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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1946 1
1947 1
1950 2
1951 3
1952 1
1953 1
1954 2
1955 4
1957 1
1959 2
1960 2
1962 1
1963 3
1964 5
1965 1
1966 1
1967 3
1968 2
1969 27
1970 8
1971 14
1972 26
1973 35
1974 61
1975 63
1976 60
1977 44
1978 48
1979 58
1980 40
1981 35
1982 45
1983 53
1984 45
1985 61
1986 61
1987 56
1988 73
1989 78
1990 94
1991 82
1992 106
1993 109
1994 135
1995 145
1996 140
1997 138
1998 156
1999 140
2000 161
2001 163
2002 147
2003 196
2004 210
2005 243
2006 294
2007 320
2008 380
2009 380
2010 455
2011 439
2012 473
2013 481
2014 504
2015 530
2016 568
2017 562
2018 446
2019 425
2020 477
2021 472
2022 469
2023 490
2024 524
2025 85

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10,999 results

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Page 1
Minocycline and Doxycycline: More Than Antibiotics.
Singh S, Khanna D, Kalra S. Singh S, et al. Curr Mol Pharmacol. 2021;14(6):1046-1065. doi: 10.2174/1874467214666210210122628. Curr Mol Pharmacol. 2021. PMID: 33568043 Review.
Minocycline and doxycycline both are second-generation tetracycline antibiotics with similar chemical structures and comparable antibacterial spectrum. ...Minocycline showed promising results in experimental neurology, which was due to its highly lipophilic nature.
Minocycline and doxycycline both are second-generation tetracycline antibiotics with similar chemical structures and comparable antib
Minocycline.
Jonas M, Cunha BA. Jonas M, et al. Ther Drug Monit. 1982;4(2):137-45. Ther Drug Monit. 1982. PMID: 7048646 Review.
Minocycline, a second generation tetracycline derivative, was first introduced in 1967. The following review considers the physiochemical and pharmacokinetic properties, antimicrobial activity, clinical uses, and adverse effects of minocycline. Excellent tissue and
Minocycline, a second generation tetracycline derivative, was first introduced in 1967. The following review considers the physiochem
Effect of Minocycline on Depressive Symptoms in Patients With Treatment-Resistant Depression: A Randomized Clinical Trial.
Hellmann-Regen J, Clemens V, Grözinger M, Kornhuber J, Reif A, Prvulovic D, Goya-Maldonado R, Wiltfang J, Gruber O, Schüle C, Padberg F, Ising M, Uhr M, Friede T, Huber C, Manook A, Baghai TC, Rupprecht R, Heuser I. Hellmann-Regen J, et al. JAMA Netw Open. 2022 Sep 1;5(9):e2230367. doi: 10.1001/jamanetworkopen.2022.30367. JAMA Netw Open. 2022. PMID: 36103181 Free PMC article. Clinical Trial.
Minocycline treatment also exhibited no statistically significant effect on secondary outcomes. CONCLUSIONS AND RELEVANCE: In this large randomized clinical trial with minocycline at a dose of 200 mg/d added to antidepressant treatment as usual for 6 weeks, minoc
Minocycline treatment also exhibited no statistically significant effect on secondary outcomes. CONCLUSIONS AND RELEVANCE: In this la
Minocycline.
Allen JC. Allen JC. Ann Intern Med. 1976 Oct;85(4):482-7. doi: 10.7326/0003-4819-85-4-482. Ann Intern Med. 1976. PMID: 788583 Review.
Minocycline has proved to have a wider spectrum of activity against both aerobic and anaerobic bacteria and has enhanced tissue penetration when compared with its tetracycline congeners. ...Though data on the frequency and severity of these symptoms are in some conflict,
Minocycline has proved to have a wider spectrum of activity against both aerobic and anaerobic bacteria and has enhanced tissue penet
Minocycline prevents hypoxia-induced seizures.
Fukushi I, Ikeda K, Takeda K, Yoshizawa M, Kono Y, Hasebe Y, Pokorski M, Okada Y. Fukushi I, et al. Front Neural Circuits. 2023 Mar 22;17:1006424. doi: 10.3389/fncir.2023.1006424. eCollection 2023. Front Neural Circuits. 2023. PMID: 37035503 Free PMC article.
Then, we analyzed the effects of minocycline pre-treatment on ventilatory responses to hypoxia by plethysmography. Minocycline alone failed to affect respiratory variables in room air or the initial respiratory augmentation in hypoxia. The comparative results showed …
Then, we analyzed the effects of minocycline pre-treatment on ventilatory responses to hypoxia by plethysmography. Minocycline
Tigecycline.
Pankey GA. Pankey GA. J Antimicrob Chemother. 2005 Sep;56(3):470-80. doi: 10.1093/jac/dki248. Epub 2005 Jul 22. J Antimicrob Chemother. 2005. PMID: 16040625 Review.
Tigecycline, the first in a new class of antimicrobials, the glycylcyclines, is an analogue of minocycline with additional properties that negate most mechanisms mediating resistance to the tetracyclines. ...
Tigecycline, the first in a new class of antimicrobials, the glycylcyclines, is an analogue of minocycline with additional properties …
Tigecycline.
Frampton JE, Curran MP. Frampton JE, et al. Drugs. 2005;65(18):2623-35; discussion 2636-7. doi: 10.2165/00003495-200565180-00008. Drugs. 2005. PMID: 16392879 Review.
Re-defining tigecycline therapy.
De Rosa FG, Corcione S, Di Perri G, Scaglione F. De Rosa FG, et al. New Microbiol. 2015 Apr;38(2):121-36. Epub 2015 Apr 21. New Microbiol. 2015. PMID: 25915055 Free article. Review.
Tigecycline: an update.
Stein GE, Babinchak T. Stein GE, et al. Diagn Microbiol Infect Dis. 2013 Apr;75(4):331-6. doi: 10.1016/j.diagmicrobio.2012.12.004. Epub 2013 Jan 26. Diagn Microbiol Infect Dis. 2013. PMID: 23357291 Review.
Tetracyclines enhance antitumor T-cell immunity via the Zap70 signaling pathway.
Tone M, Iwahori K, Hirata M, Ueyama A, Tani A, Haruta JI, Takeda Y, Shintani Y, Kumanogoh A, Wada H. Tone M, et al. J Immunother Cancer. 2024 Apr 15;12(4):e008334. doi: 10.1136/jitc-2023-008334. J Immunother Cancer. 2024. PMID: 38621815 Free PMC article.
The analysis of T-cell signaling showed that CD69 in both CD4(+) and CD8(+) T cells was upregulated by minocycline. Downstream of T-cell receptor signaling, Zap70 phosphorylation and Nur77 were also upregulated by minocycline in the early phase after T-cell activati …
The analysis of T-cell signaling showed that CD69 in both CD4(+) and CD8(+) T cells was upregulated by minocycline. Downstream of T-c …
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