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1981 1
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1990 73
1991 110
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1998 155
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2005 255
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Misoprostol for induction of labor.
Stephenson ML, Wing DA. Stephenson ML, et al. Semin Perinatol. 2015 Oct;39(6):459-62. doi: 10.1053/j.semperi.2015.07.008. Semin Perinatol. 2015. PMID: 26601733 Review.
With up to half of all induced labors requiring cervical ripening, prostaglandins have been utilized to increase induction success and achieve vaginal delivery. Misoprostol, a synthetic prostaglandin E1 analog has the ability to mimic the changes of spontaneous labor and h …
With up to half of all induced labors requiring cervical ripening, prostaglandins have been utilized to increase induction success and achie …
Misoprostol: pharmacokinetic profiles, effects on the uterus and side-effects.
Tang OS, Gemzell-Danielsson K, Ho PC. Tang OS, et al. Int J Gynaecol Obstet. 2007 Dec;99 Suppl 2:S160-7. doi: 10.1016/j.ijgo.2007.09.004. Epub 2007 Oct 26. Int J Gynaecol Obstet. 2007. PMID: 17963768 Review.
It can be given orally, vaginally, sublingually, buccally or rectally. Studies of misoprostol's pharmacokinetics and effects on uterine activity have demonstrated the properties of the drug after various routes of administration. These studies can help to discover t …
It can be given orally, vaginally, sublingually, buccally or rectally. Studies of misoprostol's pharmacokinetics and effects o …
A systematic review and network meta-analysis comparing the use of Foley catheters, misoprostol, and dinoprostone for cervical ripening in the induction of labour.
Chen W, Xue J, Peprah MK, Wen SW, Walker M, Gao Y, Tang Y. Chen W, et al. BJOG. 2016 Feb;123(3):346-54. doi: 10.1111/1471-0528.13456. Epub 2015 Nov 5. BJOG. 2016. PMID: 26538408 Review.
The use of a Foley catheter to induce labour was associated with the lowest rate of uterine hyperstimulation accompanied by FHR changes. The caesarean section rate was lowest using oral misoprostol for the induction of labour. AUTHOR'S CONCLUSIONS: No method of labo …
The use of a Foley catheter to induce labour was associated with the lowest rate of uterine hyperstimulation accompanied by FHR changes. The …
Misoprostol for medical treatment of missed abortion: a systematic review and network meta-analysis.
Wu HL, Marwah S, Wang P, Wang QM, Chen XW. Wu HL, et al. Sci Rep. 2017 May 10;7(1):1664. doi: 10.1038/s41598-017-01892-0. Sci Rep. 2017. PMID: 28490770 Free PMC article.
In terms of efficacy, the most effective treatment was sublingual misoprostol of 600 ug and the least effective was oral misoprostol of 400 ug. ...Sublingual misoprostol of 600 ug or vaginal misoprostol of 800 ug may be a good choice for the first dose …
In terms of efficacy, the most effective treatment was sublingual misoprostol of 600 ug and the least effective was oral misoprost
Oral misoprostol, low dose vaginal misoprostol, and vaginal dinoprostone for labor induction: Randomized controlled trial.
Young DC, Delaney T, Armson BA, Fanning C. Young DC, et al. PLoS One. 2020 Jan 10;15(1):e0227245. doi: 10.1371/journal.pone.0227245. eCollection 2020. PLoS One. 2020. PMID: 31923193 Free PMC article. Clinical Trial.
Mean time (SD) to vaginal birth was 1356 (1033) minutes for oral misoprostol, 1530 (3249) minutes for vaginal misoprostol, and 1208 (613) minutes for vaginal dinoprostone (P = 0.46, ANOVA). ...Profound newborn acidemia, though infrequent, occurred only with low dose …
Mean time (SD) to vaginal birth was 1356 (1033) minutes for oral misoprostol, 1530 (3249) minutes for vaginal misoprostol, and …
Efficacy of Misoprostol Alone for First-Trimester Medical Abortion: A Systematic Review.
