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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1966 4
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1968 7
1969 7
1970 7
1971 8
1972 2
1973 6
1974 3
1975 8
1976 7
1977 9
1978 8
1979 10
1980 13
1981 12
1982 17
1983 11
1984 19
1985 12
1986 12
1987 12
1988 18
1989 35
1990 31
1991 26
1992 15
1993 25
1994 21
1995 29
1996 25
1997 26
1998 25
1999 45
2000 55
2001 50
2002 44
2003 37
2004 41
2005 39
2006 45
2007 40
2008 28
2009 21
2010 20
2011 15
2012 17
2013 15
2014 15
2015 15
2016 15
2017 8
2018 5
2019 4
2020 10
2021 5
2022 8
2023 8
2024 10
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2026 4

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1,050 results

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Page 1
Linzagolix therapy versus a placebo in patients with endometriosis-associated pain: a prospective, randomized, double-blind, Phase 3 study (EDELWEISS 3).
Donnez J, Becker C, Taylor H, Carmona Herrera F, Donnez O, Horne A, Paszkowski M, Petraglia F, Renner SP, Patel A, Boolell M, Bestel E, Dolmans MM. Donnez J, et al. Hum Reprod. 2024 Jun 3;39(6):1208-1221. doi: 10.1093/humrep/deae076. Hum Reprod. 2024. PMID: 38648863 Free PMC article. Clinical Trial.
STUDY QUESTION: Does linzagolix administered orally once daily for up to 3 months at a dose of 75 mg alone or 200 mg in combination with add-back therapy (ABT) (1.0 mg estradiol; 0.5 mg norethindrone acetate, also known as norethisterone acetate [NETA]) demonstrate …
STUDY QUESTION: Does linzagolix administered orally once daily for up to 3 months at a dose of 75 mg alone or 200 mg in combination with add …
Impact of relugolix combination therapy on functioning and quality of life in women with endometriosis-associated pain.
As-Sanie S, Abrao MS, Reznichenko G, Wilk K, Zhong Y, Perry J, Hunsche E, Soulban G, Becker CM. As-Sanie S, et al. Fertil Steril. 2024 Oct;122(4):687-695. doi: 10.1016/j.fertnstert.2024.06.009. Epub 2024 Jun 19. Fertil Steril. 2024. PMID: 38906210 Free article. Clinical Trial.
OBJECTIVE: To evaluate the effect of relugolix combination therapy (relugolix CT; 40 mg relugolix, 1 mg estradiol, and 0.5 mg norethisterone acetate) for up to 2 years in the SPIRIT long-term extension study on functioning and health-related quality of life (QoL), using th …
OBJECTIVE: To evaluate the effect of relugolix combination therapy (relugolix CT; 40 mg relugolix, 1 mg estradiol, and 0.5 mg norethister …
Norethisterone for prolonged uterine bleeding associated with etonogestrel implant (IMPLANET): a randomized controlled trial.
Andrade MCR, Yamaguti EMM, de Nadai MN, Juliato CRT, Guazzelli CAF, Brito MB, Marcelino AC, Borges CS, Ragazini CS, Barbosa-Júnior F, Braga GC, Okano SHP, Poli-Neto OB, Vieira CS. Andrade MCR, et al. Am J Obstet Gynecol. 2026 Jan;234(1):101-115. doi: 10.1016/j.ajog.2025.08.029. Epub 2025 Aug 28. Am J Obstet Gynecol. 2026. PMID: 40885418 Free article. Clinical Trial.
OBJECTIVE: To evaluate the efficacy and safety of oral norethisterone acetate, also known as norethindrone acetate, at a dose of 10 mg/day for prolonged bleeding associated with etonogestrel implant use. ...Bleeding cessation using up to 14 pills was higher (91.1% v …
OBJECTIVE: To evaluate the efficacy and safety of oral norethisterone acetate, also known as norethindrone acetate, at a dose …
Menopausal therapy and endometrial pathology.
Craft I, Swinhoe J, Mugglestone CJ. Craft I, et al. Br Med J. 1978 Aug 5;2(6134):429-30. doi: 10.1136/bmj.2.6134.429-c. Br Med J. 1978. PMID: 687955 Free PMC article. Clinical Trial.
Small treatment groups received either 1) cyclical estradiol valerate 2 mg plus norgestrel .5 mg for 21 of 28 days; 2) continuous estradiol valerate 2 mg plus norgestrel .5 mg daily; 3) continuous estradiol valerate 1 mg twice daily plus levonorgestrel .25 mg daily; 4) cyclical e …
Small treatment groups received either 1) cyclical estradiol valerate 2 mg plus norgestrel .5 mg for 21 of 28 days; 2) continuous estradiol …
Linzagolix rapidly reduces heavy menstrual bleeding in women with uterine fibroids: an analysis of the PRIMROSE 1 and 2 trials.
