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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1965 4
1966 2
1968 3
1969 3
1970 4
1971 1
1972 3
1973 5
1974 6
1975 6
1976 2
1977 4
1978 6
1979 10
1980 8
1981 11
1982 7
1983 10
1984 3
1985 9
1986 6
1987 11
1988 7
1989 8
1990 13
1991 12
1992 16
1993 26
1994 22
1995 21
1996 26
1997 24
1998 20
1999 26
2000 31
2001 35
2002 27
2003 26
2004 19
2005 32
2006 29
2007 29
2008 39
2009 27
2010 39
2011 39
2012 43
2013 52
2014 42
2015 38
2016 30
2017 36
2018 25
2019 27
2020 37
2021 24
2022 0
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982 results
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Page 1
Randomized Clinical Trial of 20% Mannitol Versus 3% Hypertonic Saline in Children With Raised Intracranial Pressure Due to Acute CNS Infections.
Rameshkumar R, Bansal A, Singhi S, Singhi P, Jayashree M. Rameshkumar R, et al. Pediatr Crit Care Med. 2020 Dec;21(12):1071-1080. doi: 10.1097/PCC.0000000000002557. Pediatr Crit Care Med. 2020. PMID: 33003179 Clinical Trial.
OBJECTIVES: Mannitol is a commonly used osmotherapy agent in raised intracranial pressure. However, the side effects of mannitol are significant. In traumatic brain injury (adult and pediatric), hypertonic saline (3%) shows varied results in comparison with 20% m
OBJECTIVES: Mannitol is a commonly used osmotherapy agent in raised intracranial pressure. However, the side effects of mannitol
Relationship between Symptoms, Exacerbations, and Treatment Response in Bronchiectasis.
Gao YH, Abo Leyah H, Finch S, Lonergan M, Aliberti S, De Soyza A, Fardon TC, Tino G, Chalmers JD. Gao YH, et al. Am J Respir Crit Care Med. 2020 Jun 15;201(12):1499-1507. doi: 10.1164/rccm.201910-1972OC. Am J Respir Crit Care Med. 2020. PMID: 32097051 Free article. Clinical Trial.
Patients with higher symptom scores had higher exacerbation rates (RR, 1.74; 95% CI, 1.12-2.72; P = 0.01) over 12-month follow-up than those with lower symptoms. Inhaled mannitol treatment improved the time to first exacerbation (hazard ratio, 0.56; 95% CI, 0.40-0.77; P &l …
Patients with higher symptom scores had higher exacerbation rates (RR, 1.74; 95% CI, 1.12-2.72; P = 0.01) over 12-month follow-up than those …
Equimolar doses of hypertonic agents (saline or mannitol) in the treatment of intracranial hypertension after severe traumatic brain injury.
Huang X, Yang L, Ye J, He S, Wang B. Huang X, et al. Medicine (Baltimore). 2020 Sep 18;99(38):e22004. doi: 10.1097/MD.0000000000022004. Medicine (Baltimore). 2020. PMID: 32957318 Free PMC article. Clinical Trial.
BACKGROUND: Mannitol and hypertonic saline (HTS) are effective in reducing intracranial pressure (ICP) after severe traumatic brain injury (TBI). ...The proportion of efficacious doses of HTS on ICP reduction may be higher than mannitol....
BACKGROUND: Mannitol and hypertonic saline (HTS) are effective in reducing intracranial pressure (ICP) after severe traumatic brain i …
A Comparative Study of Bolus Dose of Hypertonic Saline, Mannitol, and Mannitol Plus Glycerol Combination in Patients with Severe Traumatic Brain Injury.
Patil H, Gupta R. Patil H, et al. World Neurosurg. 2019 May;125:e221-e228. doi: 10.1016/j.wneu.2019.01.051. Epub 2019 Jan 24. World Neurosurg. 2019. PMID: 30684710 Clinical Trial.
The mean dose required to reduce ICP below 15 mm Hg for 3% hypertonic saline: 1.4 mL/kg, for 10% mannitol plus 10% glycerine: 1.7 mL/kg, and for 20% mannitol: 2.0 mL/kg. The mean time required to reduce ICP below 15 mm Hg for 3% hypertonic saline: 16 minutes, for 10 …
The mean dose required to reduce ICP below 15 mm Hg for 3% hypertonic saline: 1.4 mL/kg, for 10% mannitol plus 10% glycerine: 1.7 mL/ …
Comparison of 3% Hypertonic Saline and 20% Mannitol for Reducing Intracranial Pressure in Patients Undergoing Supratentorial Brain Tumor Surgery: A Randomized, Double-blind Clinical Trial.
