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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1963 1
1965 11
1966 16
1967 20
1968 37
1969 33
1970 52
1971 47
1972 50
1973 55
1974 81
1975 78
1976 75
1977 52
1978 108
1979 95
1980 93
1981 116
1982 101
1983 121
1984 157
1985 206
1986 218
1987 240
1988 253
1989 324
1990 372
1991 447
1992 458
1993 545
1994 803
1995 896
1996 880
1997 934
1998 929
1999 972
2000 896
2001 831
2002 975
2003 1080
2004 1111
2005 1284
2006 1150
2007 1095
2008 1044
2009 1022
2010 1156
2011 1253
2012 1315
2013 1396
2014 1374
2015 1281
2016 1225
2017 1269
2018 1140
2019 1103
2020 1169
2021 1242
2022 1050
2023 936
2024 686

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34,294 results

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Page 1
Conservative versus liberal oxygenation targets in critically ill children (Oxy-PICU): a UK multicentre, open, parallel-group, randomised clinical trial.
Peters MJ, Gould DW, Ray S, Thomas K, Chang I, Orzol M, O'Neill L, Agbeko R, Au C, Draper E, Elliot-Major L, Giallongo E, Jones GAL, Lampro L, Lillie J, Pappachan J, Peters S, Ramnarayan P, Sadique Z, Rowan KM, Harrison DA, Mouncey PR; Oxy-PICU Investigators of the Paediatric Critical Care Society Study Group (PCCS-SG). Peters MJ, et al. Lancet. 2024 Jan 27;403(10424):355-364. doi: 10.1016/S0140-6736(23)01968-2. Epub 2023 Dec 1. Lancet. 2024. PMID: 38048787 Free article. Clinical Trial.
BACKGROUND: The optimal target for systemic oxygenation in critically ill children is unknown. Liberal oxygenation is widely practiced, but has been associated with harm in paediatric patients. ...Prespecified adverse events were reported in 24 (3%) of 939 patients …
BACKGROUND: The optimal target for systemic oxygenation in critically ill children is unknown. Liberal oxygenation is widely p …
Metformin inhibits mitochondrial adaptations to aerobic exercise training in older adults.
Konopka AR, Laurin JL, Schoenberg HM, Reid JJ, Castor WM, Wolff CA, Musci RV, Safairad OD, Linden MA, Biela LM, Bailey SM, Hamilton KL, Miller BF. Konopka AR, et al. Aging Cell. 2019 Feb;18(1):e12880. doi: 10.1111/acel.12880. Epub 2018 Dec 11. Aging Cell. 2019. PMID: 30548390 Free PMC article. Clinical Trial.
The purpose of this study was to test the hypothesis that metformin diminishes the improvement in insulin sensitivity and cardiorespiratory fitness after aerobic exercise training (AET) by inhibiting skeletal muscle mitochondrial respiration and protein synthesis in older …
The purpose of this study was to test the hypothesis that metformin diminishes the improvement in insulin sensitivity and cardiorespiratory …
Uremia and Inadequate Oxygen Supply Induce Eryptosis and Intracellular Hypoxia in Red Blood Cells.
Dias GF, Tozoni SS, Bohnen G, Grobe N, Rodrigues SD, Meireles T, Nakao LS, Pecoits-Filho R, Kotanko P, Moreno-Amaral AN. Dias GF, et al. Cell Physiol Biochem. 2021 Jul 14;55(4):449-459. doi: 10.33594/000000396. Cell Physiol Biochem. 2021. PMID: 34259420 Free article. Clinical Trial.
We aimed to assess eryptosis and intracellular oxygen levels of RBC from hemodialysis patients (HD-RBC) and their response to hypoxia, uremia, and uremic toxins uptake inhibition. ...CONCLUSION: These findings suggest the participation of uremic toxins and hypoxia in the p …
We aimed to assess eryptosis and intracellular oxygen levels of RBC from hemodialysis patients (HD-RBC) and their response to hypoxia …
Pre-oxygenation--how long?
Berthoud M, Read DH, Norman J. Berthoud M, et al. Anaesthesia. 1983 Feb;38(2):96-102. doi: 10.1111/j.1365-2044.1983.tb13925.x. Anaesthesia. 1983. PMID: 6402951 Free article. Clinical Trial.
Pre-oxygenation was studied in 12 fit volunteers and 20 patients using an oxygen flow of 8 litres/minute delivered from a standard anaesthetic machine via a Magill or Bain breathing attachment. End-tidal nitrogen concentrations of 4% or less were achieved within 3 m …
Pre-oxygenation was studied in 12 fit volunteers and 20 patients using an oxygen flow of 8 litres/minute delivered from a stan …
A prospective, randomized Phase II clinical trial to evaluate the effect of combined hyperbaric and normobaric hyperoxia on cerebral metabolism, intracranial pressure, oxygen toxicity, and clinical outcome in severe traumatic brain injury.
Rockswold SB, Rockswold GL, Zaun DA, Liu J. Rockswold SB, et al. J Neurosurg. 2013 Jun;118(6):1317-28. doi: 10.3171/2013.2.JNS121468. Epub 2013 Mar 19. J Neurosurg. 2013. PMID: 23510092 Clinical Trial.
