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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1966 3
1967 5
1968 5
1969 6
1970 6
1971 6
1972 4
1973 17
1974 22
1975 54
1976 29
1977 17
1978 15
1979 16
1980 19
1981 15
1982 22
1983 38
1984 36
1985 36
1986 37
1987 49
1988 51
1989 58
1990 63
1991 63
1992 78
1993 110
1994 109
1995 91
1996 89
1997 85
1998 121
1999 96
2000 95
2001 70
2002 67
2003 87
2004 94
2005 99
2006 120
2007 104
2008 84
2009 68
2010 82
2011 89
2012 81
2013 72
2014 77
2015 93
2016 80
2017 69
2018 68
2019 54
2020 46
2021 73
2022 56
2023 45
2024 37
2025 44
2026 19

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3,198 results

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Page 1
Administration of methylprednisolone for 24 or 48 hours or tirilazad mesylate for 48 hours in the treatment of acute spinal cord injury. Results of the Third National Acute Spinal Cord Injury Randomized Controlled Trial. National Acute Spinal Cord Injury Study.
Bracken MB, Shepard MJ, Holford TR, Leo-Summers L, Aldrich EF, Fazl M, Fehlings M, Herr DL, Hitchon PW, Marshall LF, Nockels RP, Pascale V, Perot PL Jr, Piepmeier J, Sonntag VK, Wagner F, Wilberger JE, Winn HR, Young W. Bracken MB, et al. JAMA. 1997 May 28;277(20):1597-604. JAMA. 1997. PMID: 9168289 Clinical Trial.
RESULTS: Compared with patients treated with methylprednisolone for 24 hours, those treated with methylprednisolone for 48 hours showed improved motor recovery at 6 weeks (P=.09) and 6 months (P=.07) after injury. ...When methylprednisolone is initiated 3 to …
RESULTS: Compared with patients treated with methylprednisolone for 24 hours, those treated with methylprednisolone for 48 hou …
Efficacy and safety of corticosteroids for persistent acute respiratory distress syndrome.
Steinberg KP, Hudson LD, Goodman RB, Hough CL, Lanken PN, Hyzy R, Thompson BT, Ancukiewicz M; National Heart, Lung, and Blood Institute Acute Respiratory Distress Syndrome (ARDS) Clinical Trials Network. Steinberg KP, et al. N Engl J Med. 2006 Apr 20;354(16):1671-84. doi: 10.1056/NEJMoa051693. N Engl J Med. 2006. PMID: 16625008 Free article. Clinical Trial.
CONCLUSIONS: These results do not support the routine use of methylprednisolone for persistent ARDS despite the improvement in cardiopulmonary physiology. In addition, starting methylprednisolone therapy more than two weeks after the onset of ARDS may increase the r …
CONCLUSIONS: These results do not support the routine use of methylprednisolone for persistent ARDS despite the improvement in cardio …
A randomized, controlled trial of corticosteroids in the treatment of acute optic neuritis. The Optic Neuritis Study Group.
Beck RW, Cleary PA, Anderson MM Jr, Keltner JL, Shults WT, Kaufman DI, Buckley EG, Corbett JJ, Kupersmith MJ, Miller NR, et al. Beck RW, et al. N Engl J Med. 1992 Feb 27;326(9):581-8. doi: 10.1056/NEJM199202273260901. N Engl J Med. 1992. PMID: 1734247 Free article. Clinical Trial.
RESULTS: Visual function recovered faster in the group receiving intravenous methylprednisolone than in the placebo group; this was particularly true for the reversal of visual-field defects (P = 0.0001). ...CONCLUSIONS: Intravenous methylprednisolone followed by or …
RESULTS: Visual function recovered faster in the group receiving intravenous methylprednisolone than in the placebo group; this was p …
Methylprednisolone for Infant Heart Surgery: Subpopulation Analyses of a Randomized Controlled Trial.
Sunthankar SD, Hill KD, Jacobs JP, Baldwin HS, Jacobs ML, Li JS, Graham EM, Blasiole B, Husain SA, Bleiweis MS, Mettler B, Benscoter A, Wald E, Karamlou T, Van Bergen AH, Eghtesady P, Scott JP, Anderson BR, Alfieris G, Vener DF, Kannankeril PJ. Sunthankar SD, et al. Crit Care Med. 2025 Jul 1;53(7):e1470-e1480. doi: 10.1097/CCM.0000000000006721. Epub 2025 May 21. Crit Care Med. 2025. PMID: 40396812 Free PMC article. Clinical Trial.