Ali A, Tetik A, Sabanci PA, Altun D, Sivrikoz N, Abdullah T, Aydoseli A, Sencer A, Akinci IO. Ali A, et al. J Neurosurg Anesthesiol. 2018 Apr;30(2):171-178. doi: 10.1097/ANA.0000000000000446. J Neurosurg Anesthesiol. 2018. PMID: 28763434 Clinical Trial.
BACKGROUND: In the present study, we hypothesized that 3% hypertonic saline (HS) is more effective than 20% mannitol to reduce intracranial pressure (ICP) and to modify brain bulk in patients undergoing an elective supratentorial craniotomy. ...CONCLUSIONS: Our results sug …
BACKGROUND: In the present study, we hypothesized that 3% hypertonic saline (HS) is more effective than 20% mannitol to reduce intrac …
Mannitol and renal graft injury in patients undergoing deceased donor renal transplantation - a randomized controlled clinical trial.
Reiterer C, Hu K, Sljivic S, Falkner von Sonnenburg M, Fleischmann E, Kainz A, Kabon B. Reiterer C, et al. BMC Nephrol. 2020 Jul 28;21(1):307. doi: 10.1186/s12882-020-01961-z. BMC Nephrol. 2020. PMID: 32723374 Free PMC article. Clinical Trial.
We evaluated the effect of mannitol to reduce renal graft injury represented by 16 serum biomarkers, which are indicators for different important pathophysiological pathways. ...Thus, we do not support the routinely use of mannitol to attenuate I/R injury. TRIAL REG …
We evaluated the effect of mannitol to reduce renal graft injury represented by 16 serum biomarkers, which are indicators for differe …
Acute renal failure.
Mann HJ, Fuhs DW, Hemstrom CA. Mann HJ, et al. Drug Intell Clin Pharm. 1986 Jun;20(6):421-38. doi: 10.1177/106002808602000602. Drug Intell Clin Pharm. 1986. PMID: 3087724 Review.
Studies examining the prevention and treatment of ARF in animal models and trials in humans are evaluated. Mannitol 0.5-1 g/kg, furosemide 0.5-1 mg/kg initially, and dopamine 1-5 micrograms/kg/min are effective in preventing or decreasing the severity of ARF in animal mode …
Studies examining the prevention and treatment of ARF in animal models and trials in humans are evaluated. Mannitol 0.5-1 g/kg, furos …
Mannitol and dopamine in patients undergoing cardiopulmonary bypass: a randomized clinical trial.
Carcoana OV, Mathew JP, Davis E, Byrne DW, Hayslett JP, Hines RL, Garwood S. Carcoana OV, et al. Anesth Analg. 2003 Nov;97(5):1222-1229. doi: 10.1213/01.ANE.0000086727.42573.A8. Anesth Analg. 2003. PMID: 14570627 Clinical Trial.
One-hundred patients with a preoperative serum creatinine level mannitol 1 g/kg added to the CPB prime, 3). dopamine 2 microg kg(-1x. min(-1) from the induction of anesthesia to 1 h post-CPB, or …
One-hundred patients with a preoperative serum creatinine level
The effect of deep inhalation on mannitol responsiveness.
Blais CM, Davis BE, Cockcroft DW. Blais CM, et al. Clin Exp Allergy. 2020 Mar;50(3):308-314. doi: 10.1111/cea.13543. Epub 2019 Dec 14. Clin Exp Allergy. 2020. PMID: 31785175 Clinical Trial.
Only the inhalation technique for dose administration differed between repeat mannitol or methacholine challenges. RESULTS: Deep inhalations did not significantly influence the provocative dose of mannitol causing a 15% fall in forced expiratory volume in 1 second ( …
Only the inhalation technique for dose administration differed between repeat mannitol or methacholine challenges. RESULTS: Deep inha …
Effect of mannitol on postreperfusion cardiac output and central venous oxygen saturation during orthotopic liver transplant: a double-blind randomized clinical trial.
Sahmeddini MA, Zahiri S, Khosravi MB, Ghaffaripour S, Eghbal MH, Shokrizadeh S. Sahmeddini MA, et al. Prog Transplant. 2014 Jun;24(2):121-5. doi: 10.7182/pit2014483. Prog Transplant. 2014. PMID: 24919727 Clinical Trial.
Oxygen-derived free radicals play an important role in the genesis of postreperfusion syndrome, but the effect of mannitol (a free radical scavenger) on attenuating the syndrome is unclear.OBJECTIVES-To investigate the effectiveness of infusing mannitol during the a …
Oxygen-derived free radicals play an important role in the genesis of postreperfusion syndrome, but the effect of mannitol (a free ra …
982 results