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Year Number of Results
1968 1
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29 results

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Page 1
Methocarbamol versus diazepam in acute low back pain in the emergency department: a randomised double-blind clinical trial.
Sharifi M, Abdorazzaghnejad A, Yazdchi M, Bahreini M. Sharifi M, et al. Emerg Med J. 2023 Jul;40(7):493-498. doi: 10.1136/emermed-2021-211485. Epub 2023 Apr 17. Emerg Med J. 2023. PMID: 37068928 Clinical Trial.
RESULTS: Out of 101 enrolled patients, 50 participants received methocarbamol and 51 diazepam. The baseline mean pain scores and demographic characteristics were not different between the study groups. ...CONCLUSIONS: In patients with LBP, the pain was relieved in the m …
RESULTS: Out of 101 enrolled patients, 50 participants received methocarbamol and 51 diazepam. The baseline mean pain scores and demo …
The pharmacology and pharmacokinetics of high-dose methocarbamol in horses.
Muir WW 3rd, Sams RA, Ashcraft S. Muir WW 3rd, et al. Equine Vet J Suppl. 1992 Feb;(11):41-4. doi: 10.1111/j.2042-3306.1992.tb04771.x. Equine Vet J Suppl. 1992. PMID: 9109959 Clinical Trial.
Heart rate, cardiac output, mean pulmonary arterial blood pressure, systolic, diastolic and mean aortic blood pressure, respiratory rate and arterial blood gases did not change after either i.v. (30 mg/kg bodyweight [bwt]) or oral (50 and 100 mg/kg bwt) dosages of methocarbamo …
Heart rate, cardiac output, mean pulmonary arterial blood pressure, systolic, diastolic and mean aortic blood pressure, respiratory rate and …
Subjective and behavioral effects of diphenhydramine, lorazepam and methocarbamol: evaluation of abuse liability.
Preston KL, Wolf B, Guarino JJ, Griffiths RR. Preston KL, et al. J Pharmacol Exp Ther. 1992 Aug;262(2):707-20. J Pharmacol Exp Ther. 1992. PMID: 1501118 Clinical Trial.
The effects of orally administered placebo, diphenhydramine, lorazepam, methocarbamol and placebo were studied in volunteers with histories of recreational substance abuse including sedative/hypnotics. Placebo, diphenhydramine (100, 200 and 400 mg), lorazepam (1 and 4 mg) …
The effects of orally administered placebo, diphenhydramine, lorazepam, methocarbamol and placebo were studied in volunteers with his …
Evaluation of the abuse potential of methocarbamol.
Preston KL, Guarino JJ, Kirk WT, Griffiths RR. Preston KL, et al. J Pharmacol Exp Ther. 1989 Mar;248(3):1146-57. J Pharmacol Exp Ther. 1989. PMID: 2703967 Clinical Trial.
The following drug conditions were tested in the cross-over phase: placebo, lorazepam 1, 2 and 4 mg, and methocarbamol 2.25, 4.5 and 9 g. Drug conditions were tested under double-blind conditions. ...Methocarbamol also increased ratings on measures indicating the em …
The following drug conditions were tested in the cross-over phase: placebo, lorazepam 1, 2 and 4 mg, and methocarbamol 2.25, 4.5 and …
The pharmacokinetics of methocarbamol and guaifenesin after single intravenous and multiple-dose oral administration of methocarbamol in the horse.
Rumpler MJ, Colahan P, Sams RA. Rumpler MJ, et al. J Vet Pharmacol Ther. 2014 Feb;37(1):25-34. doi: 10.1111/jvp.12068. Epub 2013 Jul 17. J Vet Pharmacol Ther. 2014. PMID: 23859819 Clinical Trial.
A simple LC/MSMS method has been developed and fully validated to determine concentrations and characterize the concentration vs. time course of methocarbamol (MCBL) and guaifenesin (GGE) in plasma after a single intravenous dose and multiple oral dose administrations of M …
A simple LC/MSMS method has been developed and fully validated to determine concentrations and characterize the concentration vs. time cours …
Randomized-controlled trial of methocarbamol as a novel treatment for muscle cramps in cirrhotic patients.
Abd-Elsalam S, Arafa M, Elkadeem M, Elfert A, Soliman S, Elkhalawany W, Badawi R. Abd-Elsalam S, et al. Eur J Gastroenterol Hepatol. 2019 Apr;31(4):499-502. doi: 10.1097/MEG.0000000000001310. Eur J Gastroenterol Hepatol. 2019. PMID: 30444744 Clinical Trial.
Half of these patients received methocarbamol and the other half received placebo. This was done through equal randomization. ...However, no significant changes were observed in the placebo group. Few side effects of methocarbamol were recorded, including dry mouth …
Half of these patients received methocarbamol and the other half received placebo. This was done through equal randomization. ...Howe …
[Methocarbamol in acute low back pain. A randomized double-blind controlled study].
Emrich OM, Milachowski KA, Strohmeier M. Emrich OM, et al. MMW Fortschr Med. 2015 Jul;157 Suppl 5:9-16. doi: 10.1007/s15006-015-3307-x. Epub 2015 Jul 13. MMW Fortschr Med. 2015. PMID: 26168743 Clinical Trial. German.
For this indication, the European Medicines Agency (EMA) recently had imposed restrictions for some muscle relaxants, anti-inflammatories and analgesics; Tetrazepam even had to be withdrawn from the market. Therefore methocarbamol remains the only approved muscle relaxant. …
For this indication, the European Medicines Agency (EMA) recently had imposed restrictions for some muscle relaxants, anti-inflammatories an …
Does methocarbamol affect fatigue markers in the low-back electromyogram?
Boakes J, Peach JP, McGill SM. Boakes J, et al. J Electromyogr Kinesiol. 1998 Dec;8(6):423-7. doi: 10.1016/s1050-6411(98)00017-0. J Electromyogr Kinesiol. 1998. PMID: 9840897 Clinical Trial.
The question that needed to be addressed was, do centrally acting muscle relaxants (methocarbamol; Robaxin) affect the EMG spectral indices of muscle fatigue that are often used to assess muscle performance. ...Specifically, the following parameters were studied in the bil …
The question that needed to be addressed was, do centrally acting muscle relaxants (methocarbamol; Robaxin) affect the EMG spectral i …
29 results