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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1851 1
1868 1
1872 1
1873 1
1879 1
1882 1
1883 2
1891 1
1898 1
1905 1
1906 1
1907 1
1908 1
1909 3
1913 1
1914 1
1915 1
1917 1
1918 1
1919 2
1920 2
1922 1
1923 3
1924 3
1925 2
1926 1
1927 2
1928 2
1929 1
1934 1
1935 2
1938 1
1939 1
1940 1
1941 1
1942 1
1943 3
1945 12
1946 12
1947 25
1948 27
1949 23
1950 23
1951 30
1952 36
1953 41
1954 44
1955 42
1956 40
1957 35
1958 48
1959 51
1960 66
1961 56
1962 71
1963 112
1964 169
1965 139
1966 153
1967 185
1968 231
1969 219
1970 219
1971 234
1972 282
1973 255
1974 246
1975 213
1976 233
1977 233
1978 215
1979 215
1980 259
1981 224
1982 275
1983 296
1984 332
1985 352
1986 403
1987 424
1988 478
1989 550
1990 521
1991 572
1992 604
1993 640
1994 689
1995 666
1996 665
1997 751
1998 781
1999 888
2000 927
2001 969
2002 1027
2003 1199
2004 1312
2005 1463
2006 1560
2007 1701
2008 1814
2009 1794
2010 1841
2011 1968
2012 2224
2013 2301
2014 2619
2015 2866
2016 2927
2017 2629
2018 2819
2019 3084
2020 3699
2021 3534
2022 3438
2023 3200
2024 3248
2025 3588
2026 490

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66,961 results

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Page 1
Nicotine: From Discovery to Biological Effects.
Sansone L, Milani F, Fabrizi R, Belli M, Cristina M, Zagà V, de Iure A, Cicconi L, Bonassi S, Russo P. Sansone L, et al. Int J Mol Sci. 2023 Sep 26;24(19):14570. doi: 10.3390/ijms241914570. Int J Mol Sci. 2023. PMID: 37834017 Free PMC article. Review.
Nicotine, the primary psychoactive agent in tobacco leaves, has led to the widespread use of tobacco, with over one billion smokers globally. ...Understanding nicotine's complex biological effects is essential for comprehensive research and informed health po …
Nicotine, the primary psychoactive agent in tobacco leaves, has led to the widespread use of tobacco, with over one billion smokers g …
Nicotine's effect on cognition, a friend or foe?
Wang Q, Du W, Wang H, Geng P, Sun Y, Zhang J, Wang W, Jin X. Wang Q, et al. Prog Neuropsychopharmacol Biol Psychiatry. 2023 Jun 8;124:110723. doi: 10.1016/j.pnpbp.2023.110723. Epub 2023 Feb 1. Prog Neuropsychopharmacol Biol Psychiatry. 2023. PMID: 36736944 Review.
The possible mechanism underlying nicotine's effect is also explored. Finally, nicotine's detrimental effect on cognition is discussed, including in the prenatal and adolescent periods, and high-dose nicotine- and withdrawal-induced memory impai …
The possible mechanism underlying nicotine's effect is also explored. Finally, nicotine's detrimental effect on …
Cognitive Effects of Nicotine: Recent Progress.
Valentine G, Sofuoglu M. Valentine G, et al. Curr Neuropharmacol. 2018;16(4):403-414. doi: 10.2174/1570159X15666171103152136. Curr Neuropharmacol. 2018. PMID: 29110618 Free PMC article. Review.
METHODS: We provide a selective overview of recent advances in understanding nicotine's effects on cognitive function, a discussion of the role of cognitive function in vulnerability to TUD, followed by an overview of the neurobiological mechanisms underlying the co …
METHODS: We provide a selective overview of recent advances in understanding nicotine's effects on cognitive function, a discu …
E-cigarettes, nicotine, the lung and the brain: multi-level cascading pathophysiology.
Herman M, Tarran R. Herman M, et al. J Physiol. 2020 Nov;598(22):5063-5071. doi: 10.1113/JP278388. Epub 2020 Jul 6. J Physiol. 2020. PMID: 32515030 Free PMC article. Review.
