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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1965 6
1966 3
1968 2
1970 2
1971 5
1972 1
1973 1
1975 2
1976 6
1977 2
1978 1
1979 3
1980 1
1981 1
1982 1
1983 4
1986 5
1987 1
1988 2
1990 2
1993 2
1994 1
1995 1
1997 2
2001 1
2003 1
2004 2
2005 1
2006 1
2008 1
2010 1
2012 1
2014 1
2017 1
2018 1
2020 2
2022 3
2023 2
2024 2
2025 0

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76 results

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Page 1
A controlled clinical trial of chlormezanone, orphenadrine, orphenadrine/paracetamol and placebo in the treatment of painful skeletal muscle spasms.
Valtonen EJ. Valtonen EJ. Ann Clin Res. 1975 Apr;7(2):85-8. Ann Clin Res. 1975. PMID: 1103709 Clinical Trial.
Four hundred patients with painful muscle spasm caused by five common musculoskeletal diseases were included in a double-blind controlled trial of chlormezanone, orphenadrine, orphenadrine/paracetomol and placebo. Patients were treated for one week and then asked fo …
Four hundred patients with painful muscle spasm caused by five common musculoskeletal diseases were included in a double-blind controlled tr …
Controlled clinical trial of oral and parenteral nefopam hydrochloride. A novel and potent analgesic drug.
Gassel MM, Diamantopoulos E, Petropoulos V, Hughes AC, Ballesteros ML, Ré ON. Gassel MM, et al. J Clin Pharmacol. 1976 Jan;16(1):34-41. doi: 10.1002/j.1552-4604.1976.tb01489.x. J Clin Pharmacol. 1976. PMID: 1107359 Clinical Trial.
The results of a controlled, double-blind clinical trial are reported demonstrating the potency of analgesia produced by orally and parenterally administered nefopam HCl in hospitalized patients with pain principally of skeletal and neuromuscular origin. The drug is an analogue o …
The results of a controlled, double-blind clinical trial are reported demonstrating the potency of analgesia produced by orally and parenter …
A comparative trial of orphenadrine and tofenacin in the control of depression and extrapyramidal side-effects associated with fluphenazine decanoate therapy.
Capstick N, Pudney H. Capstick N, et al. J Int Med Res. 1976;4(6):435-40. doi: 10.1177/030006057600400610. J Int Med Res. 1976. PMID: 800383 Clinical Trial.
A trial involving patients receiving fluphenazine decanoate was designed to compare the effects of orphenadrine hydrochloride (Disipal) and its major metabolite, tofenacin hydrochloride (Elamol) on the Parkinsonian side-effects and depression occurring during fluphenazine …
A trial involving patients receiving fluphenazine decanoate was designed to compare the effects of orphenadrine hydrochloride (Disipa …
Intravenous diclofenac and orphenadrine for the treatment of postoperative pain after remifentanil-based anesthesia : A double-blinded, randomized, placebo-controlled study.
Zeiner S, Haider T, Zotti O, Thüringer K, Höbart P, Kimberger O, Knolle E. Zeiner S, et al. Wien Klin Wochenschr. 2023 Feb;135(3-4):67-74. doi: 10.1007/s00508-022-02131-x. Epub 2022 Dec 28. Wien Klin Wochenschr. 2023. PMID: 36576555 Free PMC article. Clinical Trial.
The objective of this study was to compare the analgesic efficacy of diclofenac-orphenadrine, diclofenac alone and saline. METHODS: We performed a double-blind, randomized, placebo-controlled, parallel-group, single-center clinical study investigating the opioid-sparing ef …
The objective of this study was to compare the analgesic efficacy of diclofenac-orphenadrine, diclofenac alone and saline. METHODS: W …
Postoperative analgesia using papaveretum and orphenadrine. A preliminary trial.
Fry EN. Fry EN. Anaesthesia. 1979 Mar;34(3):281-3. doi: 10.1111/j.1365-2044.1979.tb06311.x. Anaesthesia. 1979. PMID: 378020 Free article. Clinical Trial.
