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1973 6
1974 18
1975 11
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1977 9
1978 15
1979 13
1980 7
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1982 8
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1987 30
1988 21
1989 29
1990 28
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1998 52
1999 45
2000 39
2001 55
2002 39
2003 44
2004 56
2005 54
2006 46
2007 52
2008 57
2009 62
2010 74
2011 83
2012 115
2013 115
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2,470 results

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Page 1
Intranasal Oxytocin in Children and Adolescents with Autism Spectrum Disorder.
Sikich L, Kolevzon A, King BH, McDougle CJ, Sanders KB, Kim SJ, Spanos M, Chandrasekhar T, Trelles MDP, Rockhill CM, Palumbo ML, Witters Cundiff A, Montgomery A, Siper P, Minjarez M, Nowinski LA, Marler S, Shuffrey LC, Alderman C, Weissman J, Zappone B, Mullett JE, Crosson H, Hong N, Siecinski SK, Giamberardino SN, Luo S, She L, Bhapkar M, Dean R, Scheer A, Johnson JL, Gregory SG, Veenstra-VanderWeele J. Sikich L, et al. N Engl J Med. 2021 Oct 14;385(16):1462-1473. doi: 10.1056/NEJMoa2103583. N Engl J Med. 2021. PMID: 34644471 Free PMC article. Clinical Trial.
BACKGROUND: Experimental studies and small clinical trials have suggested that treatment with intranasal oxytocin may reduce social impairment in persons with autism spectrum disorder. Oxytocin has been administered in clinical practice to many children with autism …
BACKGROUND: Experimental studies and small clinical trials have suggested that treatment with intranasal oxytocin may reduce social i …
Carbetocin vs. oxytocin at elective caesarean delivery: a double-blind, randomised, controlled, non-inferiority trial of low- and high-dose regimens.
McDonagh F, Carvalho JCA, Abdulla S, Cordovani D, Downey K, Ye XY, Farine D, Morais M, Balki M. McDonagh F, et al. Anaesthesia. 2022 Aug;77(8):892-900. doi: 10.1111/anae.15714. Epub 2022 Mar 28. Anaesthesia. 2022. PMID: 35343585 Free article. Clinical Trial.
Carbetocin or oxytocin are given routinely as first-line uterotonic drugs following delivery of the neonate during caesarean delivery to prevent postpartum haemorrhage. ...Carbetocin 20 mug was also non-inferior to oxytocin 5 IU, and oxytocin 0.5 IU was non-i …
Carbetocin or oxytocin are given routinely as first-line uterotonic drugs following delivery of the neonate during caesarean delivery …
The effect of oxytocin nasal spray on social interaction in young children with autism: a randomized clinical trial.
Guastella AJ, Boulton KA, Whitehouse AJO, Song YJ, Thapa R, Gregory SG, Pokorski I, Granich J, DeMayo MM, Ambarchi Z, Wray J, Thomas EE, Hickie IB. Guastella AJ, et al. Mol Psychiatry. 2023 Feb;28(2):834-842. doi: 10.1038/s41380-022-01845-8. Epub 2022 Oct 27. Mol Psychiatry. 2023. PMID: 36302965 Free PMC article. Clinical Trial.
Overall, there was no effect of oxytocin treatment over time on the caregiver-rated Social Responsiveness Scale (SRS-2) (p = 0.686). ...This study suggests the need for further clinical trials to test the benefits of oxytocin treatment in younger populations with au …
Overall, there was no effect of oxytocin treatment over time on the caregiver-rated Social Responsiveness Scale (SRS-2) (p = 0.686). …
Intranasal Oxytocin for Obesity.
Plessow F, Kerem L, Wronski ML, Asanza E, O'Donoghue ML, Stanford FC, Eddy KT, Holmes TM, Misra M, Thomas JJ, Galbiati F, Muhammed M, Sella AC, Hauser K, Smith SE, Holman K, Gydus J, Aulinas A, Vangel M, Healy B, Kheterpal A, Torriani M, Holsen LM, Bredella MA, Lawson EA. Plessow F, et al. NEJM Evid. 2024 May;3(5):EVIDoa2300349. doi: 10.1056/EVIDoa2300349. Epub 2024 Apr 23. NEJM Evid. 2024. PMID: 38815173 Clinical Trial.
BACKGROUND: Accumulating preclinical and preliminary translational evidence shows that the hypothalamic peptide oxytocin reduces food intake, increases energy expenditure, and promotes weight loss. It is currently unknown whether oxytocin administration is effective …
BACKGROUND: Accumulating preclinical and preliminary translational evidence shows that the hypothalamic peptide oxytocin reduces food …
A randomized, double-blind, placebo-controlled clinical trial of 8-week intranasal oxytocin administration in adults with obesity: Rationale, study design, and methods.
Wronski ML, Plessow F, Kerem L, Asanza E, O'Donoghue ML, Stanford FC, Bredella MA, Torriani M, Soukas AA, Kheterpal A, Eddy KT, Holmes TM, Deckersbach T, Vangel M, Holsen LM, Lawson EA. Wronski ML, et al. Contemp Clin Trials. 2022 Nov;122:106909. doi: 10.1016/j.cct.2022.106909. Epub 2022 Sep 7. Contemp Clin Trials. 2022. PMID: 36087842 Free PMC article. Clinical Trial.
