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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1953 1
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1957 5
1958 8
1959 10
1960 8
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1962 7
1963 4
1964 10
1965 5
1966 5
1967 6
1968 5
1969 3
1970 6
1971 9
1972 1
1973 4
1974 5
1975 7
1976 2
1977 3
1978 1
1979 3
1980 1
1981 2
1982 5
1984 5
1985 2
1986 4
1987 1
1988 1
1989 2
1990 6
1991 2
1992 7
1993 3
1994 2
1995 2
1997 2
1998 4
1999 3
2000 2
2001 1
2002 3
2003 1
2004 3
2005 2
2006 1
2007 1
2008 3
2009 8
2010 8
2011 8
2012 7
2013 12
2014 8
2015 8
2016 8
2017 11
2018 5
2019 12
2020 8
2021 15
2022 19
2023 17
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368 results

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Page 1
Choosing a skeletal muscle relaxant.
See S, Ginzburg R. See S, et al. Am Fam Physician. 2008 Aug 1;78(3):365-70. Am Fam Physician. 2008. PMID: 18711953 Free article. Review.
The sedative properties of tizanidine and cyclobenzaprine may benefit patients with insomnia caused by severe muscle spasms. Methocarbamol and metaxalone are less sedating, although effectiveness evidence is limited. ...
The sedative properties of tizanidine and cyclobenzaprine may benefit patients with insomnia caused by severe muscle spasms. Methocarbamo
Methocarbamol.
[No authors listed] [No authors listed] 2017 Jan 30. LiverTox: Clinical and Research Information on Drug-Induced Liver Injury [Internet]. Bethesda (MD): National Institute of Diabetes and Digestive and Kidney Diseases; 2012–. 2017 Jan 30. LiverTox: Clinical and Research Information on Drug-Induced Liver Injury [Internet]. Bethesda (MD): National Institute of Diabetes and Digestive and Kidney Diseases; 2012–. PMID: 31643609 Free Books & Documents. Review.
Methocarbamol is a commonly used, centrally acting muscle relaxant and has not been linked to instances of liver injury....
Methocarbamol is a commonly used, centrally acting muscle relaxant and has not been linked to instances of liver injury....
Commentary: Is Polyethylene Glycol Toxicity From Intravenous Methocarbamol Fact or Fiction?
Chan E, Waggoner C, Boylan PM. Chan E, et al. J Pain Palliat Care Pharmacother. 2024 Jun;38(2):180-184. doi: 10.1080/15360288.2024.2345322. Epub 2024 May 8. J Pain Palliat Care Pharmacother. 2024. PMID: 38718034
Methocarbamol is an antispasmodic muscle relaxant and was the fourth most-prescribed muscle relaxant by volume in the United States in 2021. Intravenous (IV) methocarbamol contains the excipient, polyethylene glycol (PEG), which has been implicated in metabolic acid
Methocarbamol is an antispasmodic muscle relaxant and was the fourth most-prescribed muscle relaxant by volume in the United States i
Pharmacotherapy for Spine-Related Pain in Older Adults.
Fu JL, Perloff MD. Fu JL, et al. Drugs Aging. 2022 Jul;39(7):523-550. doi: 10.1007/s40266-022-00946-x. Epub 2022 Jun 27. Drugs Aging. 2022. PMID: 35754070 Free article. Review.
Some muscle relaxants (carisoprodol, chlorzoxazone, cyclobenzaprine, metaxalone, methocarbamol, and orphenadrine) are avoided in older adults due to risk for sedation and falls. ...
Some muscle relaxants (carisoprodol, chlorzoxazone, cyclobenzaprine, metaxalone, methocarbamol, and orphenadrine) are avoided in olde …
Methocarbamol.
[No authors listed] [No authors listed] 2025 Sep 15. Drugs and Lactation Database (LactMed®) [Internet]. Bethesda (MD): National Institute of Child Health and Human Development; 2006–. 2025 Sep 15. Drugs and Lactation Database (LactMed®) [Internet]. Bethesda (MD): National Institute of Child Health and Human Development; 2006–. PMID: 40986685 Free Books & Documents. Review.
