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Page 1
Structure and function of the human mitochondrial MRS2 channel.
He Z, Tu YC, Tsai CW, Mount J, Zhang J, Tsai MF, Yuan P. He Z, et al. Nat Struct Mol Biol. 2025 Mar;32(3):459-468. doi: 10.1038/s41594-024-01420-5. Epub 2024 Nov 28. Nat Struct Mol Biol. 2025. PMID: 39609651 Free PMC article.
Moreover, a conserved arginine ring within the pore of MRS2 functions to restrict cation movements, thus preventing the channel from collapsing the proton motive force that drives mitochondrial adenosine triphosphate synthesis. ...
Moreover, a conserved arginine ring within the pore of MRS2 functions to restrict cation movements, thus preventing the channel from …
Selectivity mechanism of magnesium and calcium in cation-binding pocket structures of phosphotyrosine.
Tu Y, Liu H, Shi G, Zhang F, Su T, Wu Y, Sun J, Zhang L, Zhang S, Fang H. Tu Y, et al. Phys Rev E. 2020 Feb;101(2-1):022410. doi: 10.1103/PhysRevE.101.022410. Phys Rev E. 2020. PMID: 32168574
Magnesium (Mg^{2+}) and calcium (Ca^{2+}) are of essential importance in biological activity, but the molecular understanding of their selectivity is still lacking. ...The key for the selectivity is attributed to the cation-pi interactions between the hydrated catio …
Magnesium (Mg^{2+}) and calcium (Ca^{2+}) are of essential importance in biological activity, but the molecular understanding of thei …
1,3-Diphosphacyclobutene Cobalt Complexes.
Rödl C, Schwedtmann K, Weigand JJ, Wolf R. Rödl C, et al. Chemistry. 2019 Apr 26;25(24):6180-6188. doi: 10.1002/chem.201900170. Epub 2019 Apr 8. Chemistry. 2019. PMID: 30840328
In contrast to the reactions with PhLi, the aryl-magnesium compounds p-tolyl magnesium chloride and p-fluorophenyl magnesium bromide deprotonate [Co(P(2) C(2) tBu(2) )(2) H] to give the magnesium salt [Mg(MeCN)(6) ][Co(eta(4) -P(2) C(2) tBu(2) )(2) ](2 …
In contrast to the reactions with PhLi, the aryl-magnesium compounds p-tolyl magnesium chloride and p-fluorophenyl magnesiu …
Structural basis of elongation factor 2 switching.
Fenwick MK, Ealick SE. Fenwick MK, et al. Curr Res Struct Biol. 2020 Feb 28;2:25-34. doi: 10.1016/j.crstbi.2020.02.001. eCollection 2020. Curr Res Struct Biol. 2020. PMID: 34235467 Free PMC article.
Here, we describe crystal structures of Methanoperedens nitroreducens EF-2 (MnEF-2) and MnEF-2-H595N bound to GMPPCP (GppCp) and magnesium displaying previously unreported compact conformations. Domain III forms interfaces with the other four domains and the overall confor …
Here, we describe crystal structures of Methanoperedens nitroreducens EF-2 (MnEF-2) and MnEF-2-H595N bound to GMPPCP (GppCp) and magnesiu …
Excitatory glycine receptors containing the NR3 family of NMDA receptor subunits.
Chatterton JE, Awobuluyi M, Premkumar LS, Takahashi H, Talantova M, Shin Y, Cui J, Tu S, Sevarino KA, Nakanishi N, Tong G, Lipton SA, Zhang D. Chatterton JE, et al. Nature. 2002 Feb 14;415(6873):793-8. doi: 10.1038/nature715. Epub 2002 Jan 30. Nature. 2002. PMID: 11823786
Moreover, NR1/NR3A or -3B receptors form relatively Ca2+-impermeable cation channels that are resistant to Mg2+, MK-801, memantine and competitive antagonists. ...
Moreover, NR1/NR3A or -3B receptors form relatively Ca2+-impermeable cation channels that are resistant to Mg2+, MK-801, memantine an …
The role of hydrated divalent metal ions in the bridging of two anionic groups. An ab initio quantum chemical and molecular mechanics study of dimethyl phosphate and formate bridged by calcium and magnesium ions.