Donnez J, Becker CM, Mangler M, Paszkowski M, Paszkowski T, St-Pierre J, Ionescu-Ittu R, Boolell M, Bestel E, Hori S, Petraglia F. Donnez J, et al. Fertil Steril. 2025 Jun;123(6):1093-1100. doi: 10.1016/j.fertnstert.2024.12.031. Epub 2025 Jan 3. Fertil Steril. 2025. PMID: 39755138 Free article. Clinical Trial.
Eligible participants were randomized equally across four treatment arms (linzagolix 100 mg and 200 mg, with and without concomitant hormonal add-back therapy [ABT] consisting of 1-mg estradiol and 0.5-mg norethisterone acetate) and one placebo arm. The cumulative incidenc …
Eligible participants were randomized equally across four treatment arms (linzagolix 100 mg and 200 mg, with and without concomitant hormona …
Linzagolix with and without hormonal add-back therapy for symptomatic uterine fibroids: PRIMROSE 1 & 2 long-term extension and withdrawal study.
Donnez J, Petraglia F, Taylor H, Becker CM, Becker S, Herrera FC, Bestel E, Hori S, Dolmans MM. Donnez J, et al. Fertil Steril. 2025 Oct;124(4):737-748. doi: 10.1016/j.fertnstert.2025.06.016. Epub 2025 Jun 19. Fertil Steril. 2025. PMID: 40543832 Free article. Clinical Trial.
OBJECTIVE: To evaluate whether oral linzagolix administered once daily for up to 52 weeks (extension study) at a dose of 100 mg or 200 mg with or without hormonal add-back therapy (ABT) (1.0 mg estradiol; 0.5 mg norethisterone acetate) can maintain the efficacy and tolerab …
OBJECTIVE: To evaluate whether oral linzagolix administered once daily for up to 52 weeks (extension study) at a dose of 100 mg or 200 mg wi …
Effect of ethinyl estradiol/norethisterone acetate with and without scaling on periodontal status and high-sensitivity C-reactive protein levels in women with polycystic ovary syndrome having gingivitis: a randomized controlled trial.
Verma R, Tewari S, Singhal SR, Sangwan A. Verma R, et al. Quintessence Int. 2024 Dec 11;55(10):792-802. doi: 10.3290/j.qi.b5751228. Quintessence Int. 2024. PMID: 39287093 Clinical Trial.
There is a dearth of literature addressing the effect of ethinyl estradiol/norethisterone acetate (EE/NETA) on gingival and systemic inflammation in these patients. This randomized trial aimed to evaluate the effect of EE/NETA with and without scaling on periodontium and h …
There is a dearth of literature addressing the effect of ethinyl estradiol/norethisterone acetate (EE/NETA) on gingival and systemic …
Estrogen treatment of excessively tall girls.
Zachmann M, Ferrandez A, Můrset G, Prader A. Zachmann M, et al. Helv Paediatr Acta. 1975 May;30(1):11-30. Helv Paediatr Acta. 1975. PMID: 169220 Clinical Trial.
40 excessively tall girls with a mean height prediction of 182 cm were treated for serious psychosocial reasons continuously with ethinylestradiol 0.3 mg daily and with norethisterone 10 mg daily for 5-7 days every 4th week. Their age at the start of treatment ranged from …
40 excessively tall girls with a mean height prediction of 182 cm were treated for serious psychosocial reasons continuously with ethinylest …
Effects of estradiol and norethisterone on lipids, insulin resistance and carotid flow.
Fernandes CE, Pompei LM, Machado RB, Ferreira JA, Melo NR, Peixoto S. Fernandes CE, et al. Maturitas. 2008 Mar 20;59(3):249-58. doi: 10.1016/j.maturitas.2008.02.001. Epub 2008 Mar 21. Maturitas. 2008. PMID: 18359175 Clinical Trial.
METHODS: A prospective, randomized, double-blind study was carried out in which 77 postmenopausal women received one of the three treatment regimens: (A) 2mg oral micronized estradiol (E2) (n=25); (B) 2mg oral E2+1mg oral norethisterone acetate (NETA) (n=28); or C) placebo …
METHODS: A prospective, randomized, double-blind study was carried out in which 77 postmenopausal women received one of the three treatment …
The role of hormone replacement therapy in endometrial polyp formation.
Oguz S, Sargin A, Kelekci S, Aytan H, Tapisiz OL, Mollamahmutoglu L. Oguz S, et al. Maturitas. 2005 Mar 14;50(3):231-6. doi: 10.1016/j.maturitas.2004.06.002. Maturitas. 2005. PMID: 15734604 Clinical Trial.
The first group received Premelle 2.5 mg (Group-I) (0.625 mg conjugated estrogen + 2.5 mg medroxyprogestorone), the second received Kliogest (Group-II) (2 mg estradiol + 1 mg norethisterone) and the last received Livial (Group-III) (2.5 mg tibolone) at least for 36 months …
The first group received Premelle 2.5 mg (Group-I) (0.625 mg conjugated estrogen + 2.5 mg medroxyprogestorone), the second received Kliogest …
1,050 results