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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1958 1
1959 1
1960 2
1963 1
1964 2
1965 1
1966 1
1967 8
1968 4
1970 3
1971 4
1972 2
1973 5
1974 4
1975 3
1976 2
1977 6
1978 4
1979 8
1980 8
1981 5
1982 2
1983 3
1984 8
1985 6
1986 11
1987 13
1988 10
1989 14
1990 6
1991 16
1992 5
1993 13
1994 6
1995 8
1996 6
1997 8
1998 8
1999 5
2000 12
2001 6
2002 8
2003 11
2004 19
2005 17
2006 15
2007 9
2008 12
2009 16
2010 11
2011 12
2012 11
2013 15
2014 13
2015 18
2016 21
2017 7
2018 17
2019 13
2020 15
2021 10
2022 13
2023 10
2024 1

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493 results

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Page 1
Structure and mechanism of carbonic anhydrase.
Lindskog S. Lindskog S. Pharmacol Ther. 1997;74(1):1-20. doi: 10.1016/s0163-7258(96)00198-2. Pharmacol Ther. 1997. PMID: 9336012 Review.
The enzyme is the target for drugs, such as acetazolamide, methazolamide, and dichlorphenamide, for the treatment of glaucoma. There are three evolutionarily unrelated CA families, designated alpha, beta, and gamma. ...
The enzyme is the target for drugs, such as acetazolamide, methazolamide, and dichlorphenamide, for the treatment of glaucoma. There …
Methazolamide.
[No authors listed] [No authors listed] 2021 Sep 20. Drugs and Lactation Database (LactMed®) [Internet]. Bethesda (MD): National Institute of Child Health and Human Development; 2006–. 2021 Sep 20. Drugs and Lactation Database (LactMed®) [Internet]. Bethesda (MD): National Institute of Child Health and Human Development; 2006–. PMID: 30000740 Free Books & Documents. Review.
No information is available on the use of methazolamide during breastfeeding. The American, Canadian and French professional guidelines consider carbonic anhydrase inhibitors acceptable in breastfeeding.[1,2] However, an alternate drug with more published information may b …
No information is available on the use of methazolamide during breastfeeding. The American, Canadian and French professional guidelin …
Imatinib and methazolamide ameliorate COVID-19-induced metabolic complications via elevating ACE2 enzymatic activity and inhibiting viral entry.
Li Z, Peng M, Chen P, Liu C, Hu A, Zhang Y, Peng J, Liu J, Li Y, Li W, Zhu W, Guan D, Zhang Y, Chen H, Li J, Fan D, Huang K, Lin F, Zhang Z, Guo Z, Luo H, He X, Zhu Y, Li L, Huang B, Cai W, Gu L, Lu Y, Deng K, Yan L, Chen S. Li Z, et al. Cell Metab. 2022 Mar 1;34(3):424-440.e7. doi: 10.1016/j.cmet.2022.01.008. Epub 2022 Feb 11. Cell Metab. 2022. PMID: 35150639 Free PMC article.
Imatinib and methazolamide remarkably improve metabolic perturbations in vivo in an ACE2-dependent manner under the insulin-resistant state and SARS-CoV-2-infected state. ...Taken together, our study shows that enzymatic activation of ACE2 via imatinib, methazolamide
Imatinib and methazolamide remarkably improve metabolic perturbations in vivo in an ACE2-dependent manner under the insulin-resistant …
Methazolamide in high-altitude illnesses.
Lu H, Zhang H, Jiang Y. Lu H, et al. Eur J Pharm Sci. 2020 May 30;148:105326. doi: 10.1016/j.ejps.2020.105326. Epub 2020 Apr 3. Eur J Pharm Sci. 2020. PMID: 32251722 Review.
Besides, methazolamide causes less fatigue side effects than acetazolamide does. ...Given methazolamide's advantages over acetazolamide, methazolamide may thus represent an alternative for acetazolamide when taken for high-altitude illnesses prophylaxis and t …
Besides, methazolamide causes less fatigue side effects than acetazolamide does. ...Given methazolamide's advantages over acet …
Diuretics.
[No authors listed] [No authors listed] 2021 Oct 13. LiverTox: Clinical and Research Information on Drug-Induced Liver Injury [Internet]. Bethesda (MD): National Institute of Diabetes and Digestive and Kidney Diseases; 2012–. 2021 Oct 13. LiverTox: Clinical and Research Information on Drug-Induced Liver Injury [Internet]. Bethesda (MD): National Institute of Diabetes and Digestive and Kidney Diseases; 2012–. PMID: 31644115 Free Books & Documents. Review.
The carbonic anhydrase blockers acetazolamide (1986) and methazolamide (1959) are also diuretics, but are more commonly used for the therapy of glaucoma. ...