Deerfield DW 2nd, Lapadat MA, Spremulli LL, Hiskey RG, Pedersen LG. Deerfield DW 2nd, et al. J Biomol Struct Dyn. 1989 Jun;6(6):1077-91. doi: 10.1080/07391102.1989.10506538. J Biomol Struct Dyn. 1989. PMID: 2818858
Ab initio quantum chemical (Gaussian82) and molecular mechanics (AMBER2.0) computational techniques are employed to investigate the interaction of two anions (formate an dimethylphosphate) and a central divalent metal cation (magnesium or calcium). These systems are …
Ab initio quantum chemical (Gaussian82) and molecular mechanics (AMBER2.0) computational techniques are employed to investigate the interact …
Calcyclin mediates serum response element (SRE) activation by an osteoblastic extracellular cation-sensing mechanism.
Tu Q, Pi M, Quarles LD. Tu Q, et al. J Bone Miner Res. 2003 Oct;18(10):1825-33. doi: 10.1359/jbmr.2003.18.10.1825. J Bone Miner Res. 2003. PMID: 14584893 Free article.
METHODS: To identify molecules that participate in this extracellular cation-sensing pathway, we developed an expression cloning strategy in COS-7 cells using cation stimulation of a serum response element (SRE) luciferase reporter derived from the c-fos promoter to …
METHODS: To identify molecules that participate in this extracellular cation-sensing pathway, we developed an expression cloning stra …
Crystal structures of hydrates of simple inorganic salts. I. Water-rich magnesium halide hydrates MgCl2.8H2O, MgCl2.12H2O, MgBr2.6H2O, MgBr2.9H2O, MgI2.8H2O and MgI2.9H2O.
Hennings E, Schmidt H, Voigt W. Hennings E, et al. Acta Crystallogr C. 2013 Nov;69(Pt 11):1292-300. doi: 10.1107/S0108270113028138. Epub 2013 Oct 31. Acta Crystallogr C. 2013. PMID: 24192174
Reported herein are the structures of a set of magnesium salts. Crystals of MgCl2.8H2O (magnesium dichloride octahydrate), MgCl2.12H2O (magnesium dichloride dodecahydrate), MgBr2.6H2O (magnesium dibromide hexahydrate), MgBr2.9H2O (magnesium dibr …
Reported herein are the structures of a set of magnesium salts. Crystals of MgCl2.8H2O (magnesium dichloride octahydrate), MgC …
Effects of arsenic on concentration and distribution of nutrients in the fronds of the arsenic hyperaccumulator Pteris vittata L.
Tu C, Ma LQ. Tu C, et al. Environ Pollut. 2005 May;135(2):333-40. doi: 10.1016/j.envpol.2004.03.026. Environ Pollut. 2005. PMID: 15734593
The frond P/As molar ratios of 1.0 can be used as the threshold value for normal growth of P. vittata. Potassium may function as a counter-cation for As in the fronds as shown by the As-induced K increases in the fronds. The present findings not only demonstrate that P. vi …
The frond P/As molar ratios of 1.0 can be used as the threshold value for normal growth of P. vittata. Potassium may function as a counter- …
Synthesis and structure of tetra-aqua-bis-(dimethyl ether)magnesium(II) dibromide dimethyl ether disolvate.
Moritz B, Mairath T, Strohmann C. Moritz B, et al. Acta Crystallogr E Crystallogr Commun. 2026 Apr 14;82(Pt 5):463-466. doi: 10.1107/S205698902600366X. eCollection 2026 May 1. Acta Crystallogr E Crystallogr Commun. 2026. PMID: 42099414 Free PMC article.
Unlike typical hexa-hydrates, the title compound, [Mg(C(2)H(6)O)(2)(H(2)O)(4)]Br(2).2C(2)H(6)O or [Mg(H(2)O)(4)(DME)(2)]Br(2).DME(2) (DME = dimethyl ether, C(2)H(6)O), is a water-poor magnesium(II) complex. The central magnesium cation (site symmetry 1) is co …
Unlike typical hexa-hydrates, the title compound, [Mg(C(2)H(6)O)(2)(H(2)O)(4)]Br(2).2C(2)H(6)O or [Mg(H(2)O)(4)(DME)(2)]Br(2).DME(2) (DME = …
12 results