OBJECT: Preclinical and clinical investigations indicate that the positive effect of hyperbaric oxygen (HBO2) for severe traumatic brain injury (TBI) occurs after rather than during treatment. ...METHODS: Forty-two patients who sustained severe TBI (mean Glasgow Coma Scale …
OBJECT: Preclinical and clinical investigations indicate that the positive effect of hyperbaric oxygen (HBO2) for severe traumatic br …
Integrated Oxygenator FX05.
Horton SB, Donath S, Thuys CA, Bennett MJ, Augustin SL, Horton AM, Schultz BJ, Bottrell SJ, Konstantinov I, d'Udekem Y, Brizard C. Horton SB, et al. ASAIO J. 2011 Nov-Dec;57(6):522-6. doi: 10.1097/MAT.0b013e318232c1db. ASAIO J. 2011. PMID: 21970981 Clinical Trial.
In recent years, there has been a trend to incorporate arterial filters into cardiopulmonary bypass (CPB) oxygenators. The FX oxygenators are the first examples of integrating a filter around the fibers of the oxygenator. To assess the efficacy of the FX05 …
In recent years, there has been a trend to incorporate arterial filters into cardiopulmonary bypass (CPB) oxygenators. The FX oxyg …
Cardiorespiratory alterations in patients undergoing hyperbaric oxygen therapy.
Martinelli B, Noronha JM, Sette MFM, Santos IPD, Barrile SR, Simão JC. Martinelli B, et al. Rev Esc Enferm USP. 2019 Sep 5;53:e03469. doi: 10.1590/S1980-220X2017051503469. Rev Esc Enferm USP. 2019. PMID: 31508730 Free article. Clinical Trial. English, Portuguese.
OBJECTIVE: To evaluate cardiorespiratory alterations due to a single session of hyperbaric oxygen therapy. METHOD: Randomized study with patients: a control group and hyperbaric oxygen therapy. Evaluations occurred in the beginning, during, and after exposure to pur …
OBJECTIVE: To evaluate cardiorespiratory alterations due to a single session of hyperbaric oxygen therapy. METHOD: Randomized study w …
Ease and comfort of pre-oxygenation with high-flow nasal oxygen cannulae vs. facemask: a randomised controlled trial.
Merry AF, van Waart H, Allen SJ, Baker PA, Cumin D, Frampton CMA, Gargiulo DA, Hannam JA, Keogh GF, Moore MR, Payton M, Mitchell SJ. Merry AF, et al. Anaesthesia. 2022 Dec;77(12):1346-1355. doi: 10.1111/anae.15853. Epub 2022 Sep 15. Anaesthesia. 2022. PMID: 36110039 Free PMC article. Clinical Trial.
We tested the hypothesis that high-flow nasal oxygen cannulae would be easier and more comfortable than facemasks for pre-oxygenation. ...In conclusion, we found pre-oxygenation with high-flow nasal oxygen to be easier for anaesthetists and more comfor …
We tested the hypothesis that high-flow nasal oxygen cannulae would be easier and more comfortable than facemasks for pre-oxygenat …
Success and Time to Oxygen Delivery for Scalpel-Finger-Cannula and Scalpel-Finger-Bougie Front-of-Neck Access: A Randomized Crossover Study With a Simulated "Can't Intubate, Can't Oxygenate" Scenario in a Manikin Model With Impalpable Neck Anatomy.
Zhang J, Ong S, Toh H, Chew M, Ang H, Goh S. Zhang J, et al. Anesth Analg. 2022 Aug 1;135(2):376-384. doi: 10.1213/ANE.0000000000005969. Epub 2022 Mar 4. Anesth Analg. 2022. PMID: 35245225 Clinical Trial.

Participants also had higher odds at achieving first-attempt success with SFC than SFB (odds ratio [OR], 10.7; 95% CI, 3.3-35.0; P < .001). Successful delivery of oxygen after the "can't intubate, can't oxygenate" (CICO) declaration within 3 attempts and 180 seco

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Participants also had higher odds at achieving first-attempt success with SFC than SFB (odds ratio [OR], 10.7; 95% CI, 3.3-35.0; P < .001

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Hyperbaric oxygen therapy (HBOT) and peridontal health.
Ottria L, Tettamanti L, Gargari M, Valente G, Pacini V, Costanzo C. Ottria L, et al. J Biol Regul Homeost Agents. 2018 Jan-Feb;32(2 Suppl. 1):217-221. J Biol Regul Homeost Agents. 2018. PMID: 29460545 Clinical Trial.
This study has tested the effects of hyperbaric oxygen in periodontal structures in agreement with the theories supported by literature research. Eight patients, from 30 to 50 years-of-age, were tested with pure oxygen inhalation, at the 2.5 ATA absolute pressure. M …
This study has tested the effects of hyperbaric oxygen in periodontal structures in agreement with the theories supported by literatu …
34,294 results
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