The carbonic anhydrase blockers acetazolamide (1986) and methazolamide (1959) are also diuretics, but are more commonly used for the …
Carbonic Anhydrase Inhibitors.
[No authors listed] [No authors listed] 2021 Oct 13. LiverTox: Clinical and Research Information on Drug-Induced Liver Injury [Internet]. Bethesda (MD): National Institute of Diabetes and Digestive and Kidney Diseases; 2012–. 2021 Oct 13. LiverTox: Clinical and Research Information on Drug-Induced Liver Injury [Internet]. Bethesda (MD): National Institute of Diabetes and Digestive and Kidney Diseases; 2012–. PMID: 31643975 Free Books & Documents. Review.
Acetazolamide and methazolamide are carbonic anhydrase inhibitors used as diuretics and in the therapy of glaucoma. Both acetazolamide and methazolamide have been linked to rare cases of clinically apparent drug induced liver disease....
Acetazolamide and methazolamide are carbonic anhydrase inhibitors used as diuretics and in the therapy of glaucoma. Both acetazolamid …
Therapeutic Efficacy of Methazolamide Against Intermittent Hypoxia-Induced Excessive Erythrocytosis in Rats.
Zhang Z, Xiao Z, Deng B, Liu X, Liu W, Nie H, Li X, Chen Z, Yang D, Duan R. Zhang Z, et al. High Alt Med Biol. 2018 Mar;19(1):69-80. doi: 10.1089/ham.2017.0044. Epub 2017 Oct 27. High Alt Med Biol. 2018. PMID: 29077517
Methazolamide dose-dependently reduced the hemoglobin concentration, hematocrit (Hct), and blood viscosity. Hct/blood viscosity, an oxygen delivery index, dose-dependently increased after methazolamide treatment. A methazolamide dose of 10 mg.kg(-1).d(-1) sho
Methazolamide dose-dependently reduced the hemoglobin concentration, hematocrit (Hct), and blood viscosity. Hct/blood viscosity, an o
Revealing mechanism of Methazolamide for treatment of ankylosing spondylitis based on network pharmacology and GSEA.
Sun T, Wang M, Liang W, Gao P, Liu Q, Yan X. Sun T, et al. Sci Rep. 2023 Sep 16;13(1):15370. doi: 10.1038/s41598-023-42721-x. Sci Rep. 2023. PMID: 37717047 Free PMC article.
Methazolamide is a carbonic anhydrase (CA) inhibitor with satisfactory safety. Our previous studies have demonstrated the elevation of CA1 expression and the therapeutic effect of Methazolamide in Ankylosing spondylitis (AS). In this study, we explored the pathogeni
Methazolamide is a carbonic anhydrase (CA) inhibitor with satisfactory safety. Our previous studies have demonstrated the elevation o
Methazolamide Plus Aminophylline Abrogates Hypoxia-Mediated Endurance Exercise Impairment.
Scalzo RL, Binns SE, Klochak AL, Giordano GR, Paris HL, Sevits KJ, Beals JW, Biela LM, Larson DG, Luckasen GJ, Irwin D, Schroeder T, Hamilton KL, Bell C. Scalzo RL, et al. High Alt Med Biol. 2015 Dec;16(4):331-42. doi: 10.1089/ham.2015.0066. High Alt Med Biol. 2015. PMID: 26680684 Clinical Trial.
Fifteen healthy males (26 5 years, body-mass index: 24.9 1.6 kg/m(2); mean SD) were randomly assigned to one of four treatments: placebo (n = 9), methazolamide (250 mg; n = 10), aminophylline (400 mg; n = 9), or methazolamide (250 mg) with aminophylline (400 mg; n = …
Fifteen healthy males (26 5 years, body-mass index: 24.9 1.6 kg/m(2); mean SD) were randomly assigned to one of four treatments: placebo (n …
The Impact of Acetazolamide and Methazolamide on Exercise Performance in Normoxia and Hypoxia.
Doherty CJ, Chang JC, Thompson BP, Swenson ER, Foster GE, Dominelli PB. Doherty CJ, et al. High Alt Med Biol. 2023 Mar;24(1):7-18. doi: 10.1089/ham.2022.0134. Epub 2023 Feb 20. High Alt Med Biol. 2023. PMID: 36802203 Review.
Foster, and Paolo B. Dominelli. The impact of acetazolamide and methazolamide on exercise performance in normoxia and hypoxia. High Alt Med Biol. 24:7-18, 2023....In this review, we sought to examine how two CA inhibitors, acetazolamide (AZ) and methazolamide (MZ), …
Foster, and Paolo B. Dominelli. The impact of acetazolamide and methazolamide on exercise performance in normoxia and hypoxia. High A …
493 results