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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1984 5
1985 2
1986 23
1987 29
1988 21
1989 33
1990 41
1991 53
1992 35
1993 31
1994 40
1995 45
1996 47
1997 32
1998 40
1999 43
2000 39
2001 35
2002 32
2003 42
2004 50
2005 45
2006 56
2007 55
2008 50
2009 40
2010 35
2011 43
2012 50
2013 52
2014 29
2015 41
2016 34
2017 41
2018 25
2019 22
2020 27
2021 23
2022 17
2023 23
2024 20
2025 19

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1,396 results

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Page 1
A multicentre, randomised, double-blind, double-dummy, parallel-controlled, phase 3 clinical trial assessing the efficacy and safety of intravenous nemonoxacin malate vs. levofloxacin for community-acquired pneumonia in adult patients.
Li Y, Zhu D, Sun S, Chang X, Cao Z, Yang Y, Fu X, Li X, Xu J, Zhu Y, Hui F, Xu X, Chen Z, Peng L, Ma Z, Mo B, Li C, Lv Y, Zhao L, Zhu G, He Y, Liu H, Chen J, Wang Y, Liang Y, Lu Y, Qin Z, Yang H, Zhang M, Wu S, Tong Z, Ye F, Xiao Z, Wang X, Qiu C, Kuang J, Huang H, Wang K, Ying K, Jin F, Lv X, Huang Y, Liu D, Wang W, Zhang Y. Li Y, et al. Int J Antimicrob Agents. 2024 Aug;64(2):107235. doi: 10.1016/j.ijantimicag.2024.107235. Epub 2024 Jun 6. Int J Antimicrob Agents. 2024. PMID: 38851462 Free article. Clinical Trial.
Secondary efficacy and safety were also compared between nemonoxacin and levofloxacin. RESULTS: Overall, 525 patients were randomised and treated with nemonoxacin (n = 349) or levofloxacin (n = 176). The clinical cure rate was 91.8% (279/304) for nemonoxacin and 85. …
Secondary efficacy and safety were also compared between nemonoxacin and levofloxacin. RESULTS: Overall, 525 patients were randomised …
Efficacy and Safety of Higher Doses of Levofloxacin for Multidrug-resistant Tuberculosis: A Randomized, Placebo-controlled Phase II Clinical Trial.
Phillips PPJ, Peloquin CA, Sterling TR, Kaur P, Diacon AH, Gotuzzo E, Benator D, Warren RM, Sikes D, Lecca L, Gandhi NR, Streicher EM, Dianis N, Eisenach K, Mitnick CD, Horsburgh CR Jr. Phillips PPJ, et al. Am J Respir Crit Care Med. 2025 Jul;211(7):1277-1287. doi: 10.1164/rccm.202407-1354OC. Am J Respir Crit Care Med. 2025. PMID: 40080768 Free PMC article. Clinical Trial.
Objective: To determine the dose of levofloxacin needed to achieve maximal efficacy and acceptable safety and tolerability as part of a multidrug TB regimen. ...Conclusions: As part of a multidrug regimen, doses of levofloxacin >1,000 mg/d resulted in greater exp …
Objective: To determine the dose of levofloxacin needed to achieve maximal efficacy and acceptable safety and tolerability as part of …
Levofloxacin prophylaxis to prevent bacterial infection in chemotherapy-induced neutropenia in acute leukemia.
Rahman MM, Khan MA. Rahman MM, et al. Bangladesh Med Res Counc Bull. 2009 Dec;35(3):91-4. doi: 10.3329/bmrcb.v35i3.4130. Bangladesh Med Res Counc Bull. 2009. PMID: 20922911 Clinical Trial.
This study assessed the efficacy of prophylaxis with oral levofloxacin in chemotherapy-induced febrile neutropenic patients. Eighty patients of acute leukemia was randomly assigned to had levofoxacin (500 mg/daily) or placebo from the starting of chemotherapy. ...The numbe …
This study assessed the efficacy of prophylaxis with oral levofloxacin in chemotherapy-induced febrile neutropenic patients. Eighty p …
Levofloxacin to prevent bacterial infection in patients with cancer and neutropenia.
Bucaneve G, Micozzi A, Menichetti F, Martino P, Dionisi MS, Martinelli G, Allione B, D'Antonio D, Buelli M, Nosari AM, Cilloni D, Zuffa E, Cantaffa R, Specchia G, Amadori S, Fabbiano F, Deliliers GL, Lauria F, Foà R, Del Favero A; Gruppo Italiano Malattie Ematologiche dell'Adulto (GIMEMA) Infection Program. Bucaneve G, et al. N Engl J Med. 2005 Sep 8;353(10):977-87. doi: 10.1056/NEJMoa044097. N Engl J Med. 2005. PMID: 16148283 Free article. Clinical Trial.
METHODS: We randomly assigned 760 consecutive adult patients with cancer in whom chemotherapy-induced neutropenia (<1000 neutrophils per cubic millimeter) was expected to occur for more than seven days to receive either oral levofloxacin (500 mg daily) or placebo from t …
METHODS: We randomly assigned 760 consecutive adult patients with cancer in whom chemotherapy-induced neutropenia (<1000 neutrophils per …
Ocular penetration of levofloxacin, ofloxacin and ciprofloxacin in eyes with functioning filtering blebs: investigator masked, randomised clinical trial.
