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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1965 3
1966 5
1967 4
1968 10
1969 6
1970 4
1971 2
1972 6
1973 6
1974 8
1975 7
1976 9
1977 10
1978 16
1979 7
1980 8
1981 11
1982 10
1983 6
1984 8
1985 10
1986 12
1987 14
1988 7
1989 15
1990 9
1991 8
1992 11
1993 13
1994 10
1995 12
1996 16
1997 19
1998 20
1999 16
2000 16
2001 27
2002 16
2003 27
2004 11
2005 9
2006 15
2007 15
2008 10
2009 30
2010 14
2011 15
2012 9
2013 11
2014 10
2015 10
2016 4
2017 4
2018 4
2019 3
2020 3
2021 2
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574 results
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Page 1
Patient Assisted Intervention for Neuropathy: Comparison of Treatment in Real Life Situations (PAIN-CONTRoLS): Bayesian Adaptive Comparative Effectiveness Randomized Trial.
Barohn RJ, Gajewski B, Pasnoor M, Brown A, Herbelin LL, Kimminau KS, Mudaranthakam DP, Jawdat O, Dimachkie MM; Patient Assisted Intervention for Neuropathy: Comparison of Treatment in Real Life Situations (PAIN-CONTRoLS) Study Team, Iyadurai S, Stino A, Kissel J, Pascuzzi R, Brannagan T, Wicklund M, Ahmed A, Walk D, Smith G, Quan D, Heitzman D, Tobon A, Ladha S, Wolfe G, Pulley M, Hayat G, Li Y, Thaisetthawatkul P, Lewis R, Biliciler S, Sharma K, Salajegheh K, Trivedi J, Mallonee W, Burns T, Jacoby M, Bril V, Vu T, Ramchandren S, Bazant M, Austin S, Karam C, Hussain Y, Kutz C, Twydell P, Scelsa S, Kushlaf H, Wymer J, Hehir M, Kolb N, Ralph J, Barboi A, Verma N, Ahmed M, Memon A, Saperstein D, Lou JS, Swenson A, Cash T. Barohn RJ, et al. JAMA Neurol. 2021 Jan 1;78(1):68-76. doi: 10.1001/jamaneurol.2020.2590. JAMA Neurol. 2021. PMID: 32809014 Free PMC article. Clinical Trial.
OBJECTIVE: To determine which medication (pregabalin, duloxetine, nortriptyline, or mexiletine) is most effective for reducing neuropathic pain and best tolerated in patients with CSPN. ...The probability each medication yielded the highest utility was 0.52 for nortript
OBJECTIVE: To determine which medication (pregabalin, duloxetine, nortriptyline, or mexiletine) is most effective for reducing neurop …
Nortriptyline and gabapentin, alone and in combination for neuropathic pain: a double-blind, randomised controlled crossover trial.
Gilron I, Bailey JM, Tu D, Holden RR, Jackson AC, Houlden RL. Gilron I, et al. Lancet. 2009 Oct 10;374(9697):1252-61. doi: 10.1016/S0140-6736(09)61081-3. Epub 2009 Sep 30. Lancet. 2009. PMID: 19796802 Clinical Trial.
Mean daily pain (0-10; numerical rating scale) was 5.4 (95% CI 5.0 to 5.8) at baseline, and at maximum tolerated dose, pain was 3.2 (2.5 to 3.8) for gabapentin, 2.9 (2.4 to 3.4) for nortriptyline, and 2.3 (1.8 to 2.8) for combination treatment. Pain with combination treatm …
Mean daily pain (0-10; numerical rating scale) was 5.4 (95% CI 5.0 to 5.8) at baseline, and at maximum tolerated dose, pain was 3.2 (2.5 to …
Efficacy and safety of nortriptyline in functional dyspepsia in Asians: A randomized double-blind placebo-controlled trial.
Kaosombatwattana U, Pongprasobchai S, Limsrivilai J, Maneerattanaporn M, Leelakusolvong S, Tanwandee T. Kaosombatwattana U, et al. J Gastroenterol Hepatol. 2018 Feb;33(2):411-417. doi: 10.1111/jgh.13914. J Gastroenterol Hepatol. 2018. PMID: 28768370 Clinical Trial.
Eight and seven patients in nortriptyline and placebo groups were lost to follow up. Seven patients withdrew due to mild adverse events (nortriptyline 1 and placebo 6). Overall, 19 with nortriptyline and 20 with placebo completed the study. Patients receiving …
Eight and seven patients in nortriptyline and placebo groups were lost to follow up. Seven patients withdrew due to mild adverse even …
Suicidal ideation during treatment of depression with escitalopram and nortriptyline in genome-based therapeutic drugs for depression (GENDEP): a clinical trial.
Perroud N, Uher R, Marusic A, Rietschel M, Mors O, Henigsberg N, Hauser J, Maier W, Souery D, Placentino A, Szczepankiewicz A, Jorgensen L, Strohmaier J, Zobel A, Giovannini C, Elkin A, Gunasinghe C, Gray J, Campbell D, Gupta B, Farmer AE, McGuffin P, Aitchison KJ. Perroud N, et al. BMC Med. 2009 Oct 15;7:60. doi: 10.1186/1741-7015-7-60. BMC Med. 2009. PMID: 19832967 Free PMC article. Clinical Trial.