In this review, we have compared and contrasted what is known regarding the effects of nicotine on the lungs vs. the effects of nicotine in the brain in the context of addiction. ...Nicotine's reinforcing properties are primarily mediated by activation …
In this review, we have compared and contrasted what is known regarding the effects of nicotine on the lungs vs. the effects of ni …
Anhedonia in Nicotine Dependence.
Gilbert DG, Stone BM. Gilbert DG, et al. Curr Top Behav Neurosci. 2022;58:167-184. doi: 10.1007/7854_2022_320. Curr Top Behav Neurosci. 2022. PMID: 35507287 Review.
A report by the national advisory mental health council workgroup on changes to the research domain criteria matrix, 2018) and the Situation x Trait Affective Response (STAR) model of nicotine's effects and nicotine dependence (Gilbert, Smoking individual dif …
A report by the national advisory mental health council workgroup on changes to the research domain criteria matrix, 2018) and the Situation …
The Role of Pharmacogenetics in Smoking.
El-Boraie A, Tyndale RF. El-Boraie A, et al. Clin Pharmacol Ther. 2021 Sep;110(3):599-606. doi: 10.1002/cpt.2345. Epub 2021 Jul 17. Clin Pharmacol Ther. 2021. PMID: 34165800 Review.
Candidate gene studies of smoking phenotypes have identified several pharmacogenes implicated in nicotine's pharmacokinetics (CYP2A6, CYP2B6, CYP2A13, FMOs, UGTs, and OCT2), and nicotine's pharmacodynamic response in the central nervous system (nicotin …
Candidate gene studies of smoking phenotypes have identified several pharmacogenes implicated in nicotine's pharmacokinetics ( …
Stimulus functions of nicotine.
LeSage MG. LeSage MG. Adv Pharmacol. 2022;93:133-170. doi: 10.1016/bs.apha.2021.11.001. Epub 2022 Jan 12. Adv Pharmacol. 2022. PMID: 35341565 Free PMC article.
The purpose of this chapter is to provide an overview of research that illustrates the respondent and operant stimulus functions of nicotine, using a contemporary taxonomy of stimulus functions as a general framework. Each function is formally defined and examples from res …
The purpose of this chapter is to provide an overview of research that illustrates the respondent and operant stimulus functions of nicot …
Meta-Analysis on Nicotine's Modulation of HIV-Associated Dementia.
Krishnan V, Vigorito M, Kota NK, Chang SL. Krishnan V, et al. J Neuroimmune Pharmacol. 2022 Dec;17(3-4):487-502. doi: 10.1007/s11481-021-10027-2. Epub 2021 Nov 10. J Neuroimmune Pharmacol. 2022. PMID: 34757527 Free PMC article.
Our study utilized QIAGEN Ingenuity Pathway Analysis (IPA) to identify and analyze molecular profiles and pathways underlying nicotine's impact on HAD pathology. The Qiagen Knowledge Base (QKB) defines HAD as "Dementia associated with acquired immunodeficiency syndr …
Our study utilized QIAGEN Ingenuity Pathway Analysis (IPA) to identify and analyze molecular profiles and pathways underlying nicotine …
Translational Research in Nicotine Addiction.
Fisher ML, Pauly JR, Froeliger B, Turner JR. Fisher ML, et al. Cold Spring Harb Perspect Med. 2021 Jun 1;11(6):a039776. doi: 10.1101/cshperspect.a039776. Cold Spring Harb Perspect Med. 2021. PMID: 32513669 Free PMC article. Review.
Therefore, the primary goal of preclinical research has been to further the understanding of the neural substrates and genetic influences involved in nicotine's effects and reassess potential drug targets. Pronounced advances have been made by investing in new trans …
Therefore, the primary goal of preclinical research has been to further the understanding of the neural substrates and genetic influences in …
Nicotine's Allure.
McGehee DS. McGehee DS. Neuron. 2009 Sep 10;63(5):564-5. doi: 10.1016/j.neuron.2009.08.029. Neuron. 2009. PMID: 19755099 Free article.
Both conscious and unconscious memory mechanisms contribute to the rewarding effects of nicotine and other drugs of abuse. In this issue of Neuron, Tang and Dani use in vivo measures of synaptic plasticity in freely moving mice to link nicotine-induced dopamine rele …
Both conscious and unconscious memory mechanisms contribute to the rewarding effects of nicotine and other drugs of abuse. In this is …
66,961 results
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