We study intranasal oxytocin, an investigational drug shown to reduce caloric intake in humans, as a potential novel treatment for obesity. ...The study sample is diverse with 38% identifying as non-White and 20% Hispanic. CONCLUSION: Investigating intranasal oxytocin …
We study intranasal oxytocin, an investigational drug shown to reduce caloric intake in humans, as a potential novel treatment for ob …
Oxytocin and social learning in socially anxious men and women.
Flechsenhar A, Levine SM, Müller LE, Herpertz SC, Bertsch K. Flechsenhar A, et al. Neuropharmacology. 2024 Jun 15;251:109930. doi: 10.1016/j.neuropharm.2024.109930. Epub 2024 Mar 25. Neuropharmacology. 2024. PMID: 38537867 Free article. Clinical Trial.
As an objective physiological measure of arousal, pupil dilation mirrored the behavioral results. Oxytocin effects on neural activation in the insula interacted with anxiety levels and sex: low socially anxious individuals yielded lower activation under oxytocin tha …
As an objective physiological measure of arousal, pupil dilation mirrored the behavioral results. Oxytocin effects on neural activati …
Neural Responses to Intranasal Oxytocin in Youths With Severe Irritability.
Hwang S, Suk JW, Meffert H, Lerdahl A, Garvey WF, Edwards R, Delizza A, Soltis-Vaughan B, Cordts K, Leibenluft E, Blair RJR. Hwang S, et al. Am J Psychiatry. 2024 Apr 1;181(4):291-298. doi: 10.1176/appi.ajp.20230174. Epub 2024 Feb 29. Am J Psychiatry. 2024. PMID: 38419495 Free PMC article. Clinical Trial.
Forty-three participants (22 in the oxytocin group and 21 in the placebo group) completed pre- and posttreatment functional MRI (fMRI) scans with the affective Stroop task. RESULTS: Youths who received oxytocin showed significant improvement in CGI-S and CGI-I ratin …
Forty-three participants (22 in the oxytocin group and 21 in the placebo group) completed pre- and posttreatment functional MRI (fMRI …
Design of a randomized clinical trial of brief couple therapy for PTSD augmented with intranasal oxytocin.
Sippel LM, Wachsman TR, Kelley ME, Knopp KC, Khalifian CE, Maglione JE, Glynn SM, Macdonald A, Monson CM, Flanagan JC, Holtzheimer PE, Morland LA. Sippel LM, et al. Contemp Clin Trials. 2024 Jun;141:107534. doi: 10.1016/j.cct.2024.107534. Epub 2024 Apr 12. Contemp Clin Trials. 2024. PMID: 38614447 Clinical Trial.
Although efficacious in improving PTSD, the effects of CBCT on relationship satisfaction are small, especially among veterans. Intranasal oxytocin, which targets mechanisms of PTSD and relationship quality, may enhance the efficacy of bCBCT. ...Veterans will be administere …
Although efficacious in improving PTSD, the effects of CBCT on relationship satisfaction are small, especially among veterans. Intranasal …
The Effects of Oxytocin on Craving, Mental Health Parameters, and Stress Hormones in Methamphetamine-Dependent Patients Undergoing Matrix Treatment Model: A Randomized, Double-Blind Clinical Trial.
Azadbakht A, Salehi M, Maracy MR, Banafshe HR. Azadbakht A, et al. Eur Addict Res. 2022;28(5):340-349. doi: 10.1159/000525443. Epub 2022 Aug 2. Eur Addict Res. 2022. PMID: 35917806 Clinical Trial.
BACKGROUND: Methamphetamine (METH) dependence is an increasing public health problem with a wide range of mental and physical adverse effects. Recent studies report that oxytocin (OXT) has potential therapeutic properties in drug dependence. Hence, the present study was de …
BACKGROUND: Methamphetamine (METH) dependence is an increasing public health problem with a wide range of mental and physical adverse effect …
Effects of oxytocin administration on fear-potentiated acoustic startle in co-occurring PTSD and alcohol use disorder: A randomized clinical trial.
Stauffer CS, Morrison TE, Meinzer NK, Leung D, Buffington J, Sheh EG, Neylan TC, O'Donovan A, Woolley JD. Stauffer CS, et al. Psychiatry Res. 2022 Feb;308:114340. doi: 10.1016/j.psychres.2021.114340. Epub 2021 Dec 12. Psychiatry Res. 2022. PMID: 34983010 Free PMC article. Clinical Trial.
Co-occurring posttraumatic stress disorder (PTSD) and alcohol use disorder (AUD) is common and particularly associated with elevation of hyperarousal compared to PTSD alone. Treatment options are limited. Oxytocin regulates physiological stress response. Intranasal oxyt …
Co-occurring posttraumatic stress disorder (PTSD) and alcohol use disorder (AUD) is common and particularly associated with elevation of hyp …
2,470 results