Severity of depression predicted TESI and TWOSI. In men, nortriptyline was associated with a 9.8-fold and 2.4-fold increase in TESI and TWOSI compared to escitalopram, respectively. ...In men, treatment with escitalopram is associated with lower risk of suicidal ideation c …
Severity of depression predicted TESI and TWOSI. In men, nortriptyline was associated with a 9.8-fold and 2.4-fold increase in TESI a …
The clinical efficacy and side-effects of mianserin and nortriptyline in depressed out-patients: a double-blind randomized trial.
Hoc J. Hoc J. Curr Med Res Opin. 1982;8(4):282-9. doi: 10.1185/03007998209109779. Curr Med Res Opin. 1982. PMID: 6759061 Clinical Trial.
A double-blind randomized study was performed in 86 depressed out-patients, in order to compare the efficacy and tolerance of mianserin (30 to 60 mg daily) with that of nortriptyline (75 to 150 mg daily). Both drugs were administered for 6 weeks after a wash-out period of …
A double-blind randomized study was performed in 86 depressed out-patients, in order to compare the efficacy and tolerance of mianserin (30 …
A controlled trial of nortriptyline, sustained-release bupropion and placebo for smoking cessation: preliminary results.
Haggsträm FM, Chatkin JM, Sussenbach-Vaz E, Cesari DH, Fam CF, Fritscher CC. Haggsträm FM, et al. Pulm Pharmacol Ther. 2006;19(3):205-9. doi: 10.1016/j.pupt.2005.05.003. Epub 2006 Mar 6. Pulm Pharmacol Ther. 2006. PMID: 16517193 Clinical Trial.
The odds ratio was not statistically different for smokers using nortriptyline or bupropion (OR 1.60; 95% CI 0.66-3.86; p = 0.35). The most common adverse events were dry mouth and drowsiness in the nortriptyline group and dry mouth and insomnia in the bupropion gro …
The odds ratio was not statistically different for smokers using nortriptyline or bupropion (OR 1.60; 95% CI 0.66-3.86; p = 0.35). Th …
Effect of nortriptyline on brain responses to painful esophageal acid infusion in patients with non-erosive reflux disease.
Forcelini CM, Tomiozzo JC Jr, Farré R, Van Oudenhove L, Callegari-Jacques SM, Ribeiro M, Madalosso BH, Fornari F. Forcelini CM, et al. Neurogastroenterol Motil. 2014 Feb;26(2):187-95. doi: 10.1111/nmo.12251. Epub 2013 Nov 4. Neurogastroenterol Motil. 2014. PMID: 24188252 Clinical Trial.
Antidepressants might help to relieve heartburn by acting on the esophagus-brain axis. We aimed to assess the effect of nortriptyline on behavioral and brain responses to painful esophageal acid infusion in NERD patients evaluated with functional magnetic resonance imaging …
Antidepressants might help to relieve heartburn by acting on the esophagus-brain axis. We aimed to assess the effect of nortriptyline
Clinical response and plasma concentration of amitriptyline and its metabolite nortriptyline.
Vandel S, Vandel B, Sandoz M, Allers G, Bechtel P, Volmat R. Vandel S, et al. Eur J Clin Pharmacol. 1978 Nov 27;14(3):185-90. doi: 10.1007/BF02089958. Eur J Clin Pharmacol. 1978. PMID: 365538 Clinical Trial.
Plasma levels of amitriptyline and nortriptyline were measured twice weekly in 62 patients treated for three weeks with i.m. amitriptyline 120 mg/day. ...The plasma level of amitriptyline plus nortriptyline must lie between 60 to 220 ng/ml, and that of nortriptyl
Plasma levels of amitriptyline and nortriptyline were measured twice weekly in 62 patients treated for three weeks with i.m. amitript …
Gabapentin versus nortriptyline in post-herpetic neuralgia patients: a randomized, double-blind clinical trial--the GONIP Trial.
Chandra K, Shafiq N, Pandhi P, Gupta S, Malhotra S. Chandra K, et al. Int J Clin Pharmacol Ther. 2006 Aug;44(8):358-63. doi: 10.5414/cpp44358. Int J Clin Pharmacol Ther. 2006. PMID: 16961166 Clinical Trial.
BACKGROUND: Gabapentin and nortriptyline have not been compared in a randomized trial in post-herpetic neuralgia (PHN). ...Gabapentin was, however, better tolerated as compared to nortriptyline. CONCLUSION: Gabapentin was shown to be equally efficacious but was bett …
BACKGROUND: Gabapentin and nortriptyline have not been compared in a randomized trial in post-herpetic neuralgia (PHN). ...Gabapentin …
Estimating dose-response for time to remission with instrumental variable adjustment: the obscuring effects of drug titration in Genome Based Therapeutic Drugs for Depression Trial (GENDEP): clinical trial data.
Hellier J, Emsley R, Pickles A. Hellier J, et al. Trials. 2020 Jan 3;21(1):10. doi: 10.1186/s13063-019-3810-9. Trials. 2020. PMID: 31900198 Free PMC article. Clinical Trial.
METHOD: Weekly antidepressant dose was measured in 380 men and women with major depression treated with escitalopram or nortriptyline for 12 weeks as part of the Genome Based Therapeutic Drugs for Depression (GENDEP) study. ...
METHOD: Weekly antidepressant dose was measured in 380 men and women with major depression treated with escitalopram or nortriptyline
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