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Year Number of Results
1965 2
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1975 5
1976 3
1977 2
1978 1
1979 1
1980 2
1981 2
1982 5
1983 4
1984 3
1985 2
1986 2
1987 1
1989 1
1992 2
1993 1
1994 1
1996 1
1998 1
2000 3
2001 1
2002 2
2005 1
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2018 1
2019 1
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72 results

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Page 1
Alternative to prophylactic antibiotics for the treatment of recurrent urinary tract infections in women: multicentre, open label, randomised, non-inferiority trial.
Harding C, Mossop H, Homer T, Chadwick T, King W, Carnell S, Lecouturier J, Abouhajar A, Vale L, Watson G, Forbes R, Currer S, Pickard R, Eardley I, Pearce I, Thiruchelvam N, Guerrero K, Walton K, Hussain Z, Lazarowicz H, Ali A. Harding C, et al. BMJ. 2022 Mar 9;376:e068229. doi: 10.1136/bmj-2021-0068229. BMJ. 2022. PMID: 35264408 Free PMC article. Clinical Trial.
OBJECTIVE: To test and compare the efficacy of methenamine hippurate for prevention of recurrent urinary tract infections with the current standard prophylaxis of daily low dose antibiotics. ...RESULTS: Participants were randomly assigned to antibiotic prophylaxis (n=120) …
OBJECTIVE: To test and compare the efficacy of methenamine hippurate for prevention of recurrent urinary tract infections with the cu …
Methenamine hippurate compared with antibiotic prophylaxis to prevent recurrent urinary tract infections in women: the ALTAR non-inferiority RCT.
Harding C, Chadwick T, Homer T, Lecouturier J, Mossop H, Carnell S, King W, Abouhajar A, Vale L, Watson G, Forbes R, Currer S, Pickard R, Eardley I, Pearce I, Thiruchelvam N, Guerrero K, Walton K, Hussain Z, Lazarowicz H, Ali A. Harding C, et al. Health Technol Assess. 2022 May;26(23):1-172. doi: 10.3310/QOIZ6538. Health Technol Assess. 2022. PMID: 35535708 Free article. Clinical Trial.
Emerging antimicrobial resistance is a global health concern, prompting research interest in non-antibiotic agents such as methenamine hippurate, but comparative data on their efficacy and safety are lacking. OBJECTIVE: To assess the clinical effectiveness and cost-effecti …
Emerging antimicrobial resistance is a global health concern, prompting research interest in non-antibiotic agents such as methenamine …
Methenamine hippurate as prophylaxis for recurrent urinary tract infections in older women-a triple-blind, randomised, placebo-controlled, phase IV trial (ImpresU).
Heltveit-Olsen SR, Arnljots ES, Sundvall PD, Gunnarsson R, Kowalczyk A, Godycki-Cwirko M, Platteel TN, Groen WG, Lithén SS, Sundvall S, Åhrén C, Grude N, Verheij TJM, Hertogh CMPM, Lindbæk M, Høye S. Heltveit-Olsen SR, et al. Clin Microbiol Infect. 2025 Nov;31(11):1873-1879. doi: 10.1016/j.cmi.2025.07.006. Epub 2025 Jul 14. Clin Microbiol Infect. 2025. PMID: 40669691 Free article. Clinical Trial.
RESULTS: Of 289 recruited women, 281 (97%) were included in the main analysis (140 in the methenamine hippurate group, 141 in the placebo group). During the treatment period, the methenamine hippurate group had a lower incidence of antibiotic treatments for UTIs tha …
RESULTS: Of 289 recruited women, 281 (97%) were included in the main analysis (140 in the methenamine hippurate group, 141 in the pla …
Methenamine hippurate (Hiprex).
[No authors listed] [No authors listed] Med Lett Drugs Ther. 1968 Jul 26;10(15):58-60. Med Lett Drugs Ther. 1968. PMID: 4875552 Clinical Trial. No abstract available.
Methenamine hippurate compared with trimethoprim for the prevention of recurrent urinary tract infections: a randomized clinical trial.
Botros C, Lozo S, Iyer S, Warren A, Goldberg R, Tomezsko J, Sasso K, Sand P, Gafni-Kane A, Biener A, Botros-Brey S. Botros C, et al. Int Urogynecol J. 2022 Mar;33(3):571-580. doi: 10.1007/s00192-021-04849-0. Epub 2021 Jun 11. Int Urogynecol J. 2022. PMID: 34115162 Clinical Trial.
