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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1981 1
1982 2
1983 22
1984 57
1985 67
1986 95
1987 78
1988 126
1989 174
1990 207
1991 248
1992 306
1993 273
1994 372
1995 507
1996 494
1997 472
1998 512
1999 564
2000 483
2001 521
2002 555
2003 517
2004 458
2005 609
2006 464
2007 365
2008 350
2009 353
2010 417
2011 380
2012 394
2013 376
2014 388
2015 446
2016 406
2017 376
2018 356
2019 355
2020 407
2021 389
2022 402
2023 356
2024 384
2025 431
2026 101

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14,666 results

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Page 1
Proton Pump Inhibitors and Bone Health: An Update Narrative Review.
Lespessailles E, Toumi H. Lespessailles E, et al. Int J Mol Sci. 2022 Sep 14;23(18):10733. doi: 10.3390/ijms231810733. Int J Mol Sci. 2022. PMID: 36142643 Free PMC article. Review.
As of 2015, the FDA has already approved six drugs of this class (omeprazole, esomeprazole, lansoprazole, dexlansoprazole, pantoprazole and rabeprazole). Recently, the risks and benefits of long-term PPI use were questioned and many studies indicated that their use …
As of 2015, the FDA has already approved six drugs of this class (omeprazole, esomeprazole, lansoprazole, dexlansoprazole, pan …
Pharmacological treatment of gastro-oesophageal reflux in children.
Tighe MP, Andrews E, Liddicoat I, Afzal NA, Hayen A, Beattie RM. Tighe MP, et al. Cochrane Database Syst Rev. 2023 Aug 22;8(8):CD008550. doi: 10.1002/14651858.CD008550.pub3. Cochrane Database Syst Rev. 2023. PMID: 37635269 Free PMC article.
Omeprazole versus ranitidine: one study (76 infants; very low-certainty evidence) showed omeprazole may or may not provide symptomatic benefit equivalent to ranitidine. ...If a medication is required, there is no clear evidence based on summary data for omeprazol
Omeprazole versus ranitidine: one study (76 infants; very low-certainty evidence) showed omeprazole may or may not provide sym
An update on drug-drug interactions associated with proton pump inhibitors.
Ben Ghezala I, Luu M, Bardou M. Ben Ghezala I, et al. Expert Opin Drug Metab Toxicol. 2022 May;18(5):337-346. doi: 10.1080/17425255.2022.2098107. Epub 2022 Jul 11. Expert Opin Drug Metab Toxicol. 2022. PMID: 35787720 Review.
Interestingly, not all PPIs have the same pharmacokinetic and pharmacodynamic profile, with some having a strong potential to inhibit CYP2C19, such as omeprazole, esomeprazole, and lansoprazole, while others, pantoprazole, rabeprazole, and dexlansoprazole, are weak …
Interestingly, not all PPIs have the same pharmacokinetic and pharmacodynamic profile, with some having a strong potential to inhibit CYP2C1 …
Comparative effectiveness and tolerability of esomeprazole and omeprazole in gastro-esophageal reflux disease: A systematic review and meta-analysis.
Qi Q, Wang R, Liu L, Zhao F, Wang S. Qi Q, et al. Int J Clin Pharmacol Ther. 2015 Oct;53(10):803-10. doi: 10.5414/CP202396. Int J Clin Pharmacol Ther. 2015. PMID: 26329348
These results revealed a significant difference between esomeprazole vs. omeprazole (RR=1.06, 95% CI [1.01, 1.10], I2=72%, p=0.01) by subgroup according to dosage by random effects model, and a significant difference between esomeprazole 40 mg vs. omeprazo
These results revealed a significant difference between esomeprazole vs. omeprazole (RR=1.06, 95% CI [1.01, 1.10], I2=72%, p=0 …
Esomeprazole.
Spencer CM, Faulds D. Spencer CM, et al. Drugs. 2000 Aug;60(2):321-9; discussion 330-1. doi: 10.2165/00003495-200060020-00006. Drugs. 2000. PMID: 10983736 Review.
Esomeprazole, a new proton pump inhibitor, is the S-isomer of omeprazole and is the first such inhibitor to be developed as a single isomer. ...Esomeprazole-based triple therapy for 7 days was as effective for eradication of Helicobacter pylori as longer o
Esomeprazole, a new proton pump inhibitor, is the S-isomer of omeprazole and is the first such inhibitor to be developed as a
Gastric acid control with esomeprazole, lansoprazole, omeprazole, pantoprazole, and rabeprazole: a five-way crossover study.
Miner P Jr, Katz PO, Chen Y, Sostek M. Miner P Jr, et al. Am J Gastroenterol. 2003 Dec;98(12):2616-20. doi: 10.1111/j.1572-0241.2003.08783.x. Am J Gastroenterol. 2003. PMID: 14687806 Clinical Trial.
The objective of this study was to evaluate and compare intragastric pH following standard doses of esomeprazole, lansoprazole, omeprazole, pantoprazole and rabeprazole. METHODS: This randomized, open-label, comparative five-way crossover study evaluated the 24-h in …
The objective of this study was to evaluate and compare intragastric pH following standard doses of esomeprazole, lansoprazole, om
Efficacy and safety of esomeprazole compared with omeprazole in GERD patients with erosive esophagitis: a randomized controlled trial.
Richter JE, Kahrilas PJ, Johanson J, Maton P, Breiter JR, Hwang C, Marino V, Hamelin B, Levine JG; Esomeprazole Study Investigators. Richter JE, et al. Am J Gastroenterol. 2001 Mar;96(3):656-65. doi: 10.1111/j.1572-0241.2001.3600_b.x. Am J Gastroenterol. 2001. PMID: 11280530 Clinical Trial.
Healing rates at wk 4 were 81.7% and 68.7%, respectively. Esomeprazole was superior to omeprazole for all secondary measures and had a similar safety profile. ...The tolerability and safety of esomeprazole are comparable to that of omeprazole. (Am...
Healing rates at wk 4 were 81.7% and 68.7%, respectively. Esomeprazole was superior to omeprazole for all secondary measures a …
Naproxen/esomeprazole (Vimovo).
[No authors listed] [No authors listed] Med Lett Drugs Ther. 2010 Sep 20;52(1347):74-5. Med Lett Drugs Ther. 2010. PMID: 20847717 No abstract available.
Intravenous esomeprazole.
Keating GM, Figgitt DP. Keating GM, et al. Drugs. 2004;64(8):875-82; discussion 883. doi: 10.2165/00003495-200464080-00008. Drugs. 2004. PMID: 15059043
The proton pump inhibitor esomeprazole comprises the S-isomer of omeprazole. An intravenous formulation of the drug has been developed for use in patients not able to take oral drugs. ...In addition, control of basal and pentagastrin-stimulated gastric acid secretio …
The proton pump inhibitor esomeprazole comprises the S-isomer of omeprazole. An intravenous formulation of the drug has been d …
Addendum: Dexlansoprazole for GERD.
[No authors listed] [No authors listed] Med Lett Drugs Ther. 2022 May 16;64(1650):79-80. Med Lett Drugs Ther. 2022. PMID: 35536912 No abstract available.
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