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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1826 1
1829 2
1830 1
1847 1
1850 2
1851 2
1853 1
1866 1
1867 1
1869 1
1873 1
1875 1
1880 1
1882 1
1883 1
1885 1
1887 1
1889 5
1890 5
1891 5
1892 1
1893 2
1894 2
1895 3
1896 5
1897 6
1898 2
1899 1
1900 1
1901 1
1903 1
1904 1
1905 6
1906 3
1907 2
1908 1
1909 2
1910 3
1911 5
1912 2
1913 5
1914 1
1915 4
1916 3
1917 5
1918 2
1919 2
1920 1
1921 4
1923 3
1924 2
1925 1
1926 2
1927 1
1928 1
1929 2
1930 2
1933 5
1934 1
1935 2
1938 1
1939 4
1940 6
1942 1
1943 2
1944 5
1945 23
1946 24
1947 63
1948 73
1949 64
1950 91
1951 104
1952 92
1953 110
1954 145
1955 183
1956 159
1957 145
1958 134
1959 139
1960 130
1961 135
1962 150
1963 295
1964 405
1965 306
1966 297
1967 342
1968 427
1969 428
1970 502
1971 574
1972 695
1973 768
1974 709
1975 806
1976 800
1977 795
1978 843
1979 881
1980 967
1981 1026
1982 1193
1983 1199
1984 1243
1985 1269
1986 1241
1987 1128
1988 1135
1989 1189
1990 1221
1991 1228
1992 1220
1993 1265
1994 1261
1995 1282
1996 1309
1997 1302
1998 1315
1999 1202
2000 1393
2001 1361
2002 1303
2003 1465
2004 1490
2005 1657
2006 1674
2007 1627
2008 1723
2009 1705
2010 1749
2011 1827
2012 1900
2013 1942
2014 2121
2015 2058
2016 2090
2017 2154
2018 2240
2019 2484
2020 2836
2021 2846
2022 2739
2023 2482
2024 2250
2025 2303
2026 1561

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82,694 results

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Page 1
Morphine metabolites.
Christrup LL. Christrup LL. Acta Anaesthesiol Scand. 1997 Jan;41(1 Pt 2):116-22. doi: 10.1111/j.1399-6576.1997.tb04625.x. Acta Anaesthesiol Scand. 1997. PMID: 9061094 Review.
Morphine is a member of the morphinan-framed alkaloids, which are present in the poppy plant. The drug is soluble in water, but its solubility in lipids is poor. In man, morphine-3-glucuronide (M3G) and morphine-6-glucuronide (M6G) are the major metabolites o …
Morphine is a member of the morphinan-framed alkaloids, which are present in the poppy plant. The drug is soluble in water, but its s …
[Prescription of morphine].
Clausen TG, Lundstedt C. Clausen TG, et al. Ugeskr Laeger. 1997 Apr 14;159(16):2347. Ugeskr Laeger. 1997. PMID: 9163107 Danish. No abstract available.
A review of morphine and morphine-6-glucuronide's pharmacokinetic-pharmacodynamic relationships in experimental and clinical pain.
Sverrisdóttir E, Lund TM, Olesen AE, Drewes AM, Christrup LL, Kreilgaard M. Sverrisdóttir E, et al. Eur J Pharm Sci. 2015 Jul 10;74:45-62. doi: 10.1016/j.ejps.2015.03.020. Epub 2015 Apr 7. Eur J Pharm Sci. 2015. PMID: 25861720 Review.
Morphine is a widely used opioid for treatment of moderate to severe pain, but large interindividual variability in patient response and no clear guidance on how to optimise morphine dosage regimen complicates treatment strategy for clinicians. ...This review provid …
Morphine is a widely used opioid for treatment of moderate to severe pain, but large interindividual variability in patient response …
Forensic science.
Brettell TA, Saferstein R. Brettell TA, et al. Anal Chem. 1983 Apr;55(5):19R-31R. Anal Chem. 1983. PMID: 6346950 Review. No abstract available.
Metabolism and pharmacokinetics of morphine in neonates: A review.
Pacifici GM. Pacifici GM. Clinics (Sao Paulo). 2016 Aug;71(8):474-80. doi: 10.6061/clinics/2016(08)11. Clinics (Sao Paulo). 2016. PMID: 27626479 Free PMC article. Review.
Morphine is an agonist of the and k receptors, whose activation results in analgesia. ...The morphine-3-glucuronide metabolite has lower clearance, a shorter half-life and a smaller distribution volume compared with the morphine-6 metabolite, which is the m …
Morphine is an agonist of the and k receptors, whose activation results in analgesia. ...The morphine-3-glucuronide metaboli …
Morphine-6-glucuronide: morphine's successor for postoperative pain relief?
van Dorp EL, Romberg R, Sarton E, Bovill JG, Dahan A. van Dorp EL, et al. Anesth Analg. 2006 Jun;102(6):1789-97. doi: 10.1213/01.ane.0000217197.96784.c3. Anesth Analg. 2006. PMID: 16717327 Review.
In searching for an analgesic with fewer side effects than morphine, examination of morphine's active metabolite, morphine-6-glucuronide (M6G), suggests that M6G is possibly such a drug. ...In humans, M6G's potency is just half of that of morphine …
In searching for an analgesic with fewer side effects than morphine, examination of morphine's active metabolite, mo …
Biomedicine: Move over, morphine.
Crow JM. Crow JM. Nature. 2016 Jul 14;535(7611):S4-6. doi: 10.1038/535S4a. Nature. 2016. PMID: 27410530 No abstract available.
The role of morphine glucuronides in cancer pain.
Mercadante S. Mercadante S. Palliat Med. 1999 Mar;13(2):95-104. doi: 10.1191/026921699678158579. Palliat Med. 1999. PMID: 10474692 Review.
Morphine metabolites are involved in various ways in determining the complex effects of morphine, both favourable and adverse, and may complicate the clinical use of morphine in the treatment of cancer pain. The production and effects of the principal morp …
Morphine metabolites are involved in various ways in determining the complex effects of morphine, both favourable and adverse, …
3-Methoxynaltrexone, a selective heroin/morphine-6beta-glucuronide antagonist.
Brown GP, Yang K, King MA, Rossi GC, Leventhal L, Chang A, Pasternak GW. Brown GP, et al. FEBS Lett. 1997 Jul 21;412(1):35-8. doi: 10.1016/s0014-5793(97)00710-2. FEBS Lett. 1997. PMID: 9257684
Recent work has suggested that heroin and morphine-6beta-glucuronide (M6G) both act through a novel mu opioid receptor subtype distinct from those mediating morphine's actions. ...In vivo, 3-methoxynaltrexone (2.5 ng, i.c.v.) selectively antagonizes the analg …
Recent work has suggested that heroin and morphine-6beta-glucuronide (M6G) both act through a novel mu opioid receptor subtype distin …
82,694 results
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