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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1971 1
1973 1
1978 2
1979 2
1980 4
1981 6
1983 2
1984 1
1985 3
1986 4
1987 6
1988 4
1989 3
1990 3
1991 5
1992 8
1993 8
1994 7
1995 5
1996 11
1997 10
1998 15
1999 11
2000 12
2001 10
2002 17
2003 13
2004 28
2005 24
2006 27
2007 26
2008 41
2009 46
2010 50
2011 56
2012 52
2013 49
2014 47
2015 55
2016 55
2017 59
2018 55
2019 46
2020 54
2021 35
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885 results
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A comparison of oral controlled-release morphine and oxycodone with transdermal formulations of buprenorphine and fentanyl in the treatment of severe pain in cancer patients.
Nosek K, Leppert W, Nosek H, Wordliczek J, Onichimowski D. Nosek K, et al. Drug Des Devel Ther. 2017 Aug 22;11:2409-2419. doi: 10.2147/DDDT.S141007. eCollection 2017. Drug Des Devel Ther. 2017. PMID: 28860712 Free PMC article. Clinical Trial.
AIM OF THE STUDY: To compare analgesia and adverse effects during oral morphine and oxycodone and transdermal fentanyl and buprenorphine administration in cancer patients with pain. PATIENTS AND METHODS: Cancer patients treated at home and in outpatient clinics with severe …
AIM OF THE STUDY: To compare analgesia and adverse effects during oral morphine and oxycodone and transdermal fentanyl and buprenorph …
Impact of co-administration of oxycodone and smoked cannabis on analgesia and abuse liability.
Cooper ZD, Bedi G, Ramesh D, Balter R, Comer SD, Haney M. Cooper ZD, et al. Neuropsychopharmacology. 2018 Sep;43(10):2046-2055. doi: 10.1038/s41386-018-0011-2. Epub 2018 Feb 5. Neuropsychopharmacology. 2018. PMID: 29463913 Free PMC article. Clinical Trial.
However, the combination of 2.5 mg oxycodone and active cannabis produced small, yet significant, increases in oxycodone abuse liability (p 0.05). Cannabis enhances the analgesic effects of sub-threshold oxycodone, suggesting synergy, without increases in can …
However, the combination of 2.5 mg oxycodone and active cannabis produced small, yet significant, increases in oxycodone abuse …
Cannabinoid-opioid interaction in chronic pain.
Abrams DI, Couey P, Shade SB, Kelly ME, Benowitz NL. Abrams DI, et al. Clin Pharmacol Ther. 2011 Dec;90(6):844-51. doi: 10.1038/clpt.2011.188. Epub 2011 Nov 2. Clin Pharmacol Ther. 2011. PMID: 22048225 Clinical Trial.
Twenty-one individuals with chronic pain, on a regimen of twice-daily doses of sustained-release morphine or oxycodone were enrolled in the study and admitted for a 5-day inpatient stay. ...Pharmacokinetic investigations revealed no significant change in the area under the …
Twenty-one individuals with chronic pain, on a regimen of twice-daily doses of sustained-release morphine or oxycodone were enrolled …
Oxycodone versus sufentanil in adult patient-controlled intravenous analgesia after abdominal surgery: A prospective, randomized, double-blinded, multiple-center clinical trial.
Han L, Su Y, Xiong H, Niu X, Dang S, Du K, Li Q, Liu J, Zhang P, Li S. Han L, et al. Medicine (Baltimore). 2018 Aug;97(31):e11552. doi: 10.1097/MD.0000000000011552. Medicine (Baltimore). 2018. PMID: 30075523 Free PMC article. Clinical Trial.
RESULTS: A total of 200 patients were screened, and 175 patients were enrolled. Patients were randomly assigned to oxycodone (n = 87) and sufentanil (n = 88) groups. Both oxycodone and sufentanil PCIA provided adequate postoperative pain relief. Patients in oxyco
RESULTS: A total of 200 patients were screened, and 175 patients were enrolled. Patients were randomly assigned to oxycodone (n = 87) …
Efficacy and safety of sustained-release oxycodone compared with immediate-release morphine for pain titration in cancer patients: A multicenter, open-label, randomized controlled trial (SOCIAL).
Pan H, Shen P, Shu Q, Lu L, Qian S, Zhou Y, Han F, Guo Q, Yang Z, Pan J, Xu Q, Zhang P, Wang K. Pan H, et al. Medicine (Baltimore). 2019 Jun;98(24):e15505. doi: 10.1097/MD.0000000000015505. Medicine (Baltimore). 2019. PMID: 31192908 Free PMC article. Clinical Trial.
Oxycodone prescription significantly increased the response rate of patients to morphine titration during the first cycle of titration (P = .010). The initial NRS score and oxycodone administration were significantly associated with titration performance. ...
