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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1964 1
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1974 74
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1976 54
1977 71
1978 53
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1980 65
1981 85
1982 113
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1984 87
1985 121
1986 128
1987 140
1988 121
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1990 122
1991 114
1992 116
1993 128
1994 109
1995 140
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1998 185
1999 151
2000 131
2001 135
2002 122
2003 126
2004 126
2005 123
2006 119
2007 130
2008 106
2009 83
2010 80
2011 111
2012 111
2013 109
2014 110
2015 112
2016 92
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5,541 results

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Page 1
One Dose versus Three Doses of Benzathine Penicillin G in Early Syphilis.
Hook EW 3rd, Dionne JA, Workowski K, McNeil CJ, Taylor SN, Batteiger TA, Dombrowski JC, Mayer KH, Seña AC, Hamill MM, Wiesenfeld HC, Zhu C, Perlowski C, Mejia-Galvis JE, Newman LM. Hook EW 3rd, et al. N Engl J Med. 2025 Sep 4;393(9):869-878. doi: 10.1056/NEJMoa2401802. N Engl J Med. 2025. PMID: 40902161 Free PMC article. Clinical Trial.
BACKGROUND: Controversy persists regarding the appropriate duration of therapy with benzathine penicillin G in persons with early (i.e., primary, secondary, or early latent) syphilis (Treponema pallidum infection). ...CONCLUSIONS: Treatment with one dose of 2.4 mill …
BACKGROUND: Controversy persists regarding the appropriate duration of therapy with benzathine penicillin G in persons with ea …
Cefixime versus benzathine penicillin G for the treatment of early syphilis-a randomized, controlled open label trial.
Klementová T, Zákoucká H, Bížová B, Unemo M, Rob F. Klementová T, et al. J Antimicrob Chemother. 2025 Oct 3;80(10):2654-2658. doi: 10.1093/jac/dkaf268. J Antimicrob Chemother. 2025. PMID: 40795115 Free article. Clinical Trial.
METHODS: A randomized controlled, open label trial in patients with confirmed early syphilis who were randomized to treatment with cefixime 400 mg orally twice a day for 14 consecutive days or to a single dose of benzathine penicillin G (BPG) 2.4 MIU intramuscular. …
METHODS: A randomized controlled, open label trial in patients with confirmed early syphilis who were randomized to treatment with cefixime …
Jarisch-Herxheimer Reaction After Benzathine Penicillin G Treatment in Adults With Early Syphilis: Secondary Analysis of a Randomized Clinical Trial.
Dionne JA, Zhu C, Mejia-Galvis J, Workowski K, Batteiger TA, Dombrowski JC, Mayer KH, McNeil CJ, Seña AC, Taylor S, Wiesenfeld HC, Hamill MM, Perlowski C, Hook EW 3rd. Dionne JA, et al. JAMA Netw Open. 2025 Feb 3;8(2):e2459490. doi: 10.1001/jamanetworkopen.2024.59490. JAMA Netw Open. 2025. PMID: 39946129 Free PMC article. Clinical Trial.
OBJECTIVES: To prospectively assess the incidence of JHR signs and symptoms among adults with early syphilis treated with benzathine penicillin G and to document factors associated with JHR and benzathine penicillin G treatment response outcomes. ...IN …
OBJECTIVES: To prospectively assess the incidence of JHR signs and symptoms among adults with early syphilis treated with benzathine peni …
Benzylpenicillin versus flucloxacillin or cloxacillin for the treatment of penicillin-susceptible Staphylococcus aureus bacteraemia (SNAP): an international, multicentre, open-label, non-inferiority randomised controlled trial.
Staphylococcus aureus Network Adaptive Platform (SNAP) Trial Group. Staphylococcus aureus Network Adaptive Platform (SNAP) Trial Group. Lancet. 2026 Jul 11;408(10550):141-152. doi: 10.1016/S0140-6736(26)00761-0. Epub 2026 Jun 17. Lancet. 2026. PMID: 42309115 Free article. Clinical Trial.
Target attainment of benzylpenicillin in patients with infective endocarditis.
Bock M, Van Hasselt JGC, Fuursted K, Ihlemann N, Gill S, Christiansen U, Bruun NE, Elming H, Povlsen JA, Køber L, Høfsten DE, Fosbøl EL, Pries-Heje MM, Christensen JJ, Rosenvinge FS, Pedersen CT, Helweg-Larsen J, Tønder N, Iversen K, Bundgaard H, Moser C. Bock M, et al. Clin Microbiol Infect. 2025 Aug;31(8):1350-1355. doi: 10.1016/j.cmi.2025.04.025. Epub 2025 Apr 28. Clin Microbiol Infect. 2025. PMID: 40306489 Free article. Clinical Trial.
Management of recurrent tonsillitis in children.
El Hennawi DED, Geneid A, Zaher S, Ahmed MR. El Hennawi DED, et al. Am J Otolaryngol. 2017 Jul-Aug;38(4):371-374. doi: 10.1016/j.amjoto.2017.03.001. Epub 2017 Mar 3. Am J Otolaryngol. 2017. PMID: 28385329 Clinical Trial.
Pharmacokinetics and Safety of Intramuscular Injectable Benzathine Penicillin G in Japanese Healthy Participants.
Li Y, Okayama A, Hagi T, Muto C, Raber S, Nagashima M. Li Y, et al. J Clin Pharmacol. 2024 Oct;64(10):1259-1266. doi: 10.1002/jcph.2454. Epub 2024 May 12. J Clin Pharmacol. 2024. PMID: 38736032 Clinical Trial.
An intramuscular (IM) suspension of benzathine penicillin G (BPG) has been used as first-line therapy for the treatment of syphilis worldwide since its approval in the 1950s. ...After the achievement of C(max), concentrations of penicillin G declined s …
An intramuscular (IM) suspension of benzathine penicillin G (BPG) has been used as first-line therapy for the treatment of syp …
Clinical efficacy of trimethoprim/sulfadiazine and procaine penicillin G in a Streptococcus equi subsp. zooepidemicus infection model in ponies.
Ensink JM, Smit JA, van Duijkeren E. Ensink JM, et al. J Vet Pharmacol Ther. 2003 Aug;26(4):247-52. doi: 10.1046/j.1365-2885.2003.00483.x. J Vet Pharmacol Ther. 2003. PMID: 12887605 Clinical Trial.
Tissue chambers, implanted subcutaneously on both sides of the neck in eight ponies, were inoculated with Streptococcus equi subsp. zooepidemicus in order to compare the clinical efficacy of trimethoprim/sulfadiazine (TMP/SDZ) and penicillin G treatment in a purulen …
Tissue chambers, implanted subcutaneously on both sides of the neck in eight ponies, were inoculated with Streptococcus equi subsp. zooepide …
The streptococcus saga continues.
Denny FW. Denny FW. N Engl J Med. 1991 Jul 11;325(2):127-8. doi: 10.1056/NEJM199107113250211. N Engl J Med. 1991. PMID: 2052048 Clinical Trial. No abstract available.
5,541 results