No increase in overall infection or reduction in prolonged mechanical ventilation with methylprednisolone. CONCLUSIONS: Both beneficial and adverse associations were observed with prophylactic methylprednisolone. Reduction in postoperative hydrocortisone administrat …
No increase in overall infection or reduction in prolonged mechanical ventilation with methylprednisolone. CONCLUSIONS: Both benefici …
Comparison of the effect of intravenous dexamethasone and methylprednisolone on the treatment of hospitalized patients with COVID-19: a randomized clinical trial.
Dastenae ZH, Bahadori A, Dehghani M, Asadi-Samani M, Izadi I, Shahraki HR. Dastenae ZH, et al. Int J Infect Dis. 2022 Sep;122:659-664. doi: 10.1016/j.ijid.2022.07.019. Epub 2022 Jul 9. Int J Infect Dis. 2022. PMID: 35817286 Free PMC article. Clinical Trial.
OBJECTIVE: In this study, we aimed to compare the effects of intravenous dexamethasone and methylprednisolone on the treatment of inpatients with COVID-19. METHODS: In this randomized clinical trial, 143 patients under 80 years of age with moderate to severe COVID-19 were …
OBJECTIVE: In this study, we aimed to compare the effects of intravenous dexamethasone and methylprednisolone on the treatment of inp …
Steroids in bronchitis.
[No authors listed] [No authors listed] Br Med J. 1980 Oct 25;281(6248):1088-9. Br Med J. 1980. PMID: 7000290 Free PMC article. Clinical Trial. No abstract available.
Methylprednisolone pulse therapy compared with intravenous dexamethasone for severe COVID-19 patients: a randomized clinical trial.
Haratian K, Alaei A, Mehrpoor G, Gargari OK. Haratian K, et al. Virol J. 2025 Aug 6;22(1):270. doi: 10.1186/s12985-025-02906-4. Virol J. 2025. PMID: 40770358 Free PMC article. Clinical Trial.
The mortality rate was 12.6% in the dexamethasone group and 15.3% in the methylprednisolone group, with no statistically significant difference (RR: 0.82, P = 0.50). The need for mechanical ventilation was observed in 16.6% of patients in the dexamethasone group and 21.3% …
The mortality rate was 12.6% in the dexamethasone group and 15.3% in the methylprednisolone group, with no statistically significant …
Methylprednisolone as Adjunct to Thrombectomy for Acute Intracranial Internal Carotid Artery Occlusion Stroke: Post Hoc Secondary Analysis of the MARVEL Randomized Clinical Trial.
Zheng C, Li R, Shen C, Guo F, Fan D, Yang L, Zhang L, Chen A, Chen Y, Chen D, Zi W, Guo C, Nguyen TN, Albers GW, Campbell BCV, Qiu Z, Hu Z. Zheng C, et al. JAMA Netw Open. 2025 Feb 3;8(2):e2459945. doi: 10.1001/jamanetworkopen.2024.59945. JAMA Netw Open. 2025. PMID: 39964685 Free PMC article. Clinical Trial.
OBJECTIVE: To investigate the effectiveness and safety associated with intravenous methylprednisolone as adjunctive treatment to EVT for patients with AIS due to intracranial ICA occlusion. ...CONCLUSIONS AND RELEVANCE: In this secondary analysis of a randomized clinical t …
OBJECTIVE: To investigate the effectiveness and safety associated with intravenous methylprednisolone as adjunctive treatment to EVT …
Controlled clinical trial of methylprednisolone in patients with chronic bronchitis and acute respiratory insufficiency.
Albert RK, Martin TR, Lewis SW. Albert RK, et al. Ann Intern Med. 1980 Jun;92(6):753-8. doi: 10.7326/0003-4819-92-6-753. Ann Intern Med. 1980. PMID: 6770731 Clinical Trial.
The methylprednisolone-treated group had a greater improvement in both prebronchodilator and postbronchodilator forced expiratory volume in 1 second (P less than 0.001). More patients with large improvements in their prebronchodilator or postbronchodilator flow rates, or b …
The methylprednisolone-treated group had a greater improvement in both prebronchodilator and postbronchodilator forced expiratory vol …
3,198 results