No information is available on the use of methocarbamol during breastfeeding. If a mother requires methocarbamol, it is not a reason to discontinue breastfeeding. ...
No information is available on the use of methocarbamol during breastfeeding. If a mother requires methocarbamol, it is not a …
Methocarbamol.
Sibrack J, Patel P, Hammer R. Sibrack J, et al. 2024 Sep 10. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2026 Jan–. 2024 Sep 10. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2026 Jan–. PMID: 33351427 Free Books & Documents.
Classified as a skeletal muscle relaxant, methocarbamol is a helpful medication used to manage acute musculoskeletal pain. This activity focuses on the pivotal indications, mechanism of action, and contraindications of methocarbamol in the treatment mosaic for acute …
Classified as a skeletal muscle relaxant, methocarbamol is a helpful medication used to manage acute musculoskeletal pain. This activ …
Comparative efficacy and safety of skeletal muscle relaxants for spasticity and musculoskeletal conditions: a systematic review.
Chou R, Peterson K, Helfand M. Chou R, et al. J Pain Symptom Manage. 2004 Aug;28(2):140-75. doi: 10.1016/j.jpainsymman.2004.05.002. J Pain Symptom Manage. 2004. PMID: 15276195 Free article.
There is very limited or inconsistent data regarding the effectiveness of metaxalone, methocarbamol, chlorzoxazone, baclofen, or dantrolene compared to placebo in patients with musculoskeletal conditions. There is insufficient evidence to determine the relative efficacy or …
There is very limited or inconsistent data regarding the effectiveness of metaxalone, methocarbamol, chlorzoxazone, baclofen, or dant …
The Relative Efficacy of Seven Skeletal Muscle Relaxants. An Analysis of Data From Randomized Studies.
Abril L, Zamora C, Cordero M, Williams AR, Friedman BW. Abril L, et al. J Emerg Med. 2022 Apr;62(4):455-461. doi: 10.1016/j.jemermed.2021.09.025. Epub 2022 Jan 20. J Emerg Med. 2022. PMID: 35067395
We compared the change in RMDQ among 8 groups: placebo, baclofen, metaxalone, tizanidine, diazepam, orphenadrine, methocarbamol, and cyclobenzaprine. All patients also received a nonsteroidal anti-inflammatory drug. ...RESULTS: The mean improvement in RMDQ per group was pl …
We compared the change in RMDQ among 8 groups: placebo, baclofen, metaxalone, tizanidine, diazepam, orphenadrine, methocarbamol, and …
Alternatives to Opioids for Managing Pain.
Dey S, Sanders AE, Martinez S, Kopitnik NL, Vrooman BM. Dey S, et al. 2024 Nov 25. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2026 Jan–. 2024 Nov 25. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2026 Jan–. PMID: 34662057 Free Books & Documents.
Other treatment options include muscle relaxants (eg, methocarbamol), baclofen, cyclobenzaprine, and, less commonly, carisoprodol, which has street value and potential widespread abuse similar to benzodiazepines. ...
Other treatment options include muscle relaxants (eg, methocarbamol), baclofen, cyclobenzaprine, and, less commonly, carisoprodol, wh …
Association Between Postoperative Methocarbamol and Postoperative Pain Opioid Dose Requirements: A Retrospective Cohort Study.
Komatsu R, Singleton MD, Wu J, Dinges EM, Bollag LA. Komatsu R, et al. Clin J Pain. 2023 Sep 1;39(9):452-457. doi: 10.1097/AJP.0000000000001137. Clin J Pain. 2023. PMID: 37284760
OBJECTIVES: We tested the hypothesis that patients who received methocarbamol postoperatively experience less severe pain and require smaller doses of opioids than those who did not receive methocarbamol. ...RESULTS: Postoperative 48-hour TWA pain scores were 5.5 1. …
OBJECTIVES: We tested the hypothesis that patients who received methocarbamol postoperatively experience less severe pain and require …
368 results