RESULTS: In the intent-to-treat analysis, we found no difference between groups in recurrent UTI, with a 65% (28 out of 43) recurrence in the trimethoprim group versus 65% (28 out of 43) in the methenamine hippurate group (p = 1.00). In the per-protocol analysis, 65% (26 o …
RESULTS: In the intent-to-treat analysis, we found no difference between groups in recurrent UTI, with a 65% (28 out of 43) recurrence in th …
Efficacy of methenamine with methylthioninium in the treatment of dysuria: a randomized clinical study.
Neto FS, Hachul H, Pereira MA, Filho CI. Neto FS, et al. Int Urogynecol J. 2023 Dec;34(12):3051-3058. doi: 10.1007/s00192-023-05669-0. Epub 2023 Oct 18. Int Urogynecol J. 2023. PMID: 37851092 Free PMC article. Clinical Trial.
This study evaluated the combination of methenamine 250 mg and methylthioninium chloride 20 mg in the treatment of dysuria versus phenazopyridine. ...Treatments were similar concerning time to reach the absence of symptoms and in the percentage of participants with sustain …
This study evaluated the combination of methenamine 250 mg and methylthioninium chloride 20 mg in the treatment of dysuria versus phe …
Topical methenamine therapy for hyperhidrosis.
Cullen SI. Cullen SI. Arch Dermatol. 1975 Sep;111(9):1158-60. Arch Dermatol. 1975. PMID: 1167048 Clinical Trial.
Methenamine, in a gel stick formulation, effectively decreased palmar and plantar sweating in 24 of 26 individuals studied. All patients had essential hyperhidrosis and were evaluated in a double-blind, placebo-controlled study. Even though methenamine is believed t …
Methenamine, in a gel stick formulation, effectively decreased palmar and plantar sweating in 24 of 26 individuals studied. All patie …
Long-term prophylaxis of urinary infections in women: comparative trial of trimethoprim, methenamine hippurate and topical povidone-iodine.
Brumfitt W, Hamilton-Miller JM, Gargan RA, Cooper J, Smith GW. Brumfitt W, et al. J Urol. 1983 Dec;130(6):1110-4. doi: 10.1016/s0022-5347(17)51709-7. J Urol. 1983. PMID: 6227756 Clinical Trial.
We randomized 64 patients with a history of recurrent urinary tract infections among 3 regimens of long-term (1 year) prophylactic treatment: 20 were given 100 mg. trimethoprim at night, 25 received 1,000 mg. methenamine hippurate every 12 hours and 19 were asked to cleans …
We randomized 64 patients with a history of recurrent urinary tract infections among 3 regimens of long-term (1 year) prophylactic treatment …
Prevention of recurrent urinary infections in women: a comparative trial between nitrofurantoin and methenamine hippurate.
Brumfitt W, Cooper J, Hamilton-Miller JM. Brumfitt W, et al. J Urol. 1981 Jul;126(1):71-4. doi: 10.1016/s0022-5347(17)54386-4. J Urol. 1981. PMID: 7019458 Clinical Trial.
We treated 99 female patients suffering from recurrent urinary infections with either 1 gm. methenamine hippurate every 12 hours or 50 mg. nitrofurantoin every 12 hours for intervals of up to 1 year. ...Especially during the first month of treatment methenamine hipp …
We treated 99 female patients suffering from recurrent urinary infections with either 1 gm. methenamine hippurate every 12 hours or 5 …
The use of Methenamine as an antiperspirant for amputees.
Susak Z, Minkov R, Isakov E. Susak Z, et al. Prosthet Orthot Int. 1996 Dec;20(3):172-5. doi: 10.3109/03093649609164439. Prosthet Orthot Int. 1996. PMID: 8985996 Clinical Trial.
Methenamine was used on the stump of sixteen amputees. The trial was conducted as a double blind study using two different solutions market as solution A and as solution B. ...The use of Methenamine as an antiperspirant is recommended in amputation stumps....
Methenamine was used on the stump of sixteen amputees. The trial was conducted as a double blind study using two different solutions …
72 results