The action of orphenadrine when given towards the end of a general anaesthetic is described. It is shown to delay the need for postoperative analgesia and extend the analgesic action of papaveretum....
The action of orphenadrine when given towards the end of a general anaesthetic is described. It is shown to delay the need for postop …
[Analgesic and opioid-sparing effects of a fixed combination of diclofenac and orphenadrine in the early postoperative period in cardiac surgery patients].
Eremenko AA, Sorokina LS, Ryabova DV, Urbanov AV. Eremenko AA, et al. Zh Nevrol Psikhiatr Im S S Korsakova. 2022;122(10):109-115. doi: 10.17116/jnevro2022122101109. Zh Nevrol Psikhiatr Im S S Korsakova. 2022. PMID: 36279236 Clinical Trial. Russian.
In 20 patients (group 1), "Neodolpasse" (a fixed combination of 30 mg Orphenadrine and 75 mg Diclofenac) was administered immediately after trachea extubation. ...The analgesic effect of the combination of orphenadrine and diclofenac had a positive effect on the fun …
In 20 patients (group 1), "Neodolpasse" (a fixed combination of 30 mg Orphenadrine and 75 mg Diclofenac) was administered immediately …
Orphenadrine in treatment of muscle cramps in cirrhotic patients: a randomized study.
Abd-Elsalam S, Ebrahim S, Soliman S, Alkhalawany W, Elfert A, Hawash N, Elkadeem M, Badawi R. Abd-Elsalam S, et al. Eur J Gastroenterol Hepatol. 2020 Aug;32(8):1042-1045. doi: 10.1097/MEG.0000000000001622. Eur J Gastroenterol Hepatol. 2020. PMID: 31834056 Clinical Trial.
They were divided into two arms: 62 patients administrated orphenadrine and 62 administrated placebo. They were followed up till 2 weeks after the end of therapy. Muscle cramps were evaluated using questionnaire as regards severity, duration, and frequency. Also, side effe …
They were divided into two arms: 62 patients administrated orphenadrine and 62 administrated placebo. They were followed up till 2 we …
Efficacy and safety of combined piroxicam, dexamethasone, orphenadrine, and cyanocobalamin treatment in mandibular molar surgery.
Barroso AB, Lima V, Guzzo GC, Moraes RA, Vasconcellos MC, Bezerra MM, Viana FA, Bezerra RC, Santana GS, Frota-Bezerra FA, Moraes MO, Moraes ME. Barroso AB, et al. Braz J Med Biol Res. 2006 Sep;39(9):1241-7. doi: 10.1590/s0100-879x2006000900012. Braz J Med Biol Res. 2006. PMID: 16981050 Free article. Clinical Trial.
The aim of the present study was to determine the efficacy and safety of the therapeutic combination of 10 mg piroxicam, 1 mg dexamethasone, 35 mg orphenadrine citrate, and 2.5 mg cyanocobalamin (Rheumazin) when compared with 20 mg piroxicam alone (Feldene) in mandibular t …
The aim of the present study was to determine the efficacy and safety of the therapeutic combination of 10 mg piroxicam, 1 mg dexamethasone, …
[Pain relief after abdominal oncologic surgery. Evaluation of the effectiveness and safety of a fixed combination of diclofenac and orphenadrine].
Semenkov AV, Skugarev AL, Tulskih DA, Khitrov NV, Yavorovskaya DA, Sergeev OS. Semenkov AV, et al. Khirurgiia (Mosk). 2024;(9):38-50. doi: 10.17116/hirurgia202409138. Khirurgiia (Mosk). 2024. PMID: 39268735 Clinical Trial. Russian.
OBJECTIVE: Evaluation of the analgesic, opioid-sparing, anti-inflammatory and adverse effects of the diclofenac and orphenadrine (Neodolpasse) fixed combination for analgesia in the postoperative period of surgical cancer patients. ...In the first group N (n=20), "Neodolpa …
OBJECTIVE: Evaluation of the analgesic, opioid-sparing, anti-inflammatory and adverse effects of the diclofenac and orphenadrine (Neo …
76 results