepam and clonazepam in the treatment of status epilepticus. …
The primary use of lorazepam, when administered intravenously (IV), has been in the treatment of acute attacks of anxiety and agitati …
Antipsychotic drug-induced dysphoria.
Lynch G, Green JF, King DJ. Lynch G, et al. Br J Psychiatry. 1996 Oct;169(4):524. doi: 10.1192/bjp.169.4.524b. Br J Psychiatry. 1996. PMID: 8894211 Clinical Trial. No abstract available.
1,086 results