Cantor LB, WuDunn D, Yung CW, Valluri S, Catoira YP, Hoop JS, Morgan LS. Cantor LB, et al. Br J Ophthalmol. 2008 Mar;92(3):345-7. doi: 10.1136/bjo.2007.121541. Epub 2008 Jan 22. Br J Ophthalmol. 2008. PMID: 18211932 Clinical Trial.
BACKGROUND/AIMS: To compare the penetration of levofloxacin, ofloxacin and ciprofloxacin in the aqueous humour of eyes with functioning filtering blebs. ...CONCLUSIONS: Topical levofloxacin penetrates better than ofloxacin or ciprofloxacin into the aqu …
BACKGROUND/AIMS: To compare the penetration of levofloxacin, ofloxacin and ciprofloxacin in the aqueous humour of eyes with fu …
A randomized, active-controlled, multicentre clinical trial to evaluate the efficacy and safety of oral sitafloxacin versus levofloxacin in Chinese adults with acute uncomplicated or complicated urinary tract infection.
Li Y, Yin Y, Peng X, Zheng H, Fu F, Liu Z, Wu X, Wu X, Zheng S, Chen N, He L, Ren L, Ni Z, Li D, Liang P, Lv X, Zhang Y. Li Y, et al. Ann Med. 2021 Dec;53(1):217-226. doi: 10.1080/07853890.2020.1861322. Ann Med. 2021. PMID: 33331182 Free PMC article. Clinical Trial.
METHODS: In this randomized, active-controlled clinical trial, the patients with acute uncomplicated UTI were randomized to receive sitafloxacin 100-mg once-daily (qd) or levofloxacin 500-mg qd orally for 3-5 days. The patients with complicated UTI were randomized to recei …
METHODS: In this randomized, active-controlled clinical trial, the patients with acute uncomplicated UTI were randomized to receive sitaflox …
Ciprofloxacin versus levofloxacin prophylaxis in hematopoietic stem cell transplantation: A randomized trial.
Farhan S, Mazur I, Hartzell S, Xie P, Neme K, German A, Mikulandric N, Patel K, Wu M, Kortam N, Yaseen A, Sweidan A, Latack K, Emole J, Peres E, Abidi MH, Ramesh M. Farhan S, et al. Int J Infect Dis. 2024 Oct;147:107172. doi: 10.1016/j.ijid.2024.107172. Epub 2024 Jul 15. Int J Infect Dis. 2024. PMID: 39019103 Free article. Clinical Trial.
RESULTS: Between June 4, 2018, and May 23, 2022, we randomly assigned 308 consecutive patients to receive ciprofloxacin (154 patients) or levofloxacin (154 patients). BSI was similar in both the ciprofloxacin and levofloxacin groups (18 [11.7%] vs 18 [11.7%]). Pneum …
RESULTS: Between June 4, 2018, and May 23, 2022, we randomly assigned 308 consecutive patients to receive ciprofloxacin (154 patients) or …
Comparison of the prophylactic effect of cefazolin injection versus oral levofloxacin as prophylactic antibiotic in TURP surgery: a randomized clinical trial.
Haghighi R, Kameli A, Razi A, Abroon D, Amani A. Haghighi R, et al. BMC Pharmacol Toxicol. 2024 Dec 2;25(1):91. doi: 10.1186/s40360-024-00814-x. BMC Pharmacol Toxicol. 2024. PMID: 39623434 Free PMC article. Clinical Trial.
METHODS: In an analytical-comparative trial, the participants were randomly divided into two groups to receive cefazolin or levofloxacin before the surgery. RESULTS: The duration of surgery (min) and catheterization (days) were 41.5 11.7 and 4.7 1.8 for levofloxacin …
METHODS: In an analytical-comparative trial, the participants were randomly divided into two groups to receive cefazolin or levofloxacin …
The effect of povidone-iodine 10% plus levofloxacin 0.5% before cataract surgery: a randomized clinical trial.
Azimi A, Jafari MR, Namvar E, Masihpour N, Meshksar S. Azimi A, et al. BMC Res Notes. 2025 Mar 18;18(1):116. doi: 10.1186/s13104-025-07116-3. BMC Res Notes. 2025. PMID: 40102985 Free PMC article. Clinical Trial.
This study was designed to assess the efficacy of using povidone-iodine (PVI) 10% and levofloxacin 0.5% about one hour before cataract surgery in minimizing aqueous contamination compared with using PVI 10%. The intervention group received three drops of mixed povidone-iod …
This study was designed to assess the efficacy of using povidone-iodine (PVI) 10% and levofloxacin 0.5% about one hour before catarac …
A non-randomized pragmatic historically controlled trial evaluating the effectiveness and safety of a bedaquiline or a linezolid-based short regimen for rifampicin-resistant tuberculosis.
Martínez-Campreciós J, Aznar ML, Zacarias A, Terán R, Nindia A, Espinosa-Pereiro J, Aixut S, Ramos ME, Nicolau MJ, Sulleiro E, Tórtola MT, Sánchez-Montalvá A, Molina I. Martínez-Campreciós J, et al. J Infect. 2024 Dec;89(6):106291. doi: 10.1016/j.jinf.2024.106291. Epub 2024 Oct 18. J Infect. 2024. PMID: 39426632 Free article. Clinical Trial.
The strategy assigned participants to receive a bedaquiline (BDQ) or a linezolid-based (LZF) regimen supplemented with levofloxacin, clofazimine, and cycloserine for up to 9 months. RESULTS: One hundred and twenty-one participants with pulmonary RR-TB were treated with the …
The strategy assigned participants to receive a bedaquiline (BDQ) or a linezolid-based (LZF) regimen supplemented with levofloxacin, …
1,396 results