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Year Number of Results
1967 1
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1980 1
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1986 2
1988 1
1989 5
1990 5
1991 2
1994 3
1995 6
1996 7
1997 6
1998 12
1999 9
2000 13
2001 13
2002 9
2003 12
2004 15
2005 16
2006 17
2007 21
2008 17
2009 9
2010 11
2011 14
2012 12
2013 12
2014 12
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2016 6
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2024 5
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2026 0

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316 results

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Page 1
The Combination of Atomoxetine and Oxybutynin Greatly Reduces Obstructive Sleep Apnea Severity. A Randomized, Placebo-controlled, Double-Blind Crossover Trial.
Taranto-Montemurro L, Messineo L, Sands SA, Azarbarzin A, Marques M, Edwards BA, Eckert DJ, White DP, Wellman A. Taranto-Montemurro L, et al. Am J Respir Crit Care Med. 2019 May 15;199(10):1267-1276. doi: 10.1164/rccm.201808-1493OC. Am J Respir Crit Care Med. 2019. PMID: 30395486 Free PMC article. Clinical Trial.
Objectives: We aimed to determine the effects of the combination of a norepinephrine reuptake inhibitor (atomoxetine) and an antimuscarinic (oxybutynin) on OSA severity (apnea-hypopnea index [AHI]; primary outcome) and genioglossus responsiveness (secondary outcome) in peo …
Objectives: We aimed to determine the effects of the combination of a norepinephrine reuptake inhibitor (atomoxetine) and an antimuscarinic …
A muscarinic receptor antagonist reverses multiple indices of diabetic peripheral neuropathy: preclinical and clinical studies using oxybutynin.
Casselini CM, Parson HK, Frizzi KE, Marquez A, Smith DR, Guernsey L, Nemmani R, Tayarani A, Jolivalt CG, Weaver J, Fernyhough P, Vinik AI, Calcutt NA. Casselini CM, et al. Acta Neuropathol. 2024 Mar 25;147(1):60. doi: 10.1007/s00401-024-02710-4. Acta Neuropathol. 2024. PMID: 38526612 Free article. Clinical Trial.
Subjects received daily topical treatment with 3% oxybutynin gel or placebo for 6 months. The a priori designated primary endpoint, significant change in intra-epidermal nerve fibre density (IENFD) in skin biopsies taken before and after 20 weeks of treatments, was met by …
Subjects received daily topical treatment with 3% oxybutynin gel or placebo for 6 months. The a priori designated primary endpoint, s …
Effect of oxybutynin and reboxetine on obstructive sleep apnea: a randomized, placebo-controlled, double-blind, crossover trial.
Berger M, Solelhac G, Marchi NA, Dussez R, Bradley B, Lecciso G, Heiniger G, Bayon V, Van Den Broecke S, Haba-Rubio J, Siclari F, Heinzer R. Berger M, et al. Sleep. 2023 Jul 11;46(7):zsad051. doi: 10.1093/sleep/zsad051. Sleep. 2023. PMID: 36861433 Clinical Trial.
The present study aimed to evaluate the effect of 1 week of 5 mg oxybutynin and 6 mg reboxetine (oxy-reb) on OSA versus placebo. METHODS: We performed a randomized, placebo-controlled, double-blind, crossover trial comparing the effect of 1 week of oxy-reb versus 1 week of …
The present study aimed to evaluate the effect of 1 week of 5 mg oxybutynin and 6 mg reboxetine (oxy-reb) on OSA versus placebo. METH …
Combination of atomoxetine with the novel antimuscarinic aroxybutynin improves mild to moderate OSA.
Rosenberg R, Abaluck B, Thein S. Rosenberg R, et al. J Clin Sleep Med. 2022 Dec 1;18(12):2837-2844. doi: 10.5664/jcsm.10250. J Clin Sleep Med. 2022. PMID: 35975547 Free PMC article. Clinical Trial.
Previous pharmacological studies addressing sleep-related upper airway muscle hypotonia suggested that the combination of atomoxetine and oxybutynin is effective in treating obstructive sleep apnea. The current study is with aroxybutynin (AD109), a new enantiomerically pur …
Previous pharmacological studies addressing sleep-related upper airway muscle hypotonia suggested that the combination of atomoxetine and …
The combination of atomoxetine and oxybutynin for the treatment of obstructive sleep apnea in children with Down syndrome.
Combs D, Edgin J, Hsu CH, Bottrill K, Van Vorce H, Gerken B, Matloff D, La Rue S, Parthasarathy S. Combs D, et al. J Clin Sleep Med. 2023 Dec 1;19(12):2065-2073. doi: 10.5664/jcsm.10764. J Clin Sleep Med. 2023. PMID: 37555595 Free PMC article. Clinical Trial.