Oxycodone prescription significantly increased the response rate of patients to morphine titration during the first cycle of titratio
Are strong opioids equally effective and safe in the treatment of chronic cancer pain? A multicenter randomized phase IV 'real life' trial on the variability of response to opioids.
Corli O, Floriani I, Roberto A, Montanari M, Galli F, Greco MT, Caraceni A, Kaasa S, Dragani TA, Azzarello G, Luzzani M, Cavanna L, Bandieri E, Gamucci T, Lipari G, Di Gregorio R, Valenti D, Reale C, Pavesi L, Iorno V, Crispino C, Pacchioni M, Apolone G; CERP STUDY OF PAIN GROUP (List of collaborators). Corli O, et al. Ann Oncol. 2016 Jun;27(6):1107-1115. doi: 10.1093/annonc/mdw097. Epub 2016 Mar 2. Ann Oncol. 2016. PMID: 26940689 Free article. Clinical Trial.
PATIENT AND METHODS: In this four-arm multicenter, randomized, comparative, of superiority, phase IV trial, oncological patients with moderate to severe pain requiring WHO step III opioids were randomly assigned to receive oral morphine or oxycodone or transdermal fentanyl …
PATIENT AND METHODS: In this four-arm multicenter, randomized, comparative, of superiority, phase IV trial, oncological patients with modera …
Oxycodone and dexamethasone for pain management after tonsillectomy: a placebo-controlled EMG assessed clinical trial.
Vaiman M, Krakovski D, Haitov Z. Vaiman M, et al. Med Sci Monit. 2011 Oct;17(10):PI25-31. doi: 10.12659/msm.881964. Med Sci Monit. 2011. PMID: 21959624 Free PMC article. Clinical Trial.
BACKGROUND: Surface electromyographic (sEMG) study of post-tonsillectomy swallow-evoked muscular reactions was performed in order to evaluate the efficacy and safety of oxycodone and dexamethasone in pain management after tonsillectomy. ...The sEMG data were compared with …
BACKGROUND: Surface electromyographic (sEMG) study of post-tonsillectomy swallow-evoked muscular reactions was performed in order to evaluat …
Effects of anaesthesia method and tourniquet use on recovery following total knee arthroplasty: a randomised controlled study.
Palanne R, Rantasalo M, Vakkuri A, Madanat R, Olkkola KT, Lahtinen K, Reponen E, Linko R, Vahlberg T, Skants N. Palanne R, et al. Br J Anaesth. 2020 Nov;125(5):762-772. doi: 10.1016/j.bja.2020.03.036. Epub 2020 Jun 30. Br J Anaesth. 2020. PMID: 32620260 Clinical Trial.
METHODS: Patients (n=413) were randomised to four parallel groups: spinal anaesthesia with or without tourniquet, and general anaesthesia with or without tourniquet. The primary outcome was patient-controlled i.v. oxycodone consumption over 24 postoperative hours. RESULTS: …
METHODS: Patients (n=413) were randomised to four parallel groups: spinal anaesthesia with or without tourniquet, and general anaesthesia wi …
Comparison of oral oxycodone and naproxen in soft tissue injury pain control: a double-blind randomized clinical trial.
Fathi M, Zare MA, Bahmani HR, Zehtabchi S. Fathi M, et al. Am J Emerg Med. 2015 Sep;33(9):1205-8. doi: 10.1016/j.ajem.2015.05.021. Epub 2015 May 29. Am J Emerg Med. 2015. PMID: 26166378 Clinical Trial.
Adverse effects were more common in oxycodone group (statistically significant difference). The most common adverse effects in oxycodone group were nausea, (13.3%); vomiting, (8.0%); dizziness, (5.3%); drowsiness, 3 (4.0%); and pruritis, (2.7%). CONCLUSION: Oral …
Adverse effects were more common in oxycodone group (statistically significant difference). The most common adverse effects in oxy
Post hoc analyses of data from a 90-day clinical trial evaluating the tolerability and efficacy of tapentadol immediate release and oxycodone immediate release for the relief of moderate to severe pain in elderly and nonelderly patients.
Vorsanger G, Xiang J, Biondi D, Upmalis D, Delfgaauw J, Allard R, Moskovitz B. Vorsanger G, et al. Pain Res Manag. 2011 Jul-Aug;16(4):245-51. doi: 10.1155/2011/323985. Pain Res Manag. 2011. PMID: 22059194 Free PMC article. Clinical Trial.
Among elderly patients, incidences of constipation (19.0% versus 35.6%) and nausea or vomiting (30.4% versus 51.1%) were significantly lower with tapentadol IR versus oxycodone IR (all P<0.05). Initial onsets of nausea and constipation occurred significantly later with …
Among elderly patients, incidences of constipation (19.0% versus 35.6%) and nausea or vomiting (30.4% versus 51.1%) were significantly lower …
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