Raymond EG, Harrison MS, Weaver MA. Raymond EG, et al. Obstet Gynecol. 2019 Jan;133(1):137-147. doi: 10.1097/AOG.0000000000003017. Obstet Gynecol. 2019. PMID: 30531568 Free PMC article.
OBJECTIVE: To summarize available data on the effectiveness and safety of single-agent misoprostol for medical abortion in the first trimester. DATA SOURCES: We searched MEDLINE, CABI, Cochrane, EMBASE, LILACS, the Web of Science, and ClinicalTrials.gov for English-languag …
OBJECTIVE: To summarize available data on the effectiveness and safety of single-agent misoprostol for medical abortion in the first …
Oral or Vaginal Misoprostol for Labor Induction and Cesarean Delivery Risk.
Handal-Orefice RC, Friedman AM, Chouinard SM, Eke AC, Feinberg B, Politch J, Iverson RE, Yarrington CD. Handal-Orefice RC, et al. Obstet Gynecol. 2019 Jul;134(1):10-16. doi: 10.1097/AOG.0000000000003274. Obstet Gynecol. 2019. PMID: 31188317
Labor induction using 25 micrograms vaginal misoprostol in 2013-2014 was compared with 50 micrograms oral misoprostol in 2014-2015. ...Tachysystole occurred more frequently with vaginal misoprostol (20% vs 11%; P=.04). CONCLUSION: Compared with vaginal mis
Labor induction using 25 micrograms vaginal misoprostol in 2013-2014 was compared with 50 micrograms oral misoprostol in 2014- …
Early medical abortion with self-administered low-dose mifepristone in combination with misoprostol.
Song LP, Tang SY, Li CL, Zhou LJ, Mo XT. Song LP, et al. J Obstet Gynaecol Res. 2018 Sep;44(9):1705-1711. doi: 10.1111/jog.13716. Epub 2018 Jul 5. J Obstet Gynaecol Res. 2018. PMID: 29974571 Free PMC article.
AIM: The aim of the present study was to investigate the safety and efficacy of low-dose mifepristone combined with self-administered misoprostol for termination of early pregnancy. METHODS: A total of 533 women seeking medical abortion in early pregnancy (49 days since th …
AIM: The aim of the present study was to investigate the safety and efficacy of low-dose mifepristone combined with self-administered mis
[Misoprostol: off-label use in the treatment of post-partum hemorrhage].
Garrigue A, Pierre F. Garrigue A, et al. J Gynecol Obstet Biol Reprod (Paris). 2014 Feb;43(2):179-89. doi: 10.1016/j.jgyn.2013.11.011. Epub 2014 Jan 20. J Gynecol Obstet Biol Reprod (Paris). 2014. PMID: 24457021 Review. French.
Use of misoprostol is associated with a higher risk of using other uterotonics (P<0.001). ...Combined use of misoprostol and oxytocin has not been proved to be more efficient....
Use of misoprostol is associated with a higher risk of using other uterotonics (P<0.001). ...Combined use of misoprostol an …
Misoprostol in preventing postpartum hemorrhage: a meta-analysis.
Langenbach C. Langenbach C. Int J Gynaecol Obstet. 2006 Jan;92(1):10-8. doi: 10.1016/j.ijgo.2005.10.001. Epub 2005 Nov 23. Int J Gynaecol Obstet. 2006. PMID: 16309682 Review.
OBJECTIVE: To assess misoprostol's ability to prevent postpartum hemorrhage (PPH) where no alternatives exist. ...METHOD: Using the Mantel-Haenszel fixed-effects model and the DerSirmonian and Laird random-effects model, summary statistics indicated that misopros
OBJECTIVE: To assess misoprostol's ability to prevent postpartum hemorrhage (PPH) where no alternatives exist. ...METHOD: Usin …
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