Participants received low-dose ato-oxy (0.5 mg/kg atomoxetine and 5 mg oxybutynin) and high-dose ato-oxy (1.2 mg/kg atomoxetine and 5 mg oxybutynin) for 1 month in random order. ...CITATION: Combs D, Edgin J, Hsu C-H, et al. The combination of atomoxetine and oxy …
Participants received low-dose ato-oxy (0.5 mg/kg atomoxetine and 5 mg oxybutynin) and high-dose ato-oxy (1.2 mg/kg atomoxetine and 5 …
Oxybutynin, desmopressin and enuresis.
Nevéus T. Nevéus T. J Urol. 2001 Dec;166(6):2459-62. doi: 10.1016/s0022-5347(05)65616-9. J Urol. 2001. PMID: 11696812 Clinical Trial.
PURPOSE: A review of the scarce literature concerning oxybutynin treatment for nocturnal enuresis reveals that its success is greatest when enuresis is combined with daytime incontinence. The renal and bladder related characteristics of children with monosymptomatic enures …
PURPOSE: A review of the scarce literature concerning oxybutynin treatment for nocturnal enuresis reveals that its success is greates …
Once-daily oxybutynin patch improves nocturia and sleep quality in Japanese patients with overactive bladder: Post-hoc analysis of a phase III randomized clinical trial.
Yokoyama O, Yamaguchi A, Yoshida M, Yamanishi T, Ishizuka O, Seki N, Takahashi S, Yamaguchi O, Higo N, Minami H, Masegi Y. Yokoyama O, et al. Int J Urol. 2015 Jul;22(7):684-8. doi: 10.1111/iju.12755. Epub 2015 Mar 17. Int J Urol. 2015. PMID: 25782032 Clinical Trial.
OBJECTIVES: To investigate the efficacy of a once-daily oxybutynin patch for nocturia, and its influence on sleep quality in patients with overactive bladder. ...The number of nocturia episodes decreased by 0.66 in the oxybutynin patch group versus 0.51 in the place …
OBJECTIVES: To investigate the efficacy of a once-daily oxybutynin patch for nocturia, and its influence on sleep quality in patients …
One Month Dosing of Atomoxetine plus Oxybutynin in Obstructive Sleep Apnea: A Randomized, Placebo-controlled Trial.
Aishah A, Loffler KA, Toson B, Mukherjee S, Adams RJ, Altree TJ, Ainge-Allen HW, Yee BJ, Grunstein RR, Carberry JC, Eckert DJ. Aishah A, et al. Ann Am Thorac Soc. 2023 Apr;20(4):584-595. doi: 10.1513/AnnalsATS.202206-492OC. Ann Am Thorac Soc. 2023. PMID: 36538809 Clinical Trial.
Objectives: To determine the safety, tolerability, and potential efficacy of longer term use of different doses of the noradrenergic agent atomoxetine combined with the antimuscarinic oxybutynin (ato-oxy). Methods: Thirty-nine people with predominantly severe OSA received …
Objectives: To determine the safety, tolerability, and potential efficacy of longer term use of different doses of the noradrenergic agent a …
A randomized controlled trial of tolterodine and oxybutynin on tolerability and clinical efficacy for treating Chinese women with an overactive bladder.
Leung HY, Yip SK, Cheon C, Liu YS, Lau J, Wong HK, Chung KH. Leung HY, et al. BJU Int. 2002 Sep;90(4):375-80. doi: 10.1046/j.1464-410x.2002.02905.x. BJU Int. 2002. PMID: 12175392 Clinical Trial.
The women were randomized to receive either oral tolterodine 2 mg or oxybutynin 5 mg twice daily for 10 weeks. Treatment responses were assessed at 4 and 10 weeks using the VAS and urinary diary. ...Tolterodine was significantly better than oxybutynin in reducing ur …
The women were randomized to receive either oral tolterodine 2 mg or oxybutynin 5 mg twice daily for 10 weeks. Treatment responses we …
Extended-release oxybutynin therapy for vasomotor symptoms in women: a randomized clinical trial.
Simon JA, Gaines T, LaGuardia KD; Extended-Release Oxybutynin Therapy for VMS Study Group. Simon JA, et al. Menopause. 2016 Nov;23(11):1214-1221. doi: 10.1097/GME.0000000000000773. Menopause. 2016. PMID: 27760081 Clinical Trial.
Mean changes in severity (scale 0-3) in the oxybutynin and placebo groups were -1.27 and -0.30, respectively, at week 12. At the end of treatment, 73% of women in the oxybutynin group and 26.1% in the placebo group rated symptom improvement "much better" (P 0.001). …
Mean changes in severity (scale 0-3) in the oxybutynin and placebo groups were -1.27 and -0.30, respectively, at week 12. At the end …
316 results